目的 了解單純膽囊切除術圍手術期應用預防性抗生素的作用。方法 對我院普外一科1998年1月至1999年12月2年間所施行的642例擇期單純膽囊切除術圍手術期抗生素的使用、細菌培養結果和切口感染情況進行回顧性分析。結果 642例根據其抗生素應用情況分為未用抗生素組(n＝220)、術前30分鐘一次性給藥組(n＝200)和術后3天持續用藥組(n＝222) 3組，3組患者之性別、年齡構成情況、全身狀況及發生術后切口感染情況間的差異均無顯著性意義(Ｐ＞0.05)； 對642例中隨機選擇52例行術中膽囊膽汁培養，結果47例無細菌生長。結論 對單純膽囊切除術患者術前無感染前提下，不用或僅術前30分鐘一次性使用抗生素是安全可行的，這對縮短患者住院日，減少其醫療費用具有積極的意義。
目的 探討膽石性腸梗阻的診斷與治療方案。方法 對我科1990~1999年診治的11例膽石性腸梗阻的臨床表現、治療結果、術前診斷及手術時機與術式選擇進行回顧性分析。結果 11例患者均痊愈出院。其中1例患者發生急性腎功衰竭，2例患者切口感染。3例未做十二指腸瘺口處理的患者有2例在半年后行膽囊切除十二指腸瘺口修補治愈。結論 根據患者全身情況選擇不同的手術方式均可取得滿意的效果。
【Abstract】Objective To search for the drug that promots the hepatocyte regeneration after partial hepatectomy. Methods Quantitative morphometry technique, 3H-TdR in vivo test and arterial ketone body ratio (AKBR) were employed to evaluate the energy metabolism, DNA synthesis, and liver cell nuclear mitosis and hepatocyte regeneration of the residual liver tissue in rats after partial lobectomy when treated with human growth hormone (hGH) and placebo. Results After partial hepatectomy in the experimental group, liver cell nuclear mitosis，nuclear density, new liver cell numbers, AKBR and 3H-TdR in vivo test were much higher than those in the control group (P＜0.01 or P＜0.05). Conclusion hGH promotes the hepatocyte regeneration of the residual liver.
Objective To enhance survival rate and treatment effect for advanced gallbladder cancer (GBC). MethodsEighty cases of advanced GBC were treated surgically from January 1990 to June 2001.Seventyone cases had obstructive jaundice, 15 had palpable abdominal mass. Extended radical cholecystectomy was performed in 39 cases of advanced GBC in which the tumor invaded the surrounding organs or tissues but without distant metastasis. ResultsFollowup showed that the survival period was between 8 and 37 months (average 18.1 months), 1， 2 and 3year survival rates were 43.6%， 20.5% and 5.1% respectively. Palliative operations were performed in other 41 advanced GBC cases with distant metastasis. All of the patients died within one year. Conclusion This result suggests that extended radical cholecystectomy is effective for advanced GBC.