PET-CT對非小細胞肺癌合并肺不張適形調強放療模擬定位的意義_《華西醫學》

作者：

成都軍區總醫院1.放療科;2.PET中心,四川成都 610083;

關鍵詞：

肺腫瘤肺不張 PET-CT 模擬定位

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目的:探討PET-CT模擬定位對非小細胞肺癌合并肺不張適形調強放療靶區確定的臨床價值。方法:對經影像學和病理證實伴有肺不張的非小細胞肺癌12例患者,進行PET-CT模擬定位。根據PET-CT掃描顯像結果,分別以GTV CT和GTVPET-CT勾畫原發病灶,對用治療計劃系統計算出的兩組數值加以比較。結果:GTVCT平均為141 cm3(99～185 cm3),GTVPET-CT平均為113 cm3(60～165 cm3),兩者差異有顯著性(t=5.497,P lt;0.001)。12例患者原發病灶體積的GTVPET-CT均較GTV CT有不同程度的縮小,平均縮小體積28 cm3(19%)。結論:PET-CT模擬定位,對非小細胞肺癌合并肺不張患者放療靶區的精確定位具有重要的臨床意義。

引用本文： 駱建華,周克,咸婧,潘興國,李小凱. PET-CT對非小細胞肺癌合并肺不張適形調強放療模擬定位的意義. 華西醫學, 2009, 24(4): 942-944. doi: 復制

1.	NESTLE U, WALTER K. 18F-deoxyglucose positron emission tomography (FDG-PET) for the planning of radiotherapy in lung cancer: high impact in patients with atelectasis[J]. Int J Radiat Oncol Biol Phys,1999,44:593-597..
2.	THOMAS L P, BALINGIT A G,MORISON D S, et al. False- positive technetium 99m depreotide scintigraphy resulting from round atelectasis[J]. J Thorac Imaging,2003,18:97-99..
3.	王凱,王綠化,梁軍,等.FDG PET對非小細胞肺癌合并肺不張三維適形放療時靶區確定的臨床意義[J].中華放射腫瘤學雜志,2006,15(1):11-14..
4.	OGAWA MIKAKO. 18F-FDG accumulation in atherosclerotic plaques: immunohistochemical and PET imaging study[J]. J Nucl Med,2004,45:1245-1250..
5.	宋吉清,張成琪.PET-CT對肺癌的臨床應用進展[J].醫學影像學雜志,2005,(15)1:66-68..
6.	PIETERMAN R M, VAN PUTTEN J W. Preoperative staging of non-small-cell lung cancer with positron-emission tomography[J]. N Engl J Med,2000,343:254-261..
7.	KAWABE J, OKAMURA T. Thallium and FDG uptake by atelectasis with bronchogenic carcinoma[J]. Ann Nucl Med,1999,13:273-276..
8.	MCADAMS H P, ERASUMS J J. Evaluation of patients with round atelectasis using 2-[18F]- fluoro-2-deoxy-D-glucose PET[J]. J Comput Assist Tomogr,1998,22:601-604..
9.	BRADLEY J, THORSTAD W L, MUTIC S, et al. Impact of FDG-PET on radiation therapy volume delineation in non-small-cell lung cancer[J]. Int JRadiat Oncol Biol Phys,2004,59:78-86..
10.	ERDI Y E, ROSENZWEIG K, ERDI A K, et al. Radiotherapy treatment planning for patients with non-small cell lung cancer using positron emissiontomography(PET)[J]. Radiother Oncol,2002,62:51-60..
11.	鞏和義,于金明,付政,等.FDG PET對非小細胞肺癌合并肺不張三維適形放療時靶區確定的臨床意義[J].中華腫瘤雜志,2006,28(1):11-14.

1. NESTLE U, WALTER K. 18F-deoxyglucose positron emission tomography (FDG-PET) for the planning of radiotherapy in lung cancer: high impact in patients with atelectasis[J]. Int J Radiat Oncol Biol Phys,1999,44:593-597..
2. THOMAS L P, BALINGIT A G,MORISON D S, et al. False- positive technetium 99m depreotide scintigraphy resulting from round atelectasis[J]. J Thorac Imaging,2003,18:97-99..
3. 王凱,王綠化,梁軍,等.FDG PET對非小細胞肺癌合并肺不張三維適形放療時靶區確定的臨床意義[J].中華放射腫瘤學雜志,2006,15(1):11-14..
4. OGAWA MIKAKO. 18F-FDG accumulation in atherosclerotic plaques: immunohistochemical and PET imaging study[J]. J Nucl Med,2004,45:1245-1250..
5. 宋吉清,張成琪.PET-CT對肺癌的臨床應用進展[J].醫學影像學雜志,2005,(15)1:66-68..
6. PIETERMAN R M, VAN PUTTEN J W. Preoperative staging of non-small-cell lung cancer with positron-emission tomography[J]. N Engl J Med,2000,343:254-261..
7. KAWABE J, OKAMURA T. Thallium and FDG uptake by atelectasis with bronchogenic carcinoma[J]. Ann Nucl Med,1999,13:273-276..
8. MCADAMS H P, ERASUMS J J. Evaluation of patients with round atelectasis using 2-[18F]- fluoro-2-deoxy-D-glucose PET[J]. J Comput Assist Tomogr,1998,22:601-604..
9. BRADLEY J, THORSTAD W L, MUTIC S, et al. Impact of FDG-PET on radiation therapy volume delineation in non-small-cell lung cancer[J]. Int JRadiat Oncol Biol Phys,2004,59:78-86..
10. ERDI Y E, ROSENZWEIG K, ERDI A K, et al. Radiotherapy treatment planning for patients with non-small cell lung cancer using positron emissiontomography(PET)[J]. Radiother Oncol,2002,62:51-60..
11. 鞏和義,于金明,付政,等.FDG PET對非小細胞肺癌合并肺不張三維適形放療時靶區確定的臨床意義[J].中華腫瘤雜志,2006,28(1):11-14.

《華西醫學》

PET-CT對非小細胞肺癌合并肺不張適形調強放療模擬定位的意義

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《華西醫學》

PET-CT對非小細胞肺癌合并肺不張適形調強放療模擬定位的意義

摘要 全文 圖表 視頻 參考文獻 施引文獻 補充材料

Format

Content

摘要全文圖表視頻參考文獻施引文獻補充材料