【摘要】　目的　 Ⅲ型主動脈夾層非體外循環腔內支架隔離術在圍手術期應用硝普鈉控制性降壓易導致精神失常，總結相關護理經驗。　方法　 2009年7月-2010年2月確診Ⅲ型主動脈夾層動脈瘤患者36例，圍手術期應用硝普鈉控制性降壓，均采用非體外循環主動脈腔內隔離術治療，排除手術、麻醉等因素所致腦損傷而產生的術后精神異常。　結果　 有5例出現不同程度精神失常，經加用口服降壓藥，減少硝普鈉泵入劑量，縮短硝普鈉使用時間，經過精心治療及護理，患者精神異常癥狀逐漸減輕直至消失。　結論　 長期、大劑量應用硝普鈉易導致精神失常，需加強護理，及時發現，及時處理。
【Abstract】　Objective　 To summarize the nursing experiences for mental disorders caused by sodium nitroprusside used to cure hypertension in patients receiving off-pump intervention surgery for DeBackey Ⅲ aortic dissection.　Methods　 From July 2009 to February 2010, 36 patients were diagnosed to have DeBackey Ⅲ aortic dissection in our department. All patients received off-pump intervention surgery. We used sodium nitroprusside to control hypertension during the operation. Mental disorders caused by brain damage from surgery, anesthesia and other factors were ruled out.　Results　 Five patients suffered from psychiatric disorders. Oral antihypertensive drugs were used, and we reduced the dose and shortened the time of using sodium nitroprusside. After intensive treatment and care, the symptoms of mental disorders alleviated and disappeared.　Conclusion　 Long-term and large dose of sodium nitroprusside can easily lead to mental disorders, which requires intensive care, timely detection and treatment.

引用本文： 羅天會,曾玲. Ⅲ型主動脈夾層圍手術期應用硝普鈉致精神異常的護理. 華西醫學, 2011, 26(11): 1702-1704. doi: 復制