Beger及Frey手術在胰腺良性疾病及低度惡性腫瘤治療中的應用_《中國普外基礎與臨床雜志》

作者：

陳擁華 , 杜冰清 , 向光明 , 鄭振江 , 劉續寶 , 麥剛

四川大學華西醫院肝膽胰腺外科(四川成都 610041);

關鍵詞：

保留十二指腸胰頭切除術胰腺囊性腫瘤慢性胰腺炎

視頻：

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目的總結Beger及Frey手術的手術技巧及研究應用的新進展。方法分析、評價近年來Beger及Frey手術在胰腺良性疾病及低度惡性腫瘤中的應用技巧，并對其臨床療效研究進展的文獻進行綜述。結果隨著器官保存觀念被廣泛接受，Beger及Frey手術被廣泛應用，與傳統標準術式比較，其具有保留消化道完整、切除胰腺組織少、手術創傷小、術后生存質量高及手術安全性好的優點，但是長期療效優勢隨著時間延長而減弱。結論Beger及Frey手術是相對安全、療效確切的術式，可作為治療胰腺良性疾病及低度惡性腫瘤特別是慢性胰腺炎的標準術式，但尚需進一步探索研究，降低術后并發癥發生率及提高遠期療效。

引用本文： 陳擁華,杜冰清,向光明,鄭振江,劉續寶,麥剛. Beger及Frey手術在胰腺良性疾病及低度惡性腫瘤治療中的應用. 中國普外基礎與臨床雜志, 2011, 18(3): 341-347. doi: 復制

1.	Beger HG, Witte C, Krautzberger W, et al. Experiences with duodenumsparing pancreas head resection in chronic pancreatitis [J]. Chirurg, 1980, 51(5): 303307.
2.	Frey CF, Smith GJ. Description and rationale of a new operation for chronic pancreatitis [J]. Pancreas, 1987, 2(6): 701707.
3.	Müller MW, Friess H, Leitzbach S, et al. Perioperative and followup results after central pancreatic head resection (Berne technique) in a consecutive series of patients with chronic pancreatitis [J]. Am J Surg, 2008, 196(3): 364372.
4.	Strobel O, Büchler MW, Werner J. Surgical therapy of chronic pancreatitis: indications, techniques and results [J]. Int J Surg, 2009, 7(4): 305312.
5.	Varghese TK, Bell RH Jr. Duodenumpreserving head resection for chronic pancreatitis: an institutional experience and national survey of usage [J]. Surgery, 2007, 142(4): 588593.
6.	Lee SE, Jang JY, Hwang DW, et al. Clinical efficacy of organpreserving pancreatectomy for benign or lowgrade malignant potential lesion [J]. J Korean Med Sci, 2010, 25(1): 97103.
7.	Bell RH Jr. Atlas of pancreatic surgery//Bell RH Jr, Rikkers LF, Mulholland MW. Digestive trac surgery. A text and Atlas [M]. Philadelphia, PA: Lippincott Raven, 1996: 10141015.
8.	Horiguchi A, Miyakawa S, Ishihara S, et al. Surgical design and outcome of duodenumpreserving pancreatic head resection for benign or lowgrade malignant tumors [J]. J Hepatobiliary Pancreat Sci, 2010, 17(6): 792797.
9.	劉續寶, 肖乾虎. 腹部外科手術要點及圍手術期處理 [M]. 北京: 科學出版社， 2010: 436437.
10.	Kat’uchová J, Bober J, Závacky P. Chronic pancreatitis, indications for resection procedures and postoperative complications [J]. Rozhl Chir, 2008, 87(4): 200206.
11.	Chirletti P, Peparini N, Caronna R, et al. RouxenY endtoend and endtoside double pancreaticojejunostomy: application of the reconstructive method of the Beger procedure to central pancreatectomy [J]. Langenbecks Arch Surg, 2010, 395(1): 8993.
12.	Hatori T, Imaizumi T, Harada N, et al. Appraisal of the Imaizumi modification of the Beger procedure: the TWMU experience [J]. J Hepatobiliary Pancreat Sci, 2010, 17(6): 752757.
13.	Cataldegirmen G, Bogoevski D, Mann O, et al. Late morbidity after duodenumpreserving pancreatic head resection with bile duct reinsertion into the resection cavity [J]. Br J Surg, 2008, 95(4): 447452.
14.	Beger HG, Schlosser W, Friess HM, et al. Duodenumpreserving head resection in chronic pancreatitis changes the natural course of the disease: a singlecenter 26year experience [J]. Ann Surg, 1999, 230(4): 512519.
15.	Mihaljevic AL, Kleeff J, Friess H. Beger’s operation and the Berne modification: origin and current results [J]. J Hepatobiliary Pancreat Sci, 2010, 17(6): 735744.
16.	Gloor B, Friess H, Uhl W, et al. A modified technique of the Beger and Frey procedure in patients with chronic pancreatitis [J]. Dig Surg, 2001, 18(1): 2125.
17.	Aspelund G, Topazian MD, Lee JH, et al. Improved outcomes for benign disease with limited pancreatic head resection [J]. J Gastrointest Surg, 2005, 9(3): 400409.
18.	Farkas G, Leindler L, Daróczi M, et al. Prospective randomised comparison of organpreserving pancreatic head resection with pyloruspreserving pancreaticoduodenectomy [J]. Langenbecks Arch Surg, 2006, 391(4): 338342.
19.	Riediger H, Adam U, Fischer E, et al. Longterm outcome after resection for chronic pancreatitis in 224 patients [J]. J Gastrointest Surg, 2007, 11(8): 949959.
20.	Diener MK, Bruckner T, Contin P, et al. ChroPactrial: duodenumpreserving pancreatic head resection versus pancreatoduodenectomy for chronic pancreatitis. Trial protocol of a randomised controlled multicentre trial [J]. Trials, 2010, 11: 47.
21.	Busquets J, Fabregat J, Borobia FG, et al. Organpreserving surgery for benign lesions and lowgrade malignancies of the pancreatic head: a matched casecontrol study [J]. Surg Today, 2010, 40(2): 125131.
22.	Frey CF, Mayer KL. Comparison of local resection of the head of the pancreas combined with longitudinal pancreaticojejunostomy (Frey procedure) and duodenumpreserving resection of the pancreatic head (Beger procedure) [J]. World J Surg, 2003, 27(11): 12171230.
23.	鄭振江, 劉續寶, 麥剛, 等. 胰十二指腸切除術和保留十二指腸的胰頭切除術治療慢性胰腺炎的臨床療效比較 [J]. 四川大學學報（醫學版） , 2008, 39(4): 686687.
24.	Egawa S, Motoi F, Sakata N, et al. Assessment of Frey procedures: Japanese experience [J]. J Hepatobiliary Pancreat Sci, 2010, 17(6): 745751.
25.	Schneider CG, Cataldegirmen G, Mann O, et al. Lateral anastomosis techniques: PartingtonRochelle and Vshaped excision [J]. Chirurg, 2009, 80(1): 2833.
26.	Strobel O, Büchler MW, Werner J. Duodenumpreserving pancreatic head resection: technique according to Beger, technique according to Frey and Berne modifications [J]. Chirurg, 2009, 80(1): 2227.
27.	Andersen DK, Frey CF. The evolution of the surgical treatment of chronic pancreatitis [J]. Ann Surg, 2010, 251(1): 1832.
28.	Ebbehj N, Borly L, Bülow J, et al. Pancreatic tissue fluid pressure in chronic pancreatitis. Relation to pain, morphology, and function [J]. Scand J Gastroenterol, 1990, 25(10): 10461051.
29.	Di Sebastiano P, di Mola FF, Bockman DE, et al. Chronic pancreatitis: the perspective of pain generation by neuroimmune interaction [J]. Gut, 2003, 52(6): 907911.
30.	Zhu ZW, Friess H, Wang L, et al. Brainderived neurotrophic factor (BDNF) is upregulated and associated with pain in chronic pancreatitis [J]. Dig Dis Sci, 2001, 46(8): 16331639.
31.	Beger HG, Schlosser W, Poch B, et al. Inflammatory mass in the head of pancreas//Beger HG, Warshaw AL, Büchler MW， et al. The pancreas [M]. Oxford: Blackwell Science, 1998: 757760.
32.	Schlosser W, Siech M, Grich J, et al. Common bile duct stenosis in complicated chronic pancreatitis [J]. Scand J Gastroenterol, 2001, 36(2): 214219.
33.	Heider TR, Azeem S, Galanko JA, et al. The natural history of pancreatitisinduced splenic vein thrombosis [J]. Ann Surg, 2004, 239(6): 876880.
34.	Rieder S, Michalski CW, Friess H. Indications for endoscopic or surgical treatment of chronic pancreatitis [J]. Dig Dis, 2010, 28(2): 344349.
35.	Isaji S. Has the Partington procedure for chronic pancreatitis become a thing of the past? A review of the evidence [J]. J Hepatobiliary Pancreat Sci, 2010, 17(6): 763769.
36.	Menge BA, Schrader H, Breuer TG, et al. Metabolic consequences of a 50% partial pancreatectomy in humans [J]. Diabetologia, 2009, 52(2): 306317.
37.	Diener MK, Rahbari NN, Fischer L, et al. Duodenumpreserving pancreatic head resection versus pancreatoduodenectomy for surgical treatment of chronic pancreatitis: a systematic review and metaanalysis [J]. Ann Surg, 2008, 247(6): 950961.
38.	Mihaljevic AL, Kleeff J, Friess H, et al. Surgical approaches to chronic pancreatitis [J]. Best Pract Res Clin Gastroenterol, 2008, 22(1): 167181.
39.	Bachmann K, Kutup A, Mann O, et al. Surgical treatment in chronic pancreatitis timing and type of procedure [J]. Best Pract Res Clin Gastroenterol, 2010, 24(3): 299310.
40.	Müller MW, Friess H, Martin DJ, et al. Longterm followup of a randomized clinical trial comparing Beger with pyloruspreserving Whipple procedure for chronic pancreatitis [J]. Br J Surg, 2008, 95(3): 350356.
41.	McClaine RJ, Lowy AM, Matthews JB, et al. A comparison of pancreaticoduodenectomy and duodenumpreserving head resection for the treatment of chronic pancreatitis [J]. HPB (Oxford), 2009, 11(8): 677683.
42.	Strate T, Taherpour Z, Bloechle C, et al. Longterm followup of a randomized trial comparing the beger and frey procedures for patients suffering from chronic pancreatitis [J]. Ann Surg, 2005, 241(4): 591598.
43.	Malka D, Hammel P, Sauvanet A, et al. Risk factors for diabetes mellitus in chronic pancreatitis [J]. Gastroenterology, 2000, 119(5): 13241332.
44.	Izbicki JR, Bloechle C, Knoefel WT, et al. Duodenumpreserving resection of the head of the pancreas in chronic pancreatitis. A prospective, randomized trial [J]. Ann Surg, 1995, 221(4): 350358.
45.	Keck T, Wellner UF, Riediger H, et al. Longterm outcome after 92 duodenumpreserving pancreatic head resections for chronic pancreatitis: comparison of Beger and Frey procedures [J]. J Gastrointest Surg, 2010, 14(3): 549556.
46.	Keck T, Marjanovic G, Fernandezdel Castillo C, et al. The inflammatory pancreatic head mass: significant differences in the anatomic pathology of German and American patients with chronic pancreatitis determine very different surgical strategies [J]. Ann Surg, 2009, 249(1): 105110.
47.	Amudhan A, Balachandar TG, Kannan DG, et al. Factors affecting outcome after Frey procedure for chronic pancreatitis [J]. HPB (Oxford), 2008, 10(6): 477482.
48.	劉續寶, 龔軍. 慢性胰腺炎的手術治療方式 [J]. 臨床外科雜志， 2009, 17(6): 378380.
49.	Uguz A, Yakan S, Gurcu B, et al. Xanthogranulomatous pancreatitis treated by duodenumpreserving pancreatic head resection [J]. Hepatobiliary Pancreat Dis Int, 2010, 9(2): 216218.
50.	Beger HG, Rau BM. New advances in pancreatic surgery [J]. Curr Opin Gastroenterol, 2007, 23(5): 522534.
51.	Salvia R, Crippa S, Falconi M, et al. Branchduct intraductal papillary mucinous neoplasms of the pancreas: to operate or not to operate? [J]. Gut, 2007, 56(8): 10861090.
52.	Longnecker DS, Adler G, Hruban RH, et al. Intraductal papillary mucinous neoplasms of the pancreas//Hamilton SR, Aaltonen LA. World Health Organization classification of tumors. Pathology and genetics of tumors of the digestive system [M]. Lyon: IARC Press, 2000: 237241.
53.	Sarr MG, Murr M, Smyrk TC, et al. Primary cystic neoplasms of the pancreas. Neoplastic disorders of emerging importancecurrent stateoftheart and unanswered questions [J]. J Gastrointest Surg, 2003, 7(3): 417428.
54.	Tanaka M, Chari S, Adsay V, et al, International Association of Pancreatology. International consensus guidelines for management of intraductal papillary mucinous neoplasms and mucinous cystic neoplasms of the pancreas [J]. Pancreatology, 2006, 6(12): 1732.
55.	Beger HG, Rau BM, Gansauge F, et al. Duodenumpreserving total pancreatic head resection for cystic neoplasm: a limited but cancerpreventive procedure [J]. Langenbecks Arch Surg, 2008, 393(4): 589598.
56.	Kimura W. IHPBA in Tokyo, 2002: surgical treatment of IPMT vs MCT: a Japanese experience [J]. J Hepatobiliary Pancreat Surg, 2003, 10(2): 156162.
57.	Beger HG, Gansauge F, Siech M, et al. Duodenumpreserving total pancreatic head resection for cystic neoplastic lesions in the head of the pancreas [J]. J Hepatobiliary Pancreat Surg, 2008, 15(2): 149156.
58.	Beger HG, Rau BM, Gansauge F, et al. Duodenumpreserving subtotal and total pancreatic head resections for inflammatory and cystic neoplastic lesions of the pancreas [J]. J Gastrointest Surg, 2008, 12(6): 11271132.
59.	Wang C, Liu T, Wu H, et al. Duodenumpreserving total pancreatic head resection without segment resection of the duodenum for chronic pancreatitis [J]. Langenbecks Arch Surg, 2009, 394(3): 563568.
60.	Pedrazzoli S, Canton SA, Sperti C. Duodenumpreserving versus pyloruspreserving pancreatic head resection for benign and premalignant lesions [J]. J Hepatobiliary Pancreat Sci, 2010 Aug 7 [Epub ahead of print].
61.	Hirano S, Kondo S, Ambo Y, et al. Outcome of duodenumpreserving resection of the head of the pancreas for intraductal papillarymucinous neoplasm [J]. Dig Surg, 2004, 21(3): 242245.
62.	Kanazumi N, Nakao A, Kaneko T, et al. Surgical treatment of intraductal papillarymucinous tumors of the pancreas [J]. Hepatogastroenterology, 2001, 48(40): 967971.
63.	Schütte K, Bornschein J, Kuester D, et al. Fulminant duodenal bleeding as first manifestation of a neuroendocrine carcinoma of the pancreatic head [J]. Med Klin (Munich), 2010, 105(4): 291295.
64.	Schlosser W, Rau BM, Poch B, et al. Surgical treatment of pancreas divisum causing chronic pancreatitis: the outcome benefits of duodenumpreserving pancreatic head resection [J]. J Gastrointest Surg, 2005, 9(5): 710715.
65.	王雪峰, 劉穎斌. 胰腺創傷的診治 [J]. 肝膽外科雜志, 2009, 17(5): 330331.

1. Beger HG, Witte C, Krautzberger W, et al. Experiences with duodenumsparing pancreas head resection in chronic pancreatitis [J]. Chirurg, 1980, 51(5): 303307.
2. Frey CF, Smith GJ. Description and rationale of a new operation for chronic pancreatitis [J]. Pancreas, 1987, 2(6): 701707.
3. Müller MW, Friess H, Leitzbach S, et al. Perioperative and followup results after central pancreatic head resection (Berne technique) in a consecutive series of patients with chronic pancreatitis [J]. Am J Surg, 2008, 196(3): 364372.
4. Strobel O, Büchler MW, Werner J. Surgical therapy of chronic pancreatitis: indications, techniques and results [J]. Int J Surg, 2009, 7(4): 305312.
5. Varghese TK, Bell RH Jr. Duodenumpreserving head resection for chronic pancreatitis: an institutional experience and national survey of usage [J]. Surgery, 2007, 142(4): 588593.
6. Lee SE, Jang JY, Hwang DW, et al. Clinical efficacy of organpreserving pancreatectomy for benign or lowgrade malignant potential lesion [J]. J Korean Med Sci, 2010, 25(1): 97103.
7. Bell RH Jr. Atlas of pancreatic surgery//Bell RH Jr, Rikkers LF, Mulholland MW. Digestive trac surgery. A text and Atlas [M]. Philadelphia, PA: Lippincott Raven, 1996: 10141015.
8. Horiguchi A, Miyakawa S, Ishihara S, et al. Surgical design and outcome of duodenumpreserving pancreatic head resection for benign or lowgrade malignant tumors [J]. J Hepatobiliary Pancreat Sci, 2010, 17(6): 792797.
9. 劉續寶, 肖乾虎. 腹部外科手術要點及圍手術期處理 [M]. 北京: 科學出版社， 2010: 436437.
10. Kat’uchová J, Bober J, Závacky P. Chronic pancreatitis, indications for resection procedures and postoperative complications [J]. Rozhl Chir, 2008, 87(4): 200206.
11. Chirletti P, Peparini N, Caronna R, et al. RouxenY endtoend and endtoside double pancreaticojejunostomy: application of the reconstructive method of the Beger procedure to central pancreatectomy [J]. Langenbecks Arch Surg, 2010, 395(1): 8993.
12. Hatori T, Imaizumi T, Harada N, et al. Appraisal of the Imaizumi modification of the Beger procedure: the TWMU experience [J]. J Hepatobiliary Pancreat Sci, 2010, 17(6): 752757.
13. Cataldegirmen G, Bogoevski D, Mann O, et al. Late morbidity after duodenumpreserving pancreatic head resection with bile duct reinsertion into the resection cavity [J]. Br J Surg, 2008, 95(4): 447452.
14. Beger HG, Schlosser W, Friess HM, et al. Duodenumpreserving head resection in chronic pancreatitis changes the natural course of the disease: a singlecenter 26year experience [J]. Ann Surg, 1999, 230(4): 512519.
15. Mihaljevic AL, Kleeff J, Friess H. Beger’s operation and the Berne modification: origin and current results [J]. J Hepatobiliary Pancreat Sci, 2010, 17(6): 735744.
16. Gloor B, Friess H, Uhl W, et al. A modified technique of the Beger and Frey procedure in patients with chronic pancreatitis [J]. Dig Surg, 2001, 18(1): 2125.
17. Aspelund G, Topazian MD, Lee JH, et al. Improved outcomes for benign disease with limited pancreatic head resection [J]. J Gastrointest Surg, 2005, 9(3): 400409.
18. Farkas G, Leindler L, Daróczi M, et al. Prospective randomised comparison of organpreserving pancreatic head resection with pyloruspreserving pancreaticoduodenectomy [J]. Langenbecks Arch Surg, 2006, 391(4): 338342.
19. Riediger H, Adam U, Fischer E, et al. Longterm outcome after resection for chronic pancreatitis in 224 patients [J]. J Gastrointest Surg, 2007, 11(8): 949959.
20. Diener MK, Bruckner T, Contin P, et al. ChroPactrial: duodenumpreserving pancreatic head resection versus pancreatoduodenectomy for chronic pancreatitis. Trial protocol of a randomised controlled multicentre trial [J]. Trials, 2010, 11: 47.
21. Busquets J, Fabregat J, Borobia FG, et al. Organpreserving surgery for benign lesions and lowgrade malignancies of the pancreatic head: a matched casecontrol study [J]. Surg Today, 2010, 40(2): 125131.
22. Frey CF, Mayer KL. Comparison of local resection of the head of the pancreas combined with longitudinal pancreaticojejunostomy (Frey procedure) and duodenumpreserving resection of the pancreatic head (Beger procedure) [J]. World J Surg, 2003, 27(11): 12171230.
23. 鄭振江, 劉續寶, 麥剛, 等. 胰十二指腸切除術和保留十二指腸的胰頭切除術治療慢性胰腺炎的臨床療效比較 [J]. 四川大學學報（醫學版） , 2008, 39(4): 686687.
24. Egawa S, Motoi F, Sakata N, et al. Assessment of Frey procedures: Japanese experience [J]. J Hepatobiliary Pancreat Sci, 2010, 17(6): 745751.
25. Schneider CG, Cataldegirmen G, Mann O, et al. Lateral anastomosis techniques: PartingtonRochelle and Vshaped excision [J]. Chirurg, 2009, 80(1): 2833.
26. Strobel O, Büchler MW, Werner J. Duodenumpreserving pancreatic head resection: technique according to Beger, technique according to Frey and Berne modifications [J]. Chirurg, 2009, 80(1): 2227.
27. Andersen DK, Frey CF. The evolution of the surgical treatment of chronic pancreatitis [J]. Ann Surg, 2010, 251(1): 1832.
28. Ebbehj N, Borly L, Bülow J, et al. Pancreatic tissue fluid pressure in chronic pancreatitis. Relation to pain, morphology, and function [J]. Scand J Gastroenterol, 1990, 25(10): 10461051.
29. Di Sebastiano P, di Mola FF, Bockman DE, et al. Chronic pancreatitis: the perspective of pain generation by neuroimmune interaction [J]. Gut, 2003, 52(6): 907911.
30. Zhu ZW, Friess H, Wang L, et al. Brainderived neurotrophic factor (BDNF) is upregulated and associated with pain in chronic pancreatitis [J]. Dig Dis Sci, 2001, 46(8): 16331639.
31. Beger HG, Schlosser W, Poch B, et al. Inflammatory mass in the head of pancreas//Beger HG, Warshaw AL, Büchler MW， et al. The pancreas [M]. Oxford: Blackwell Science, 1998: 757760.
32. Schlosser W, Siech M, Grich J, et al. Common bile duct stenosis in complicated chronic pancreatitis [J]. Scand J Gastroenterol, 2001, 36(2): 214219.
33. Heider TR, Azeem S, Galanko JA, et al. The natural history of pancreatitisinduced splenic vein thrombosis [J]. Ann Surg, 2004, 239(6): 876880.
34. Rieder S, Michalski CW, Friess H. Indications for endoscopic or surgical treatment of chronic pancreatitis [J]. Dig Dis, 2010, 28(2): 344349.
35. Isaji S. Has the Partington procedure for chronic pancreatitis become a thing of the past? A review of the evidence [J]. J Hepatobiliary Pancreat Sci, 2010, 17(6): 763769.
36. Menge BA, Schrader H, Breuer TG, et al. Metabolic consequences of a 50% partial pancreatectomy in humans [J]. Diabetologia, 2009, 52(2): 306317.
37. Diener MK, Rahbari NN, Fischer L, et al. Duodenumpreserving pancreatic head resection versus pancreatoduodenectomy for surgical treatment of chronic pancreatitis: a systematic review and metaanalysis [J]. Ann Surg, 2008, 247(6): 950961.
38. Mihaljevic AL, Kleeff J, Friess H, et al. Surgical approaches to chronic pancreatitis [J]. Best Pract Res Clin Gastroenterol, 2008, 22(1): 167181.
39. Bachmann K, Kutup A, Mann O, et al. Surgical treatment in chronic pancreatitis timing and type of procedure [J]. Best Pract Res Clin Gastroenterol, 2010, 24(3): 299310.
40. Müller MW, Friess H, Martin DJ, et al. Longterm followup of a randomized clinical trial comparing Beger with pyloruspreserving Whipple procedure for chronic pancreatitis [J]. Br J Surg, 2008, 95(3): 350356.
41. McClaine RJ, Lowy AM, Matthews JB, et al. A comparison of pancreaticoduodenectomy and duodenumpreserving head resection for the treatment of chronic pancreatitis [J]. HPB (Oxford), 2009, 11(8): 677683.
42. Strate T, Taherpour Z, Bloechle C, et al. Longterm followup of a randomized trial comparing the beger and frey procedures for patients suffering from chronic pancreatitis [J]. Ann Surg, 2005, 241(4): 591598.
43. Malka D, Hammel P, Sauvanet A, et al. Risk factors for diabetes mellitus in chronic pancreatitis [J]. Gastroenterology, 2000, 119(5): 13241332.
44. Izbicki JR, Bloechle C, Knoefel WT, et al. Duodenumpreserving resection of the head of the pancreas in chronic pancreatitis. A prospective, randomized trial [J]. Ann Surg, 1995, 221(4): 350358.
45. Keck T, Wellner UF, Riediger H, et al. Longterm outcome after 92 duodenumpreserving pancreatic head resections for chronic pancreatitis: comparison of Beger and Frey procedures [J]. J Gastrointest Surg, 2010, 14(3): 549556.
46. Keck T, Marjanovic G, Fernandezdel Castillo C, et al. The inflammatory pancreatic head mass: significant differences in the anatomic pathology of German and American patients with chronic pancreatitis determine very different surgical strategies [J]. Ann Surg, 2009, 249(1): 105110.
47. Amudhan A, Balachandar TG, Kannan DG, et al. Factors affecting outcome after Frey procedure for chronic pancreatitis [J]. HPB (Oxford), 2008, 10(6): 477482.
48. 劉續寶, 龔軍. 慢性胰腺炎的手術治療方式 [J]. 臨床外科雜志， 2009, 17(6): 378380.
49. Uguz A, Yakan S, Gurcu B, et al. Xanthogranulomatous pancreatitis treated by duodenumpreserving pancreatic head resection [J]. Hepatobiliary Pancreat Dis Int, 2010, 9(2): 216218.
50. Beger HG, Rau BM. New advances in pancreatic surgery [J]. Curr Opin Gastroenterol, 2007, 23(5): 522534.
51. Salvia R, Crippa S, Falconi M, et al. Branchduct intraductal papillary mucinous neoplasms of the pancreas: to operate or not to operate? [J]. Gut, 2007, 56(8): 10861090.
52. Longnecker DS, Adler G, Hruban RH, et al. Intraductal papillary mucinous neoplasms of the pancreas//Hamilton SR, Aaltonen LA. World Health Organization classification of tumors. Pathology and genetics of tumors of the digestive system [M]. Lyon: IARC Press, 2000: 237241.
53. Sarr MG, Murr M, Smyrk TC, et al. Primary cystic neoplasms of the pancreas. Neoplastic disorders of emerging importancecurrent stateoftheart and unanswered questions [J]. J Gastrointest Surg, 2003, 7(3): 417428.
54. Tanaka M, Chari S, Adsay V, et al, International Association of Pancreatology. International consensus guidelines for management of intraductal papillary mucinous neoplasms and mucinous cystic neoplasms of the pancreas [J]. Pancreatology, 2006, 6(12): 1732.
55. Beger HG, Rau BM, Gansauge F, et al. Duodenumpreserving total pancreatic head resection for cystic neoplasm: a limited but cancerpreventive procedure [J]. Langenbecks Arch Surg, 2008, 393(4): 589598.
56. Kimura W. IHPBA in Tokyo, 2002: surgical treatment of IPMT vs MCT: a Japanese experience [J]. J Hepatobiliary Pancreat Surg, 2003, 10(2): 156162.
57. Beger HG, Gansauge F, Siech M, et al. Duodenumpreserving total pancreatic head resection for cystic neoplastic lesions in the head of the pancreas [J]. J Hepatobiliary Pancreat Surg, 2008, 15(2): 149156.
58. Beger HG, Rau BM, Gansauge F, et al. Duodenumpreserving subtotal and total pancreatic head resections for inflammatory and cystic neoplastic lesions of the pancreas [J]. J Gastrointest Surg, 2008, 12(6): 11271132.
59. Wang C, Liu T, Wu H, et al. Duodenumpreserving total pancreatic head resection without segment resection of the duodenum for chronic pancreatitis [J]. Langenbecks Arch Surg, 2009, 394(3): 563568.
60. Pedrazzoli S, Canton SA, Sperti C. Duodenumpreserving versus pyloruspreserving pancreatic head resection for benign and premalignant lesions [J]. J Hepatobiliary Pancreat Sci, 2010 Aug 7 [Epub ahead of print].
61. Hirano S, Kondo S, Ambo Y, et al. Outcome of duodenumpreserving resection of the head of the pancreas for intraductal papillarymucinous neoplasm [J]. Dig Surg, 2004, 21(3): 242245.
62. Kanazumi N, Nakao A, Kaneko T, et al. Surgical treatment of intraductal papillarymucinous tumors of the pancreas [J]. Hepatogastroenterology, 2001, 48(40): 967971.
63. Schütte K, Bornschein J, Kuester D, et al. Fulminant duodenal bleeding as first manifestation of a neuroendocrine carcinoma of the pancreatic head [J]. Med Klin (Munich), 2010, 105(4): 291295.
64. Schlosser W, Rau BM, Poch B, et al. Surgical treatment of pancreas divisum causing chronic pancreatitis: the outcome benefits of duodenumpreserving pancreatic head resection [J]. J Gastrointest Surg, 2005, 9(5): 710715.
65. 王雪峰, 劉穎斌. 胰腺創傷的診治 [J]. 肝膽外科雜志, 2009, 17(5): 330331.

《中國普外基礎與臨床雜志》

Beger及Frey手術在胰腺良性疾病及低度惡性腫瘤治療中的應用

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《中國普外基礎與臨床雜志》

Beger及Frey手術在胰腺良性疾病及低度惡性腫瘤治療中的應用

摘要 全文 圖表 視頻 參考文獻 施引文獻 補充材料

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摘要全文圖表視頻參考文獻施引文獻補充材料