【摘要】 目的 探討各種不同體外受精（IVF）助孕方案對子宮腺肌病伴不孕癥患者的療效。 方法 對2006年1月-2009年6月進行IVF助孕治療的子宮腺肌病伴不孕癥患者63例的臨床資料進行回顧性分析。根據是否應用長效促性腺激素釋放激素激動劑（GnRH-a）及啟動促性腺激素（Gn）時間分為超長方案、長效GnRH-a后長或短方案、常規長方案3組，對IVF助孕療效進行分析。 結果 3種治療方案的Gn刺激天數、Gn總量、獲卵數、不良反應發生率和流產率比較無統計學意義（Pgt;0.05）；3種治療方案的周期取消率為20.0%、7.7%、30.0%，比較有統計學意義（χ2=5.74，Plt;0.05），方案2的周期取消率低于方案1和方案3，有統計學意義（χ2=7.21，Plt;0.05）；3種治療方案的繼續妊娠率為23.0%、37.0%、15.3%，有統計學意義（χ2=11.31，Plt;0.05），方案2的繼續妊娠率高于方案1和方案3，有統計學意義（χ2=8.52，Plt;0.05）。 結論 與超長方案和常規長方案相比，子宮腺肌病伴不孕癥患者采用長效GnRH-a治療后長方案或短方案行IVF助孕治療，妊娠率升高，周期取消率降低。【Abstract】 Objective To investigate the effect of different in vitro fertilization (IVF) treatment protocols on infertile women with adenomyosis. Methods Sixty-four infertile women with adenomyosis who had IVF treatment cycles from January 2006 to June 2009 were retrospectively analyzed. According to administration of long course gonadotropin-releasing hormone agonist (GnRH-a) and the start time of gonadotropin (Gn), all participants were divided into three groups: the first group with ultra-long term protocol, the second group with long or short term protocol after administration of long course GnRH-a and the third group with routine long term protocol. Results There were no differences among the three groups with regard to days of Gn administration, amounts of Gn administration, numbers of retrieved oocytes, prevalence of poor response and miscarriage (Pgt;0.05). The cancelation rates of the three groups were 20.0%、7.7% and 30.0% respectively. There were significant differences in cancelation rates among the groups (χ2=5.74, Plt;0.05), and the cancelation rate in the second group was significantly lower than the other groups (χ2=7.21, Plt;0.05). The ongoing pregnancy rates of the groups were 23.0%、37.0% and 15.3% respectively. There were significant differences in ongoing pregnancy rates among three groups (χ2=11.31, Plt;0.05), and the ongoing pregnancy rate in the second group was significantly higher than the other groups (χ2=8.52, Plt;0.05). Conclusion Compared with the ultra-long term and routine long term protocol of IVF treatment in infertile woman with adenomyosis, the ongoing pregnancy rate might be higher and the cancelation rate might be lower in the long or short term protocol after administration of long course GnRH-a.