Tuberculosis poses a significant challenge to global public health, characterized by high incidence rates, high drug resistance rates, high mortality rates, and lengthy treatment cycles. Patients with tuberculosis often experience stigma, which can adversely affect their treatment adherence, psychological state, and quality of life. Despite numerous reported interventions both domestically and internationally, there remains a lack of systematic research on personalized intervention strategies tailored to diverse ethnic groups within China’s multicultural context. This article aims to review the domestic and international status of stigma among tuberculosis patients, assessment tools, influencing factors, and intervention strategies, with the goal of providing references for developing effective management strategies for stigma in multicultural tuberculosis patient populations.