【摘要】 目的 探索持續非臥床腹膜透析（CAPD）患者年齡與營養狀況的關系，為營養教育提供指導。 方法 對2007年8月-2010年1月腹膜透析177例患者的臨床資料進行回顧性分析，包括血紅蛋白（HGB）、血清白蛋白（ALB）、年齡、體重指數（BMI）、腹膜平衡試驗（PET）、尿素清除指數（Kt/V）、24 h尿蛋白、腹透液漏出蛋白、標準化每日蛋白質分解率（nPCR）等，分析年齡與營養狀況的關系。 結果 老年組（≥60歲）和中青年組（ lt;60歲）ALB分別為（31.54±5.91）、（33.24±4.75）g/L，老年組ALB較低（P lt;0.05）；老年組Kt/V值1.95±0.63和HGB水平（95.25±22.89） g/L均高于青年組（P lt;0.05）。兩組患者營養不良與BMI、PET、每日蛋白漏出總量、nPCR無關。 結論 CAPD老年患者（≥60歲）更容易發生營養不良，且老年組低蛋白血癥與透析充分性無明顯關系。故應加強老年CAPD患者的飲食營養管理指導，設計合理的飲食。
【Abstract】 Objective To investigate the relationship between age and nutrition status of the patients undergoing continuous ambulatory peritoneal dialysis (CAPD), and provide instructions for nutrition education. Methods We retrospectively analyzed the clinical data of 177 patients having undergone CAPD in the Department of Nephrology of West China Hospital between April 2007 and January 2010. Clinical parameters collected included hemoglobin (HGB), serum albumin (ALB), age, body mass index (BMI), results of the peritoneal equilibrium test (PET), urea clearance index (Kt/V), 24-hour urinary protein, protein loss in the peritoneal dialysate, normalized protein catabolic rate (nPCR). Relationship between age and nutrition status in these patients were analyzed. Results Plasma albumin was (31.54±5.91) g/L and (33.24±4.75) g/L respectively in patients of or older than 60 years old (the elderly group) and in patients younger than 60 years old (the younger group). Compared with the younger group, patients in the elderly group had lower ALB (P lt;0.05), but higher Kt/V 1.95±0.63 and hemoglobin level (95.25±22.89) g/L (P lt;0.05). In addition, malnutrition in both groups was not associated with BMI, PET results, daily protein loss in the peritoneal dialysate or nPCR. Conclusions Patients of or older than 60 years old undergoing CAPD are more likely to develop malnutrition, indicating that hypoalbuminemia is not associated with dialysis inadequacy. We advocate enhancing diet nutrition education in elderly CAPD patients and providing them with balanced diet regime.
引用本文： 何青蓮,鐘慧,付平,沙朝暉,唐曉紅,秦敏,刁永書. 持續非臥床腹膜透析患者年齡與營養狀況評價. 華西醫學, 2011, 26(3): 338-340. doi: 復制