Clinical Analysis of Medulla Oblongata Tumor_West China Medical Journal

Authors：

HAO De , YANG Xiang ,  ZHANG Yuekang

Department of Neurosurgery, West China Hospital, Sichuan University, Chengdu, Sichuan 610041, P. R. China;

Corresponding?author：

ZHANG Yuekang, Email: xichuan001@163.com

Keywords：

延髓; 腫瘤; 顯微外科; 伽馬刀

Video：

Export PDF Favorites Scan Get Citation

Abstract Full text Figures/Tables Video References Cited by

目的　探討延髓腫瘤的治療策略，以達到最佳預后。方法　回顧分析2007年1月－2010年12月19例延髓腫瘤患者的臨床資料，其中18例經外科手術治療和病理證實，1例通過影像學確診。結果　12例血管網狀細胞瘤中，11例手術全切，1例手術次全切；2例室管膜瘤均手術全切；2例海綿狀血管瘤分別手術全切及伽馬刀治療；3例膠質瘤均手術部分切除。18例手術治療患者術后神經功能障礙明顯好轉者13例，無明顯變化者3例，2例因術后嚴重并發癥死亡；1例伽馬刀治療患者癥狀好轉。術后隨訪6～48個月，平均24個月。11例恢復工作，4例生活可自理，2例因腫瘤復發死亡。結論　術前通過MRI檢查、術中神經電生理監測及熟練的顯微外科技術是外科治療優勢，伽馬刀治療延髓較小腫瘤有著損傷小的優點，因此制定合理的治療策略有利于提高患者生存質量。

Citation： HAO De,YANG Xiang,ZHANG Yuekang. Clinical Analysis of Medulla Oblongata Tumor. West China Medical Journal, 2012, 27(6): 885-888. doi: Copy

1.	Dan SH, James Z, Donlin M. Surgical resection of intrinsic brain steml lesions: an overview[J]. Neurosurgery, 1990, 27(5): 789-798.
2.	Chang UK, ChoeWJ, Chung SK, et al. Surgical outcome and prognostic factors of spinal intramedullary ependymomas in adults[J]. J Neurooncol, 2002, 57(2): 133-139.
3.	周良輔, 杜固宏, 毛穎, 等. 腦干血管母細胞瘤的診斷和治療[J]. 中華神經外科雜志, 2004, 20(2): 127-131.
4.	Wang C, Zhang J, Liu A, et al. Surgical management of medullary hemangioblastoma. Report of 47 cases [J]. Surg Neurol, 2001, 56(4): 218-227.
5.	Weil RJ, Lonser RR, DeVroom HL, et al. Surgical man-agement of brainstem hemangioblastomas in patients withvon Hippel-Lindau disease [J]. J Neurosurg, 2003, 98(1): 95-105.
6.	Parker F, Aghakhani N, Ducati LG, et al. Results of micro-surgical treatment of medulla oblongata and spinal cordhemangioblastomas: a comparison of two distinct clinicalpatient groups [J]. J Neurooncol, 2009, 93(1): 133-137.
7.	王恩敏, 張南, 王濱江. 伽瑪刀治療血管母細胞瘤臨床分析[J]. 中華外科雜志, 2003, 41(9): 516-520.
8.	Kohno K, Matsul S, Nishizaki A, et al. Successful total removal of intramedullary hemangiohlastoma from the medulla oblongata[J]. Surg Neurol, 1993, 39(2): 25-30.

1. 　Dan SH, James Z, Donlin M. Surgical resection of intrinsic brain steml lesions: an overview[J]. Neurosurgery, 1990, 27(5): 789-798.
2. 　Chang UK, ChoeWJ, Chung SK, et al. Surgical outcome and prognostic factors of spinal intramedullary ependymomas in adults[J]. J Neurooncol, 2002, 57(2): 133-139.
3. 　周良輔, 杜固宏, 毛穎, 等. 腦干血管母細胞瘤的診斷和治療[J]. 中華神經外科雜志, 2004, 20(2): 127-131.
4. 　Wang C, Zhang J, Liu A, et al. Surgical management of medullary hemangioblastoma. Report of 47 cases [J]. Surg Neurol, 2001, 56(4): 218-227.
5. 　Weil RJ, Lonser RR, DeVroom HL, et al. Surgical man-agement of brainstem hemangioblastomas in patients withvon Hippel-Lindau disease [J]. J Neurosurg, 2003, 98(1): 95-105.
6. 　Parker F, Aghakhani N, Ducati LG, et al. Results of micro-surgical treatment of medulla oblongata and spinal cordhemangioblastomas: a comparison of two distinct clinicalpatient groups [J]. J Neurooncol, 2009, 93(1): 133-137.
7. 　王恩敏, 張南, 王濱江. 伽瑪刀治療血管母細胞瘤臨床分析[J]. 中華外科雜志, 2003, 41(9): 516-520.
8. 　Kohno K, Matsul S, Nishizaki A, et al. Successful total removal of intramedullary hemangiohlastoma from the medulla oblongata[J]. Surg Neurol, 1993, 39(2): 25-30.

West China Medical Journal

Clinical Analysis of Medulla Oblongata Tumor

Abstract Full text Figures/Tables Video References Cited by

Format

Content