【摘要】 目的  研究不同壓力二氧化碳（CO2）氣腹對糖代謝的影響。 方法  18只雌性健康新西蘭大白兔按CO2氣腹壓力隨機均分為氣腹壓0 mm Hg （1 mm Hg=0.133 kPa）（Ⅰ組）、氣腹壓10 mm Hg（Ⅱ組）和氣腹壓15 mm Hg（Ⅲ組）。每組兔均在不同的壓力下接受氣腹1 h。在CO2氣腹前（T0）、氣腹后30 min （T1）、氣腹后60 min （T2） 測定動脈血氣分析值、血糖（Glu）、胰島素（Ins）和胰高糖素（Gln）。 結果  氣腹后30 min 、60 min，Ⅱ組與Ⅰ組比較，PaCO2、Glu 、Gln增加（P lt;0.05），pH值和Ins下降（P lt;0.05），Ⅲ組各參數變化更為顯著（P lt;0.01）。結論 CO2氣腹后機體可能處于較強烈的應激狀態，導致血糖升高。
【Abstract】 Objective  To study effects of different intraabdominal pressure of carbon dioxide (CO2) pneumoperitoneum on blood glucose level in rabbits. Methods  Eighteen female healthy rabbits weighed 2.1-3.3 kg were randomly divided into three groups equally based on pneumoperitoneum pressure: 0 mm Hg (1 mm Hg=0.133 kPa) group (groupⅠ),10 mm Hg group (groupⅡ) and 15 mm Hg (groupⅢ). Each group received 1h pneumoperitoneum under diffent pressure. Blood samples were taken before CO2 pneumoperitoneum, at 30 and 60 minutes after pneumoperitoneum for the measure-ments of arterial blood gas, blood glucose (Glu), insulin (Ins) and glucone (Gln). Results  After pneumoperitoneum at 30 and 60 minutes, compared with groupⅠ, PaCO2,Glu and Gln were significantly raised in groupⅡ(P lt;0.05), pH and Ins were markedly decreased (P lt;0.05). Even more significant changes were observed in group Ⅲ(P lt;0.01). Conclusion  After CO2 pneumoperitoneum, body is in a relatively b stress, so blood glucose is decreased.

引用本文： 葉占勇,李軍,劉合年,鞏固,白樹榮,侯景利. 不同壓力二氧化碳氣腹對兔糖代謝的影響. 華西醫學, 2010, 25(9): 1706-1707. doi: 復制