摘要：目的：探討血小板動態變化與新生兒重癥肺炎之間的關系。方法：測定40例新生兒重癥肺炎患兒急性期（3天）及恢復期（10天）的血小板計數（platelet count, PLT）計數、平均血小板溶劑（mean platelet volume, MPV）、血小板壓積（platelet hematocrit, PCT）及血小板分布寬度（platelet distribution width, PDW），并進行比較。結果：40例重癥肺炎患兒中，PLT隨病情好轉而上升，PCT、MPV、PDW水平隨病情好轉而下降。急性期PLT、PCT、MPV、PDW的水平與恢復期相比，差異有統計學意義（Plt;0.05）。結論：動態的觀察血小板參數及其變化有助于新生兒重癥肺炎的評估及療效觀察。Abstract : Objective: To assess the relationship between neonatal severe pneumonia and platelet. Methods: We test platelet count, mean platelet volume, platelet hematocrit and platelet distribution width in 40 patients whom diagonosed neonatal svere pneumonia; moreover, we compared the platelet change in acute phase and recovery phase. Results: Mean platelet volume, platelet count increased with recovery of pneumonia (Plt;0.05). Conclusion: Observing platelet change is helpful for the evaluation of neonatal pneumonia.