The application of subdermal vascular network skin flap (SVN flap) with axial-pattern of artery for skin and soft tissues defects on the extremities of 39 cases was reported. The tyes of flaps included:SVN direct cutaneous artery skin flap in 23 eases, SVN island skin flap in 13 eases, and vaseularized SVN skin flap in 3 cases, All flaps were survived except in one ease of vaseularized SVN skin flap failed. The patients were followed for 6 months to 1 year after operation, the grafted areas showed good looking, no hypertrophy of scar tissue, and normal texture. This type of flap had the advantages of axial-pattern skin flap and that of the SVN skin flap as well, and could be widely applied in the clinical fields.