【摘要】 目的  了解青年早期宮頸癌患者在卵巢移位術后的卵巢功能。 方法  2001年1月-2009年12月收治53例年齡26~40歲宮頸癌Ⅰb~Ⅱa期患者，其中27例在宮頸癌根治術中行卵巢移位術為觀察組，26例行宮頸癌根治術切除雙側卵巢的為對照組。術后應用血清卵泡刺激素（FSH）、黃體生成激素（LH）、雌二醇（E2），B超及Kuppermann評分進行卵巢功能測定，隨訪1~4年。 結果  觀察組術后4年內卵巢功能基本正常，對照組術后1個月卵巢功能喪失。觀察組術后4年內血FSH、LH、E2及Kuppermann評分與對照組比較有顯著性意義（P lt;0.05）；兩組復發率比較無顯著性意義（P  gt;0.05）。 結論  青年早期宮頸癌患者在宮頸癌根治術中行卵巢移位術對其卵巢功能無明顯影響。
【Abstract】 Objective  To investigate the function of ovary after ovarian transposition among young patients with early-stage cervical cancer. Methods  A total of 53 young females (26-40 years old) with early stage cervical cancer (FIGO ⅠB or ⅡA) from January 2001 to December 2009. Ovarian transposition was performed at the same time of radical hysterectomy and pelvic lymphadenectomy on 27 patients who were the experimental group. Radical hysterectomy and pelvic lymphadenectomy was done without ovarian transposition on other 26 patients who were the control group. The function of ovarian was evaluated by serum follicle stimulating hormone (FSH), luteinizing hormone (LH), estradiol (E2), the ultrasound examination and Kuppermann score system in all patients during 1- 4 years’ follow-up. Results  The patients in the control group became climacteric in one month after the operation. However, among the patients in the experimental group, their normal ovarian function was preserved within 1- 4 years’ follow-up. There was statistically significant difference between the experimental group and the control group regarding to serum E2, FSH, LH level and Kuppermann score of the patients (P lt;0.05). However, there was no statistically significant difference between the two groups regarding to the recurrence rate (P gt;0.05). Conclusion  Ovarian transposition has statistical significant effect on protection of ovarian function in young patients with early stage cervical cancer, who undergoes radical hysterectomy and pelvic lymphadenectomy.

引用本文： 蘇瑪,潘淑媛. 青年早期宮頸癌患者卵巢移位術后卵巢功能的研究. 華西醫學, 2010, 25(9): 1651-1653. doi: 復制