【摘要】 目的 探討減少輸卵管間質部妊娠腹腔鏡術中失血的方法。 方法 選擇2007年1月-2010年6月49例診斷為輸卵管間質部妊娠的患者隨機分成觀察組（24例）和對照組（25例）。觀察組在腹腔鏡切開異位妊娠病灶前于宮角注射垂體后葉素6 U，待子宮收縮后手術；對照組直接切開異位妊娠病灶進行手術。比較兩組手術時間、術中出血量、血壓、術后肛門排氣時間、體溫等方面的差異以及隨訪患者月經恢復時間。 結果 觀察組和對照組手術時間分別為（34.29±7.96）、（53.68±10.48） min，術中出血量為（48.04±9.49）、（85.52±15.24） mL，差異有統計學意義（P lt;0.05）；兩組在術后肛門排氣時間、術后體溫、術前血壓、妊娠病灶切開后5 min的血壓以及觀察組使用垂體后葉素前后的血壓差異均無統計學意義（P gt;0.05）。兩組患者在術后30～41 d月經復潮。 結論 輸卵管間質部妊娠腹腔鏡術中使用垂體后葉素能明顯縮短手術時間和減少術中出血量，不增加持續性宮外孕的發生。
【Abstract】 Objective To explore the method of reducing bleeding in laparoscopy for interstitial pregnancy. Methods Forty-nine patients diagnosed to have interstitial pregnancy between January 2007 and June 2010 were randomly divided into observation group (24 cases) and control group (25 cases). Patients in the observation group were given an injection of 6 U pituitrin in the horn of uterus before the incision of lesions in laparoscopy, and operation was performed after uterine contraction; while the lesions of patients in the control group were directly incised. The differences between the two groups in operation time, blood loss during the operation, blood pressure, exhaust time and temperature were studied and the recovery time of menstrual period was followed up. Results The operation time of the observation group and the control group was (34.29±7.96) minutes and (53.68±10.48) minutes; the blood loss was (48.04±9.49) mL and (85.52±15.24) mL, respectively. The difference in the operation time and blood loss between the two groups was significant (P lt;0.05). The difference in other indexes between the two groups such as the exhaust time, postoperative body temperature, the blood pressure before operation and within five minutes after the incision of the lesion was not statistical (P gt;0.05). The recovery time of menstrual period in the two groups was 30 to 41 days. Conclusion Using pituitrin in laparoscopy for interstitial pregnancy can significantly shorten operation time and reduce blood loss, and will not increase the incidence rate of persistent ectopic pregnancy.
引用本文： 聶小成,常軍,梁家智. 垂體后葉素減少輸卵管間質部妊娠腹腔鏡術中出血的研究. 華西醫學, 2011, 26(4): 562-564. doi: 復制