目的 觀察生物衍生膜在治療皮膚潰瘍及缺損創面的臨床效果。方法 2003年3月～2004年10月采用生物衍生膜修復皮膚潰瘍及缺損創面10例，觀察創面愈合情況，并對患者進行隨訪。結果 10例中1例單純使用生物衍生膜治療無效，經創面分泌物培養證實為真菌感染，加用抗真菌藥物治療后創面愈合；余9例創面在3 d分泌物減少，1周后創面開始縮小愈合。患者均獲3個月~1年隨訪，7例外傷及感染創面均愈合，無復發；3例截癱褥瘡創面愈合后有反復。結論生物衍生膜具有皮膚屏障保護、抗炎、減少滲出及促進皮膚創面愈合等作用，為臨床修復皮膚潰瘍缺損創面提供了新的人工組織替代治療途徑。
【摘要】 目的 總結復雜脛骨平臺骨折手術治療的臨床經驗。 方法 2007年1月-2009年12月，采用切開復位內固定治療復雜脛骨平臺骨折56例。男37例，女19例；年齡19～76歲，平均45.6歲。骨折按Schatzker分型:Ⅳ型12例，Ⅴ型26例，Ⅵ型18例。合并半月板損傷20例，膝內側副韌帶損傷9例，外側副韌帶損傷8例，交叉韌帶損傷4例。受傷至手術時間7～14 d，平均9 d。 結果 術后53例切口Ⅰ期愈合；2例術后3 d切口出現淺表感染，1例術后7 d外側切口出現皮膚壞死、鋼板外露，均對癥處理后愈合。56例均獲隨訪，隨訪時間14～49個月，平均19個月。骨折均于術后4～8周愈合，平均6周。并發膝關節僵硬1例、創傷性關節炎2例、異位骨化1例，相應處理后治愈。術后12個月按美國特種外科醫院評分標準評價療效，獲優43例，良5例，可4例，差4例，優良率85.7%。 結論 手術治療復雜脛骨平臺骨折需重視軟組織條件，掌握好手術時機、選擇合適內固定、提高手術技巧、術后有效的功能鍛煉是保證療效的關鍵。【Abstract】 Objective To summarize the clinical experiences of surgical treatment for complex tibial plateau fractures. Methods From January 2007 to December 2009, 56 patients with complex tibial plateau fractures underwent open reduction and internal fixation. The patients included 37 males and 19 females with the age of 19-76 years old (average 45.6 years old). The Schatzker type of the fractures were type Ⅳ in 12 patients, type Ⅴ in 26, and type Ⅵ in 18. The injuries included meniscus injury in 20 patients, injury of lateral collateral ligament of knee in 9, injury of lateral collateral ligament in 8, and cruciate ligaments injury in 4. The time duration between the injury and the surgery was 7-14 days (average 9 days). Results After the surgery, the incision healed at I stage in 53 patients. The incision was superficially infected 3 days after surgery in 2 patients, and the Necrosis of skin around the incision and revealed steel plate were found 7 days after surgery in 1 patient; the injuries was healed after corresponding treatment. All of the patients were followed up with the average follow-up period of 14-49 months (average 19 months). The fractures healed 4-8 weeks (average 6 weeks) after the surgery. Knee joint ankylosis was found in one, traumatic arthritis was found in two, and heterotopic ossification was found in one; the injuries was healed after corresponding treatment. Twelve months after the surgery, the therapeutic effect according to HSS criteria indicated that the score was excellent in 43, good in 5, generally in 4 and poor in 4; with a fine rate of 85.7%. Conclusion Appropriate conditions of the soft tissue, good surgical opportunity, a appropriate fixation, improved surgical technique and effective postoperative functional training are the key points of surgical treatment for complex tibial plateau fractures.