ObjectiveTo systematically review the intestinal flora diversity profile of pancreatic cancer patients. MethodsThe Cochrane Library, PubMed, Web of Science, EMbase, CNKI, CBM, WanFang Data and VIP databases were electronically searched to collect cross-sectional studies on the intestinal flora diversity profile of pancreatic cancer patients from inception to December 31, 2021. Two reviewers independently screened literature, extracted data and assessed the risk of bias of included studies; then, meta-analysis was performed by using RevMan 5.3 software. ResultsA total of 7 cross-sectional studies involving 250 pancreatic cancer patients and 166 healthy controls were included. The results of meta-analysis showed that: compared with the healthy control group, the intestinal flora of patients with pancreatic cancer α reduced diversity with the Shannon index. High-throughput sequencing found that Proteobacteria and Prevotella were more abundant in pancreatic cancer patients, Firmicutes, Faecalbacterium, Bifidobacterium and Clostridium in pancreatic cancer patients was lower. ConclusionCurrent evidence shows that the intestinal flora of pancreatic cancer patients has certain characteristics. Proteobacteria and Prevotella are relatively abundant in pancreatic cancer patients. Due to limited quality and quantity of the included studies, more high-quality studies are needed to verify above conclusion.
目的 探討64排螺旋CT血管探針技術在評價腎動脈狹窄中的價值。 方法 回顧分析2010年4月－2012年1月51例行64排螺旋CT腎動脈血管成像且腎動脈狹窄患者的臨床資料，對雙側腎動脈行血管探針重組，分析血管狹窄的原因，以及累及范圍、狹窄程度。 結果 51例患者雙側腎動脈共105支（3支副腎動脈），其中管腔正常腎動脈27支，管腔有狹窄腎動脈78支。管腔狹窄者中，腎動脈斑塊血管共65支，累及范圍主要為局限性，以混合性及輕度狹窄為主；腎動脈夾層4支，累及范圍主要為節段性，假腔內無對比劑，真腔輕中度狹窄為主；腎動脈腫瘤包繞共有9支，累及范圍主要為節段性，腔輕度狹窄為主。 結論 64排螺旋CT血管成像清晰顯示腎動脈，血管探針技術分析血管快速、可靠，能準確評價腎動脈狹窄，對指導臨床治療具有重要的意義。