Objective To construct an evaluation indicator system for the county-township-village integrated prevention, control and treatment capabilities of chest pain centers in county-level hospitals, providing a reference for improving China’s chest pain treatment network. Methods We determined the initial items of the indicator system based on evidence-based medicine, invited experts to conduct two rounds of inquiry using the Delphi method, discussed and revised the indicators, and determined the weights of each indicator based on the analytic hierarchy process. ResultsA total of 25 experts participated in the consultation. Their areas of expertise included nursing, clinical medicine, medical technology, health service management. The effective response rates of the two rounds of expert consultation questionnaires were 82.76% and 88.00%, respectively, with expert authority levels of 0.84 and 0.88, respectively. In the first round of expert consultation, Kendall coordination coefficient was 0.103 and χ2 value was 151.211 (P<0.001). The Kendall coordination coefficient for the second round was 0.132, with χ2 value of 199.648 (P<0.001). The final evaluation indicator system for the county-township-village integrated prevention, control and treatment capabilities of chest pain centers in county-level hospitals comprised 4 first-level indicators, 10 second-level indicators, and 54 third-level indicators. Conclusion The evaluation indicator system constructed in this study demonstrates scientific validity and reliability, laying a foundation for further validation and application.