原發性甲狀腺鱗狀細胞癌的診斷與治療（附1例典型病例報道并文獻復習）_《中國普外基礎與臨床雜志》

作者：

王舉 ¹ , 傅仲鷹 ² , 韓樹海 ¹ , 竇忠霞 ¹ , 王天夫 ¹ , 張劍濤 ¹

1.吉林大學第一醫院普外科(長春 130021);;
2.吉林大學第一醫院耳鼻喉頭頸外科（長春 130021）;

關鍵詞：

甲狀腺鱗狀細胞癌診斷外科治療放射治療

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目的探討原發性甲狀腺鱗狀細胞癌的診斷和治療。
方法回顧性分析我院收治的1例原發性甲狀腺鱗狀細胞癌典型病例，并結合相關文獻復習，探討其診斷和治療。
結果該例腫瘤侵及甲狀軟骨、環狀軟骨和喉，行甲狀腺癌聯合喉擴大切除術。術后發生甲狀旁腺功能低下和手足抽搐，術后第15天出院。隨訪1年健康生存，未見復發和遠處轉移。
結論原發性甲狀腺鱗狀細胞癌罕見，早期診斷困難，惡性程度高，積極手術是首選的治療方法。放射治療可延緩腫瘤的生長、轉移。

引用本文： 王舉,傅仲鷹,韓樹海,竇忠霞,王天夫,張劍濤. 原發性甲狀腺鱗狀細胞癌的診斷與治療（附1例典型病例報道并文獻復習）. 中國普外基礎與臨床雜志, 2010, 17(8): 780-782. doi: 復制

1.	馬靜, 阮標, 李曉江, 等. 原發性甲狀腺鱗狀細胞癌的診治（附1例報告及文獻復習） [J]. 中國耳鼻咽喉顱底外科雜志, 2006; 12(2): 116118.
2.	歐陽, 李玉民, 李汛. 原發性甲狀腺鱗狀細胞癌1例報道 [J]. 中國普外基礎與臨床雜志, 2008; 15(2): 105.
3.	Eom TI, Koo BY, Kim BS, et al. Coexistence of primary squamous cell carcinoma of thyroid with classic papillary thyroid carcinoma [J]. Pathol Int， 2008; 58(12): 797800.
4.	Sahoo M, Bal CS, Bhatnagar D. Primary squamouscell carcinoma of the thyroid gland: new evidence in support of follicular epithelial cell origin [J]. Diagn Cytopathol, 2002; 27(4): 227231.
5.	Saunders CA, Nayar R. Anaplastic spindlecell squamous carcinoma arising in association with tallcell papillary cancer of the thyroid: A potential pitfall [J]. Diagn Cytopathol, 1999; 21(6): 413418.
6.	Rausch T, Benhattar J, Sutter M, et al. Thyroid carcinoma with papillary and squamous features: report of a case with histogenetic considerations [J]. Pathol Res Pract, 2010; 206(4): 263269.
7.	Wiseman SM, Loree TR, Hicks WL Jr, et al. Anaplastic thyroid cancer evolved from papillary carcinoma: demonstration of anaplastic transformation by means of the intersimple sequence repeat polymerase chain reaction [J]. Arch Otolaryngol Head Neck Surg, 2003; 129(1): 96100.
8.	李俊, 唐穎, 邱和生. 橋本病合并原發性甲狀腺鱗癌2例 [J]. 華西醫學, 2002; 17(4): 565.
9.	徐新運, 章宜芬, 吳鴻雁, 等. 甲狀腺原發性乳頭狀癌合并鱗狀細胞癌臨床病理分析 [J]. 東南大學學報(醫學版), 2007; 26(3): 213216.
10.	SanchezSosa S, RiosLuna NP, Tamayo Bdel R, et al. Primary squamous cell carcinoma of the thyroid arising in Hashimoto’s thyroiditis in an adolescent [J]. Pediatr Dev Pathol, 2006; 9(6): 496500.
11.	Sniezek JC, Holtel M. Rare tumors of the thyroid gland [J]. Otolaryngol Clin North Am, 2003; 36(1): 107115.
12.	Simpson WJ, Carruthers J. Squamous cell carcinoma of the thyroid gland [J]. Am J Surg, 1988; 156(1): 4446.
13.	Cook AM, Vini L, Hamer C. Squamous cell carcinoma of the thyroid: outcome of treatment in 16 patients [J]. Eur J Surg Oncol, 1999; 25(6): 606609.
14.	Kumar PV, Malekhusseini SA, Talei AR. Primary squamous cell carcinoma of thyroid diagnosed by fine needle aspiration cytology. A report of two cases [J]. Acta Cytol, 1999; 43(4): 659662.
15.	Long JL, Strocker AM, Wang MB, et al. EGFR expression in primary squamous cell carcinoma of the thyroid [J]. Laryngoscope, 2009; 119(1): 8990.

1. 馬靜, 阮標, 李曉江, 等. 原發性甲狀腺鱗狀細胞癌的診治（附1例報告及文獻復習） [J]. 中國耳鼻咽喉顱底外科雜志, 2006; 12(2): 116118.
2. 歐陽, 李玉民, 李汛. 原發性甲狀腺鱗狀細胞癌1例報道 [J]. 中國普外基礎與臨床雜志, 2008; 15(2): 105.
3. Eom TI, Koo BY, Kim BS, et al. Coexistence of primary squamous cell carcinoma of thyroid with classic papillary thyroid carcinoma [J]. Pathol Int， 2008; 58(12): 797800.
4. Sahoo M, Bal CS, Bhatnagar D. Primary squamouscell carcinoma of the thyroid gland: new evidence in support of follicular epithelial cell origin [J]. Diagn Cytopathol, 2002; 27(4): 227231.
5. Saunders CA, Nayar R. Anaplastic spindlecell squamous carcinoma arising in association with tallcell papillary cancer of the thyroid: A potential pitfall [J]. Diagn Cytopathol, 1999; 21(6): 413418.
6. Rausch T, Benhattar J, Sutter M, et al. Thyroid carcinoma with papillary and squamous features: report of a case with histogenetic considerations [J]. Pathol Res Pract, 2010; 206(4): 263269.
7. Wiseman SM, Loree TR, Hicks WL Jr, et al. Anaplastic thyroid cancer evolved from papillary carcinoma: demonstration of anaplastic transformation by means of the intersimple sequence repeat polymerase chain reaction [J]. Arch Otolaryngol Head Neck Surg, 2003; 129(1): 96100.
8. 李俊, 唐穎, 邱和生. 橋本病合并原發性甲狀腺鱗癌2例 [J]. 華西醫學, 2002; 17(4): 565.
9. 徐新運, 章宜芬, 吳鴻雁, 等. 甲狀腺原發性乳頭狀癌合并鱗狀細胞癌臨床病理分析 [J]. 東南大學學報(醫學版), 2007; 26(3): 213216.
10. SanchezSosa S, RiosLuna NP, Tamayo Bdel R, et al. Primary squamous cell carcinoma of the thyroid arising in Hashimoto’s thyroiditis in an adolescent [J]. Pediatr Dev Pathol, 2006; 9(6): 496500.
11. Sniezek JC, Holtel M. Rare tumors of the thyroid gland [J]. Otolaryngol Clin North Am, 2003; 36(1): 107115.
12. Simpson WJ, Carruthers J. Squamous cell carcinoma of the thyroid gland [J]. Am J Surg, 1988; 156(1): 4446.
13. Cook AM, Vini L, Hamer C. Squamous cell carcinoma of the thyroid: outcome of treatment in 16 patients [J]. Eur J Surg Oncol, 1999; 25(6): 606609.
14. Kumar PV, Malekhusseini SA, Talei AR. Primary squamous cell carcinoma of thyroid diagnosed by fine needle aspiration cytology. A report of two cases [J]. Acta Cytol, 1999; 43(4): 659662.
15. Long JL, Strocker AM, Wang MB, et al. EGFR expression in primary squamous cell carcinoma of the thyroid [J]. Laryngoscope, 2009; 119(1): 8990.

《中國普外基礎與臨床雜志》

原發性甲狀腺鱗狀細胞癌的診斷與治療（附1例典型病例報道并文獻復習）

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《中國普外基礎與臨床雜志》

原發性甲狀腺鱗狀細胞癌的診斷與治療（附1例典型病例報道并文獻復習）

摘要 全文 圖表 視頻 參考文獻 施引文獻 補充材料

Format

Content

摘要全文圖表視頻參考文獻施引文獻補充材料