肝血管平滑肌脂肪瘤的影像學表現及其診斷（附3例報道）_《中國普外基礎與臨床雜志》

作者：

路濤 ¹ , 周翔平 ² , 姜興蓮 ³ , 劉翔 ³

1.四川省醫學科學院·四川省人民醫院放射科(成都 610072);;
2.四川大學華西醫院放射科(成都 610041);;
3.四川省醫學科學院·四川省人民醫院病理科(成都 610072);

關鍵詞：

肝臟血管平滑肌脂肪瘤斷層攝影術 X線計算機 HMB-45

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目的探討肝血管平滑肌脂肪瘤（HAML）的CT表現及相關臨床特點。
方法回顧性分析3例經手術病理確診的HAML患者的臨床、CT及病理資料，分析其影像學表現及特點。
結果 3例患者均為女性，其中2例有腹痛表現，1例無任何癥狀。2例實驗室檢查均正常，1例除乙肝標志物（+）外，其余正常。CT表現: 腫瘤位于肝右葉前上段1例，右葉后下段1例，左內葉1例; 腫塊內可見脂肪成分及軟組織成分，其中脂肪成分CT值為-80～-20 HU（平均-50 HU）; 增強后均有不同程度強化，可見強化血管影。術中見均為外生性包塊。免疫組化染色HMB45（+）、αSMA（+）、S100（+），符合血管平滑肌脂肪瘤的診斷。
結論 HAML是一種少見的良性腫瘤，其影像學表現有一定特征性，確診有賴于免疫組化檢測HMB-45。

引用本文： 路濤,周翔平,姜興蓮,劉翔. 肝血管平滑肌脂肪瘤的影像學表現及其診斷（附3例報道）. 中國普外基礎與臨床雜志, 2010, 17(8): 860-864. doi: 復制

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2.	Nguyen TT, Gorman B, Shields D, et al. Malignant hepatic angiomyolipoma: report of a case and review of literature [J]. Am J Surg Pathol, 2008; 32(5): 793798.
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7.	Wang SN, Tsai KB, Lee KT. Hepatic angiomyolipoma with trace amounts of fat: a case report and literature review [J]. J Clin Pathol, 2006; 59(11): 11961199.
8.	Tsui WM, Colombari R, Portmann BC, et al. Hepatic angiomyolipoma: a clinicopathologic study of 30 cases and delineation of unusual morphologic variants [J]. Am J Surg Pathol,1999; 23(1): 3438.
9.	Petrolla AA, Xin W. Hepatic angiomyolipoma [J]. Arch Pathol Lad Med, 2003; 132(10): 16791682.
10.	Low SC, Peh WC, Muttarak M, et al. Imaging features of hepatic angiomyolipoma [J]. J Med Imaging Radiat Oncol, 2008; 52(2): 118123.
11.	Li T, Wang L, Yu HH, et al. Hepatic angiomyolipoma: a retrospective study of 25 cases [J]. Surg Today, 2008; 38(6): 529535.
12.	Ji Y, Zhu X, Xu J, et al. Hepatic angiomyolipoma: a clinicopathologic study of 10 cases [J]. Chin Med J (Engl), 2001; 114(3): 280285.
13.	Yang B, Chen WH, Li QY, et al. Hepatic angiomyolipoma: dynamic computed tomography features and clinical correlation [J]. World J Gastroenterol, 2009; 15(27): 34173420.
14.	Ahmadi T, Itai Y, Takahashi M, et al. Angiomyolipoma of the liver: significance of CT and MR dynamic study [J]. Abdom imaging, 1998; 23(5): 520526.
15.	Wang YJ, Wang YC, Chien CC, et al. Diagnosis of hepatic angiomyolipoma using CT: report of three cases and review of the literature [J]. Clin Radiol, 2009; 64(3): 329334.
16.	馬云海, 李健生, 陸桂君. 肝血管平滑肌脂肪瘤的臨床病理分析 [J]. 中國普外基礎與臨床雜志, 2005; 12(2): 179180.
17.	Jiang TA, Zhao QY, Chen MY, et al. Diagnostic analysis of hepatic angiomyolipoma. Hepatobiliary Pancreat Dis Int, 2005; 4(1): 152155.

1. Tang LH, Hui P, GarciaTsao G, et al. Multiple angiomyolipomata of the liver: a case report [J]. Mod Pathol, 2002; 15(2): 167171.
2. Nguyen TT, Gorman B, Shields D, et al. Malignant hepatic angiomyolipoma: report of a case and review of literature [J]. Am J Surg Pathol, 2008; 32(5): 793798.
3. Deng YF, Lin Q, Zhang SH, et al. Malignant angiomyolipoma in the liver: a case report with pathological and molecular analysis [J]. Pathol Res Pract, 2008; 204(12): 911918.
4. Kannangai R, Diehl AM, Sicklick J, et al. Hepatic angiomyolipoma and hepatic stellate cells share a similar gene expression profile [J]. Hum Pathol, 2005; 36(4): 341347.
5. Nonomura A, Minato H, Kurumaya H. Angiomyolipoma predominantly composed of smooth muscle cells: problems in histologic diagnosis [J]. Histopathology, 1998; 33(1): 2027.
6. Sturtz CL, Dabbs DJ. Angiomyolipomas: the nature and expression of the HMB45 antigen [J]. Mod Pathol, 1994; 7(8): 842845.
7. Wang SN, Tsai KB, Lee KT. Hepatic angiomyolipoma with trace amounts of fat: a case report and literature review [J]. J Clin Pathol, 2006; 59(11): 11961199.
8. Tsui WM, Colombari R, Portmann BC, et al. Hepatic angiomyolipoma: a clinicopathologic study of 30 cases and delineation of unusual morphologic variants [J]. Am J Surg Pathol,1999; 23(1): 3438.
9. Petrolla AA, Xin W. Hepatic angiomyolipoma [J]. Arch Pathol Lad Med, 2003; 132(10): 16791682.
10. Low SC, Peh WC, Muttarak M, et al. Imaging features of hepatic angiomyolipoma [J]. J Med Imaging Radiat Oncol, 2008; 52(2): 118123.
11. Li T, Wang L, Yu HH, et al. Hepatic angiomyolipoma: a retrospective study of 25 cases [J]. Surg Today, 2008; 38(6): 529535.
12. Ji Y, Zhu X, Xu J, et al. Hepatic angiomyolipoma: a clinicopathologic study of 10 cases [J]. Chin Med J (Engl), 2001; 114(3): 280285.
13. Yang B, Chen WH, Li QY, et al. Hepatic angiomyolipoma: dynamic computed tomography features and clinical correlation [J]. World J Gastroenterol, 2009; 15(27): 34173420.
14. Ahmadi T, Itai Y, Takahashi M, et al. Angiomyolipoma of the liver: significance of CT and MR dynamic study [J]. Abdom imaging, 1998; 23(5): 520526.
15. Wang YJ, Wang YC, Chien CC, et al. Diagnosis of hepatic angiomyolipoma using CT: report of three cases and review of the literature [J]. Clin Radiol, 2009; 64(3): 329334.
16. 馬云海, 李健生, 陸桂君. 肝血管平滑肌脂肪瘤的臨床病理分析 [J]. 中國普外基礎與臨床雜志, 2005; 12(2): 179180.
17. Jiang TA, Zhao QY, Chen MY, et al. Diagnostic analysis of hepatic angiomyolipoma. Hepatobiliary Pancreat Dis Int, 2005; 4(1): 152155.

《中國普外基礎與臨床雜志》

肝血管平滑肌脂肪瘤的影像學表現及其診斷（附3例報道）

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《中國普外基礎與臨床雜志》

肝血管平滑肌脂肪瘤的影像學表現及其診斷（附3例報道）

摘要 全文 圖表 視頻 參考文獻 施引文獻 補充材料

Format

Content

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