窄波成像在膀胱癌早期診斷中的應用進展_《華西醫學》

作者：

何宗海 ¹ ,  盧一平 ²

四川大學華西醫院泌尿外科（成都，610041）;

關鍵詞：

膀胱癌窄波成像膀胱鏡研究進展

視頻：

導出 下載 收藏 掃碼 引用

摘要 全文 圖表 視頻 參考文獻 施引文獻 補充材料

膀胱癌是泌尿系統最常見的惡性腫瘤、具有多發、易復發、復發后惡性程度提高等特點。雖然膀胱鏡檢查仍然是早期診斷膀胱癌的主要手段，但是目前常用的普通膀胱鏡不易發現膀胱黏膜的細微病變，可能導致漏診或手術治療不徹底。窄波成像（NBI）是21世紀初新研發的全新診斷技術，其能夠顯著增強膀胱鏡檢查的對比度和清晰度，能夠更加清楚地顯示黏膜表層的毛細血管和腺管開口，不僅可以提高膀胱癌的早期診斷水平，還可以有效地為經尿道膀胱腫瘤電切術手術提供指導。盡管對NBI應用的遠期效果以及能否減少膀胱癌患者術后膀胱灌注和膀胱鏡檢查的次數還有待進一步研究和觀察，但是NBI技術所具有的獨特優勢為膀胱癌的早期診斷和治療提供了新的契機。

引用本文： 何宗海,盧一平. 窄波成像在膀胱癌早期診斷中的應用進展. 華西醫學, 2012, 27(10): 1575-1581. doi: 復制

1.	顧方六. 尿路上皮腫瘤的診斷和治療[M]∥吳階平. 吳階平泌尿外科學. 濟南: 山東科學技術出版社, 2004: 965-966.
2.	虞頌庭, 臧美孚, 夏湣. 尿路上皮腫瘤概論[M]//吳階平. 吳階平泌尿外科學. 濟南: 山東科學技術出版社, 2004: 919-942.
3.	Messing EM. Urothelial tumors of the urinary tract[M]//Wash PC, Retik AB, Vaughan ED Jr, et al. Capbell’s urology. 8th ed. Philadelphia (PA): W.B. Saunders, 2002: 2732-2784.
4.	van der Meijden AP, Sylvester R, Oosterlinck W, et al. EAU guidelines on the diagnosis and treatment of urothelial carcinoma in situ[J]. Eur Urol, 2005, 48(3): 363-371.
5.	Lamm DL. Carcinoma in situ[J]. Urol Clin North Am, 1992, 19(3): 499-508.
6.	俞天麟, 金錫御. 手術學全集: 泌尿外科卷[M]. 北京: 人民軍醫出版社, 1994: 306-307.
7.	Brausi M, Collette L, Kurth K, et al. Variability in the recurrence rate at first follow-up cystoscopy after TUR in stage Ta T1 transitional cell carcinoma of the bladder: a combined analysis of seven EORTC studies[J]. Eur Urol, 2002, 41(5): 523-531.
8.	廖勇, 閻洪濤, 王東, 等. 膀胱移行細胞癌中微血管密度檢測的臨床意義[J]. 現代泌尿外科雜志, 2006, 11(2): 81-82.
9.	Volm M, Koomagi R, Kaufmann M, et al. Microvessel density, expression of proto-oncogenes, resistance-related proteins and incidence of metastases in primary ovarian carcinomas[J]. Clin Exp Metastasis, 1996, 14(3): 209-214.
10.	Hollingeworth HC, Kohn EC, Steinberg SM, et al. Tumor angiogenesis in advanced stage ovarian carcinoma[J]. Am J Pathol, 1996, 147(1): 33-35.
11.	付婭, 郭梅梅, 賀克儉. 窄帶成像內鏡的原理及臨床應用現狀[J]. 醫學綜述, 2009, 15(5): 754-758.
12.	Loidl W, Schmidbauer J, Susani M, et al. Flexible cystoscopy assisted by hexaminolevulinate induced fluorescence: a new approach for bladder Cancer detection and surveillance?[J]. Eur Urol, 2005, 47(3): 323-326.
13.	Tatsugami K, Kuroiwa K, Kamoto T, et al. Evaluation of narrow-band imaging as a complementary method for the detection of bladder cancer[J]. J Endourol, 2010, 24(11): 1807-1811.
14.	Carlo I, Francesco G. NBI improves the detection rate of bladder cancer and leaves the bladder more receptive to the BCG topic treatment[J]. J Endourol, 2011, 25(Suppl 1): A130-A131.
15.	Cauberg EC, Kloen S, Visser M, et al. Narrow band imaging cystoscopy improves the detection of non-muscle-invasive bladder cancer[J]. Urology, 2010, 76(3): 658-663.
16.	陳光富, 王保軍, 馬鑫, 等. NBI技術結合電子軟膀胱鏡在膀胱腫瘤早期診斷中的應用研究[J]. 臨床泌尿外科雜志, 2009, 24(8): 603-605.
17.	宋曉東, 葉章群, 包世新, 等. 窄帶光成像在膀胱癌早期診斷及復發監測中的應用研究[J]. 現代泌尿生殖腫瘤雜志, 2009, 1(6): 325-327.
18.	Bryan RT, Billingham LJ, Wallace DM. Narrow-band imaging flexible cystoscopy in the detection of recurrent urothelial cancer of the bladder[J]. BJU Int, 2008, 101(6): 702-705.
19.	Naselli A, Introini C, Bertolotto F, et al. Narrow band imaging for detecting residual/recurrent cancerous tissue during second transurethral resection of newly diagnosed non-muscle-invasive high-grade bladder Cancer[J]. BJU Int, 2010, 105(2): 208-211.
20.	Herr HW, Donat SM. Reduced bladder tumour recurrence rate associated with narrow-band imaging surveillance cystoscopy[J]. BJU Int, 2011, 107(3): 396-398.
21.	張大宏, 張琦, 劉峰. 窄光成像膀胱鏡在膀胱腫瘤診斷中的應用[J]. 中華泌尿外科雜志, 2010, 31(3): 182-184.
22.	那彥群. 中國泌尿外科疾病診斷治療指南手冊（2011版）[M]. 北京: 人民衛生出版社, 2011: 25-26.
23.	Grossman HB, Gomella L, Fradet Y, et al. A phase III, multicenter comparison of hexaminolevulinate fluorescence cystoscopy and white light cystoscopy for the detection of superficial papillary lesions in patients with bladder Cancer[J]. J Urol, 2007, 178(1): 62-67.
24.	Machida H, Sano Y, Hamamoto Y, et al. Narrow-band imaging in the diagnosis of colorectal mucosal lesions: a pilot study[J]. Endoscopy, 2004, 36(12): 1094-1098.
25.	Ren H, Park KC, Pan R, et al. Early detection of carcinoma in situ of the bladder: a comparative study of white light cystoscopy, narrow band imaging, 5-ALA fluorescence cystoscopy and 3-dimensional optical coherence tomography[J]. J Urol, 2012, 187(3): 1063-1070.
26.	沈益君, 朱一平, 葉定偉, 等. 窄波成像電子膀胱軟鏡在膀胱腫瘤診斷中的應用價值[J]. 中華泌尿外科雜志, 2010, 31(6): 383-385.
27.	Herr H, Donat M, Dalbagni G, et al. Narrow-band imaging cystoscopy to evaluate bladder tumours--individual surgeon variability[J]. BJU Int, 2010, 106(1): 53-55.

1. 　顧方六. 尿路上皮腫瘤的診斷和治療[M]∥吳階平. 吳階平泌尿外科學. 濟南: 山東科學技術出版社, 2004: 965-966.
2. 　虞頌庭, 臧美孚, 夏湣. 尿路上皮腫瘤概論[M]//吳階平. 吳階平泌尿外科學. 濟南: 山東科學技術出版社, 2004: 919-942.
3. 　Messing EM. Urothelial tumors of the urinary tract[M]//Wash PC, Retik AB, Vaughan ED Jr, et al. Capbell’s urology. 8th ed. Philadelphia (PA): W.B. Saunders, 2002: 2732-2784.
4. 　van der Meijden AP, Sylvester R, Oosterlinck W, et al. EAU guidelines on the diagnosis and treatment of urothelial carcinoma in situ[J]. Eur Urol, 2005, 48(3): 363-371.
5. 　Lamm DL. Carcinoma in situ[J]. Urol Clin North Am, 1992, 19(3): 499-508.
6. 　俞天麟, 金錫御. 手術學全集: 泌尿外科卷[M]. 北京: 人民軍醫出版社, 1994: 306-307.
7. 　Brausi M, Collette L, Kurth K, et al. Variability in the recurrence rate at first follow-up cystoscopy after TUR in stage Ta T1 transitional cell carcinoma of the bladder: a combined analysis of seven EORTC studies[J]. Eur Urol, 2002, 41(5): 523-531.
8. 　廖勇, 閻洪濤, 王東, 等. 膀胱移行細胞癌中微血管密度檢測的臨床意義[J]. 現代泌尿外科雜志, 2006, 11(2): 81-82.
9. 　Volm M, Koomagi R, Kaufmann M, et al. Microvessel density, expression of proto-oncogenes, resistance-related proteins and incidence of metastases in primary ovarian carcinomas[J]. Clin Exp Metastasis, 1996, 14(3): 209-214.
10. 　Hollingeworth HC, Kohn EC, Steinberg SM, et al. Tumor angiogenesis in advanced stage ovarian carcinoma[J]. Am J Pathol, 1996, 147(1): 33-35.
11. 　付婭, 郭梅梅, 賀克儉. 窄帶成像內鏡的原理及臨床應用現狀[J]. 醫學綜述, 2009, 15(5): 754-758.
12. 　Loidl W, Schmidbauer J, Susani M, et al. Flexible cystoscopy assisted by hexaminolevulinate induced fluorescence: a new approach for bladder Cancer detection and surveillance?[J]. Eur Urol, 2005, 47(3): 323-326.
13. 　Tatsugami K, Kuroiwa K, Kamoto T, et al. Evaluation of narrow-band imaging as a complementary method for the detection of bladder cancer[J]. J Endourol, 2010, 24(11): 1807-1811.
14. 　Carlo I, Francesco G. NBI improves the detection rate of bladder cancer and leaves the bladder more receptive to the BCG topic treatment[J]. J Endourol, 2011, 25(Suppl 1): A130-A131.
15. 　Cauberg EC, Kloen S, Visser M, et al. Narrow band imaging cystoscopy improves the detection of non-muscle-invasive bladder cancer[J]. Urology, 2010, 76(3): 658-663.
16. 　陳光富, 王保軍, 馬鑫, 等. NBI技術結合電子軟膀胱鏡在膀胱腫瘤早期診斷中的應用研究[J]. 臨床泌尿外科雜志, 2009, 24(8): 603-605.
17. 　宋曉東, 葉章群, 包世新, 等. 窄帶光成像在膀胱癌早期診斷及復發監測中的應用研究[J]. 現代泌尿生殖腫瘤雜志, 2009, 1(6): 325-327.
18. 　Bryan RT, Billingham LJ, Wallace DM. Narrow-band imaging flexible cystoscopy in the detection of recurrent urothelial cancer of the bladder[J]. BJU Int, 2008, 101(6): 702-705.
19. 　Naselli A, Introini C, Bertolotto F, et al. Narrow band imaging for detecting residual/recurrent cancerous tissue during second transurethral resection of newly diagnosed non-muscle-invasive high-grade bladder Cancer[J]. BJU Int, 2010, 105(2): 208-211.
20. 　Herr HW, Donat SM. Reduced bladder tumour recurrence rate associated with narrow-band imaging surveillance cystoscopy[J]. BJU Int, 2011, 107(3): 396-398.
21. 　張大宏, 張琦, 劉峰. 窄光成像膀胱鏡在膀胱腫瘤診斷中的應用[J]. 中華泌尿外科雜志, 2010, 31(3): 182-184.
22. 　那彥群. 中國泌尿外科疾病診斷治療指南手冊（2011版）[M]. 北京: 人民衛生出版社, 2011: 25-26.
23. 　Grossman HB, Gomella L, Fradet Y, et al. A phase III, multicenter comparison of hexaminolevulinate fluorescence cystoscopy and white light cystoscopy for the detection of superficial papillary lesions in patients with bladder Cancer[J]. J Urol, 2007, 178(1): 62-67.
24. 　Machida H, Sano Y, Hamamoto Y, et al. Narrow-band imaging in the diagnosis of colorectal mucosal lesions: a pilot study[J]. Endoscopy, 2004, 36(12): 1094-1098.
25. 　Ren H, Park KC, Pan R, et al. Early detection of carcinoma in situ of the bladder: a comparative study of white light cystoscopy, narrow band imaging, 5-ALA fluorescence cystoscopy and 3-dimensional optical coherence tomography[J]. J Urol, 2012, 187(3): 1063-1070.
26. 　沈益君, 朱一平, 葉定偉, 等. 窄波成像電子膀胱軟鏡在膀胱腫瘤診斷中的應用價值[J]. 中華泌尿外科雜志, 2010, 31(6): 383-385.
27. 　Herr H, Donat M, Dalbagni G, et al. Narrow-band imaging cystoscopy to evaluate bladder tumours--individual surgeon variability[J]. BJU Int, 2010, 106(1): 53-55.

《華西醫學》

窄波成像在膀胱癌早期診斷中的應用進展

摘要 全文 圖表 視頻 參考文獻 施引文獻 補充材料

Format

Content

《華西醫學》

窄波成像在膀胱癌早期診斷中的應用進展

摘要 全文 圖表 視頻 參考文獻 施引文獻 補充材料

Format

Content

摘要全文圖表視頻參考文獻施引文獻補充材料