目的:研究外傷性腦梗死患者血小板P選擇素動態變化的臨床意義。方法:用流式細胞儀測定42例外傷性腦梗死患者,50例無腦梗死外傷患者及40例正常對照者外周血血小板P選擇素。結果:急性期(1周內)外傷性腦梗死患者P選擇素明顯高于無梗死腦外傷患者和健康對照組(P lt;0.01)。14 d時,外傷性腦梗死患者血小板P選擇素表達,與無梗死腦外傷患者和健康對照組無顯著差異(P gt;0.005)。結論:P選擇素參與外傷性腦梗死的病理過程,測定它們有利于外傷性腦梗死的早期診治,改善預后。
引用本文:
曾令春 ,李宗平. 外傷性腦梗死患者P選擇素動態檢測的臨床意義. 華西醫學, 2009, 24(2): 267-268. doi:
復制
1. |
Larsen E,Celi A,Gilbert GE,et al.PADGEM protein:receptor that mediates interaction of activation platelet with neutrophils and monocytes[J].Cell,1989,59:305-312..
|
2. |
Marquordt L,Ruf A,Mansmann U,et al.Course of platete activation markers after ischemic stroke[J].Stroke,2002,33(11):2570-2574..
|
3. |
Haas S,Walenga JM,Jeske UP,et al.Heparininduced thrombocytopenia:the role plateletactivation and therapeutic implication[J].Semin Thromb Hemost,1999,25(Suppl 1):67-75..
|
4. |
李泓,楊期東.花生四烯酸代謝、血小板激活因子、血小板膜蛋白與腦缺血[J].國外醫學神病學神經外科學分冊,1996,23(2):82-83..
|
5. |
Zaremba J,Losy J.sPECAM1 in serum and CSF of acute ischaemic stroke patients[J].Acta Neurol Scand,2002,106(3):292-298..
|
- 1. Larsen E,Celi A,Gilbert GE,et al.PADGEM protein:receptor that mediates interaction of activation platelet with neutrophils and monocytes[J].Cell,1989,59:305-312..
- 2. Marquordt L,Ruf A,Mansmann U,et al.Course of platete activation markers after ischemic stroke[J].Stroke,2002,33(11):2570-2574..
- 3. Haas S,Walenga JM,Jeske UP,et al.Heparininduced thrombocytopenia:the role plateletactivation and therapeutic implication[J].Semin Thromb Hemost,1999,25(Suppl 1):67-75..
- 4. 李泓,楊期東.花生四烯酸代謝、血小板激活因子、血小板膜蛋白與腦缺血[J].國外醫學神病學神經外科學分冊,1996,23(2):82-83..
- 5. Zaremba J,Losy J.sPECAM1 in serum and CSF of acute ischaemic stroke patients[J].Acta Neurol Scand,2002,106(3):292-298..