【Abstract】Objective To evaluate the operation of laparoscopic splenectomy(LS), its safety and clinical effects.Methods Literature of the advances of LS were reviewed and analyzed.Results With the development of technology and surgical technique, the indications for LS were widened, the size of spleen plays an important role in the clinical outcome of LS.Conclusion LS has all the advantages of minimally invasive surgery. The application of handassisted technique is safe and feasible for giant spleen. With the accumulation of surgical experiences and technique development, LS will be extensively used in clinic.
目的 探討腹腔鏡下脾切除術(LS)治療特發性血小板減少性紫癜(ITP)的臨床效果。方法 我院2003年1月至2008年8月期間行LS治療ITP患者20例,將術前與術后1、2、7、14、30、90及180 d的血小板計數進行比較。結果 20例ITP患者均順利完成LS,平均手術時間為156 min,術中出血平均50 ml,平均住院時間為9 d。完全停用藥物14例; 4例患者術后需繼續服用激素治療,但激素用量較前明顯減少; 無效2例。總有效率為90%。術后1、2、7、14、30、90及180 d的血小板數量分別為(251.6±91.4)×109/L、(312.6±90.1)×109/L、(343.2±103.7)×109/L、(300.0±98.2)×109/L、(175.6±42.6)×109/L、(151.8±42.1)×109/L及(207.0±53.4)×109/L,分別與術前〔(38.3±19.4)×109/L〕比較,經t檢驗,差異均有統計學意義(P<0.001)。結論 LS治療ITP是可行和安全的,手術效果滿意。