【摘要】　目的　 分析國內布地奈德、地塞米松吸入治療小兒急性喉炎的療效。　方法　 系統檢索中國生物醫學文獻數字庫（CBM）、中國期刊全文數據庫（CNKI）、維普、萬方數據庫，檢索時間為各個數據庫建庫至2010年7月。納入布地奈德對比地塞米松吸入治療小兒急性喉炎的隨機對照試驗（randomized controlled trial，RCT），對納入研究進行質量評價和Meta分析。　結果　 共納入11個RCT，分析結果提示兩組聲嘶、犬吠樣咳嗽、呼吸困難、喉喘鳴癥狀消失時間差異均存在統計學意義，其MD及95%CI分為:-0.88 （-1.10，-0.65），-1.43 （-2.01，-0.84），-0.48 （-0.63，-0.32），-0.59 （-0.78，-0.41）。　結論　 基于當前國內證據，布地奈德改善小兒急性喉炎梗阻癥狀療效優于地塞米松吸入治療。
【Abstract】　Objective　 To evaluate the effectiveness of budesonide versus dexamethasone for the treatment of acute laryngitis in children of china.　Methods　 Literatures in CBM, CNKI, VIP, WanFang databases were searched from the time of establishment of these databases till July 2010. Randomized controlled trials (RCT) of budesonide versus dexamethasone for the treatment of acute laryngitis in children were gathered, and quality was evaluated and meta-analysis was carried out.　Results　 Eleven RCTs were identified, and meta-analysis indicated that there were significant differences between the two groups in the disappearing time of hoarseness, barking cough, dyspnea and laryngeal stridor. The MD values and their 95% CI were respectively -0.88 (-1.10, -0.65), -1.43 (-2.01, -0.84), -0.48 (-0.63, -0.32), and -0.59 (-0.78, -0.41).　Conclusion　 Based on current evidence in China, budesonide is better than dexamethasone for the improvement of acute laryngitis in children.

引用本文： 張弈. 國內布地奈德比較地塞米松吸入治療小兒急性喉炎的Meta分析. 華西醫學, 2011, 26(7): 1063-1067. doi: 復制