Clinical Trials of Traditional Chinese Medicine in China: Status and Evaluation_Chinese Journal of Evidence-Based Medicine

Authors：

LI TingQian , WANG Gang , WANG Lei , MAO Bing

Department of Integrated Trad itional Chinese & Western Medicine; West China Hospital; Sichuan University; Che ngdu 610041; China;

Corresponding?author：

Keywords：

Traditional Chinese medicine; Evidence-based medicine; Clinical trial; St atus quo; Evaluation

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The modernization and internationalization of traditional Chinese medicine (TCM) are the key issues we must face up to. The development of TCM needs to depend on the breakthrough of methods and the innovation of ideology, and the international standardization of scientific research evaluation. The clinical evidence from randomized comtrolled trials (RCT) is valuable and reliable. It has shown that the proportion of RCT identified in TCM journals was less than 30%, and the score of RCT’s quality was less than 3 using Jadad scale. However, the number of systematic reviews on TCM is increasing rapidly after the evidence-based medicine (EBM) was introduced and practiced in China. Until 2004, 43 systematic reviews of TCM were published in China, and the quality of RCT included in those reviews was elevated. It has shown that the efficacy and safety of TCM indicated some advances in treatment of certain kind of diseases. It has been realized that RCT are important in TCM, and improving the quality of RCT is the key step for modernization and internationalization of TCM.

Citation： LI TingQian,WANG Gang,WANG Lei,MAO Bing. Clinical Trials of Traditional Chinese Medicine in China: Status and Evaluation. Chinese Journal of Evidence-Based Medicine, 2005, 05(6): 431-437. doi: Copy

1.	王覃, 吳泰相, 劉關鍵. 關于不穩定型心絞痛的中醫藥臨床隨機對照試驗質量的評價[J]. 成都中醫藥大學學報, 2003; 26(2): 52～55.
2.	劉雪梅, 張鳴明, 李幼平, 李廷謙, 何林, 杜亮. 中西醫結合治療嚴重急性呼吸綜合征的隨機對照試驗質量調查[J]. 中國循證醫學雜志, 2003; 3(4) : 298～306.
3.	龍波, 陳玉成, 陳懷生, 曾智. 葛根素治療冠心病心絞痛的臨床研究文獻評價[J]. 中國循證醫學雜志, 2004; 4(5): 333～336.
4.	王蕾, 熊澤宇, 王剛, 李廷謙. 復方丹參滴丸治療穩定型心絞痛隨機對照試驗的系統評價[J]. 中國中西醫結合雜志, 2004; 24(6): 500～504.
5.	吳泰相, 劉關鍵, 張鳴明, 王覃, 倪娟, 魏家富, 周禮鯤, 段鑫, 陳小燕, 鄭潔, 喬杰奇. 青蒿素類藥物預防日本血吸蟲感染效果及安全性的系統評價[J]. 中華醫學雜志, 2003; 83(14): 1219～1224.
6.	吳泰相, 劉保延, 劉關鍵, 趙婷, 彭偉娜, 徐海蓉, 趙娜, 董碧蓉. 中西醫結合治療SARS療效的系統評價[J]. 中國循證醫學雜志. 2004, 4(4): 226～238.
7.	王蕾, 李廷謙, 張瑞明, 毛兵, 常靜, 張穎. 達立通顆粒治療痞滿證(功能性消化不良)的隨機對照雙盲試驗[J]. 中國循證醫學雜志, 2004; 4(4): 239～266.
8.	黃繼漢, 鄭青山, 高蕊, 涂秀華, 徐鳳芹, 孫瑞元. 牛黃降壓片治療原發性高血壓病(肝火亢盛證)的臨床等效性試驗[J]. 中國循證醫學雜志, 2004; 4(4): 249～254.
9.	張穎, 李廷謙, 王剛, 常靜, 毛兵, 王蕾, 遲煥海, 萬美華. 痰熱清注射液治療慢性阻塞性肺疾病急性加重期(痰熱阻肺證)的隨機對照試驗[J]. 中國循證醫學雜志, 2004; 4(5): 300～336.
10.	梁傳余, 溫蓓, 鄭艷, 何剛, 范敏, 黎萬榮, 唐嗣泉, 彭濤, 梁國慶, 王杰, 張玉萍. 鼻淵舒口服液改善慢性鼻竇炎/鼻息肉內窺鏡手術預后的多中心隨機對照試驗[J]. 中國循證醫學雜志, 2004; 4(6): 377～381, 416.
11.	況偉宏, 李進, 李靜, 王雪, 黃明生, 王書臣, 李濤, 黃淑貞, 翁永振, 高成閣, 顏紅. 九味慮平顆粒治療廣泛性焦慮障礙的隨機雙盲雙模擬臨床對照研究[J]. 中國循證醫學雜志, 2004; 4(8): 523～527, 536.
12.	毛兵, 張瑞明, 王蕾, 常靜, 李廷謙. 復方連蒲顆粒治療感冒(風熱證)的隨機對照臨床試驗[J]. 中國循證醫學雜志, 2004; 4(10): 677～684.
13.	王麗春, 雷秉鈞, 劉麗, 劉聰, 張瑞明, 李廷謙. 九味柔肝顆粒治療慢性乙型肝炎肝纖維化的隨機對照雙盲雙模擬對照試驗[J]. 中國循證醫學雜志, 2004; 4(11): 778～782, 793.
14.	陳靜, 劉世喜, 胡國華, 張學淵, 夏彥. 天麻注射液治療眩暈的多中心單盲對照試驗[J]. 中國循證醫學雜志, 2004; 4(12): 864～870.
15.	李廷謙, 毛兵, 常靜, 楊曉楠,王蕾, 張穎, 夏慶, 遲煥海, 巫剛, 熊澤宇, 陳光遠, 黃宗文, 馬建昕, 王剛, 賴珍玉. 中西醫、中醫核心雜志臨床研究文獻評價[J]. 華西醫學, 2000; 15(3): 266～269.
16.	衛茂玲, 辜蕊, 張鳴明, 蘇珊, 劉琴, 鄭柳濤, 劉劍波, 楊曦, 宋黎. 11種地方性中醫藥期刊1995～2000年臨床研究文獻質量的初步分析[J]. 中國循證醫學雜志, 2004; 4(6): 410～413.
17.	郭新峰, 賴世隆, 楊小波, 李先濤, 溫澤淮, 梁偉雄.中醫藥治療中風研究文獻的質量評價[J]. 廣州中醫藥大學學報, 2000; 17(1): 15～19.
18.	李寧, 吳濱, 楊華, 張永玲. 針灸治療老年性癡呆臨床隨機對照試驗方法學評價[J]. 華西醫學, 2000; 15(1): 3～4.
19.	王璽坤, 崔學教, 邱云橋. 中醫藥治療慢性前列腺炎臨床研究文獻質量的調查研究[J]. 中國中醫藥信息雜志, 2001; 8(1): 82～83.
20.	唐雪春, 羅翌, 賴世隆, 郭新峰, 宋蘋. 對雙黃連粉針劑治療急性呼吸道感染研究文獻的質量評價[J]. 廣州中醫藥大學學報, 2002; 19(2): 149～153.
21.	孫潔. 中醫藥治療陽萎文獻質量分析[J]. 湖北中醫學院學報, 2002; 4(3): 10～12.
22.	王澍欣, 洪文. 耳針治療痤瘡臨床研究文獻質量的調查[J]. 中國針灸, 2002; 22(12): 847～849.
23.	段鑫, 周禮鯤, 吳泰相, 劉關鍵. 中醫藥治療冠心病的臨床隨機對照試驗文獻的質量分析[J]. 中國中西醫結合雜志, 2003; 23(3): 164～167.
24.	林曉忠, 吳煥林, 劉澤銀, 文旺秀. 原發性高血壓中醫藥治療性研究文獻評價[J]. 華西醫學, 2003; 18(4): 453～455.
25.	孫大志, 許玲, 姜林娣, 魏品康. 中醫藥治療胃癌臨床研究文獻質量的調查評價[J]. 中國臨床醫學, 2003; 10(6): 833～835.
26.	王喜, 劉慶, 岳小強, 侯鳳剛, 鄧偉哲, 顧偉, 沈旭波. 對中醫藥治療原發性肝癌臨床研究的方法學評價[J]. 湖南中醫學院學報, 2003; 23(4): 50～52.
27.	滕東海, 盧一平, 王莉, 李響, 魏強, 辛宇鵬, 劉孝東, 楊宇如. 中醫藥治療慢性前列腺炎臨床隨機對照試驗的方法學質量評價[J]. 華西醫學, 2004; 19(1): 2～3.
28.	馬斌. 中醫藥治療老年癡呆-隨機對照資料的質量分析和建議[J]. 遼寧中醫雜志, 2004; 31(3): 203～204.
29.	李潔, 史美育, 施毅, 王瓊芳,邸若虹, 倪偉. 中醫藥防治膽石癥文獻的方法學質量評價[J]. 上海中醫藥, 2004; 38(4): 17～18.
30.	周禮鯤, 段鑫, 安寧, 吳泰相, 劉關鍵. 冠心病心絞痛中醫藥研究文獻的質量評價[J]. 中國循證醫學雜志, 2004; 4(4): 258～266.
31.	陳弼滄, 吳秋英, 向成斌, 王麗英. 中醫藥治療糖尿病腎病臨床隨機對照試驗文獻評價[J]. 福建中醫藥, 2004; 35(4): 5～6.
32.	徐珉, 司徒儀, 老鷹榮, 郭新峰, 溫澤淮, 賴世隆. 中醫藥治療子宮內膜異位癥臨床試驗的文獻評價[J]. 廣州中醫藥大學學報, 2004; 21(5): 399～402.
33.	Li TQ, Mao B, Chang J, Yang XL, Wang L, Zhang Y, Xia Q, Chi HH, Wu G, Xiong ZY, Cheng GY, Huang ZW, Ma JX, Wang G, Lai ZY. An evaluation of clinical research literatures in core journals of traditional Chinese medicine integrated with western medicine or traditional Chinese medicine[J]. West China Medical Journal, 2000; 15(3): 266-269.
34.	Tang JL, Zhan SY, Ernst E. Review of randomised controlled trials of traditional Chinese medicine[J]. BMJ, 1999; 319(7203): 160-161.
35.	Wei ML, Gu R, Zhang MM, Su S, Liu Q, Zheng LT, Liu JB, Yang X, Song L. A brief study on the quality of clinical trials in 11 medical journals of traditional Chinese medicine from 1995 to 2000[J]. Chin J of EBM, 2004; 4(6): 410-413.
36.	Guo XF, Lai SL, Yang XB, Li XZ, Wen ZH, Liang WX. Quality analysis of literature of traditional Chinese medicine on clinical study of stroke[J]. Journal of Guangzhou University of Traditional Chinese medicine, 2000; 17(1): 15-19.
37.	Li N, Wu B, Yang H, Zhang YL. Methodological evaluation of randomized controlled trials for AD and VD treated by acupuncture and moxibustion from Chinese medical literatures[J]. West China Medical Journal, 2000; 15(1): 3-4.
38.	Wang XK, Chui XJ, Qiu YQ. Quality analysis of clinical study on the treatment of chronic prostatitis with traditional Chinese medicine[J]. Chinese Journal of information on traditional Chinese medicine, 2001; 8(1) : 82-83.
39.	Tang XC, Luo Y, Lai SL, Guo XF, Song P. Evaluation of studies on Shuang Huanglian injection for acute respiratory infections[J]. Journal of Guangzhou University of traditional Chinese medicine, 2002; 19(2): 149-153.
40.	Sun J. Quality analysis of clinical study on the treatment of Yangwei with traditional Chinese medicine[J]. Journal of Hubei College of Traditional Chinese Medicine, 2002; 4(3): 10-12.
41.	Wang SX, Hong W. Investigation on quality of literature of clinical studies of auricular acupuncture for treatment of acne[J]. Chinese Acupuncture & Moxibustion, 2002; 22(12): 847-849.
42.	Duan X, Zhou LK, Wu TX, Liu GJ. Quality analysis of literatures on clinical randomized controlled trial of coronary heat diseases treated with TCM [J]. Chin J of Integrated Traditional & Western Medicine, 2003; 23(3): 164-167.
43.	Lin XZ, Wu HL, Liu ZY, Wen WX. Evaluation on the articles of randomized controlled trials in primary hypertension treated[J]. West China Medical Journal, 2003; 18(4): 453-455.
44.	Sun DZ, Xu L, Jiang LD, Wei PK. Evaluation of the quality of clinical literatures of traditional Chinese Medicine for gastric carcinoma[J]. Clinical Medical Journal of China, 2003; 10(6): 833-835.
45.	Wang X, Liu Q, Yue XQ, Hou FG, Deng WZ, Gu W, Shen XB. Methodological evaluation of clinical study on traditional Chinese medicine therapies for primary liver carcinoma [J]. Journal of traditional Chinese medicine University of Hunan, 2003; 23(4): 50-52.
46.	Teng DH, Lu YP, Wang L, Li X, Wei Q, Xing YP, Liu XD, Yang YR. Methodological Quality assessment for randomized control trials on traditional Chinese medicine herbs in the treatment of chronic prostatitis[J]. West China Medical Journal, 2004; 19(1): 2-3.
47.	Ma B. Alzheimer’s disease with the treatment of traditional Chinese medicine: quality analysis and advice on randomized controlled trials[J]. Liaoning Journal of traditional Chinese medicine, 2004; 31(3): 203-204.
48.	Methodological quality of the literature involving the treatment of cholelithiasis by Chinese medicine[J]. Shanghai Journal of traditional Chinese medicine, 2004; 38(4): 17-18.
49.	Zhou LK, Duan X, An N, Wu TX, Liu GJ. Quality assessement of the studies of traditional Chinese medicine for coronary heart disease angina[J]. Chin J of EBM, 2004; 4(4): 258-266.
50.	Chen BC, Wu QY, Xiang CB, Wang LY. Quality analysis of randomize clinical trials on the treatment of diabetes mellitus with traditional Chinese medicine[J]. Fujian Journal of Traditional Chinese Medicine, 2004; 35(4): 5-6.
51.	Xu M, Shi TY, Lao YR, Guo XF, Wen ZH, Lai SL. Quality analysis of clinical trials on the treatment of endometriosis with Traditional Chinese Medicine[J]. Journal of Guangzhou University of traditional Chinese medicine, 2004; 21(5): 399-402.
52.	Wang T, Wu TX, Liu GJ. Quality analysis of randomized clinical trials on the treatment of unstable angina pectoris with traditional Chinese medicine[J]. Journal of Chengdu University of Traditional Chinese Medicine, 2003; 26(2): 52-55.
53.	Liu XM, Zhang MM, Li YP, Li TQ, He L, Du L. Quality of randomized controlled trials of traditional Chinese medicine integrated with western medicine for acute respiratory syndrome[J]. Chin J of EBM, 2003; 3(4): 298-306.
54.	Long B, Chen YC, Chen HS, Zheng Z. Quality assessment of clinical studies on puerarin for angina pectoris[J]. Chin J of EBM, 2004; 4(5): 333-336.
55.	Wang L, Xiong ZY, Wang G,Li TQ. Systematic assessment on randomized controlled trials for treatment of stable angina pectoris by compound selvia pellet[J]. Chin J of Integrated Traditional & Western Medicine, 2004; 24(6): 500-504.
56.	Wu TX, Liu GJ, Zhang MM, Wang T, Li J, Wei JF, Zhou LK, Duan X, Chen XY, Zheng J, Qiao JQ. Systematic review of benefits and harms of artemisinin type compounds for preventing schistosomiasis[J]. Natl Med J China, 2003; 83(14): 1219-1224.
57.	Wu TX. Liu BY, Liu GJ, Zhao Ting, Peng WN, Xu HR,Zhao Na, Dong BR. A systematic review of assessing the effect of integrated traditional Chinese medicine with western medicine for severe acute respiratory syndrome[J]. Chin J of EBM, 2004; 4(4): 226-238.
58.	Wang L, Li TQ, Zhang RM, Mao B, Chang J, Zhang Y. Double-blind randomized controlled trial of Dalitong granule in the treatment of Piman syndrome (Functional Dyspepsia) [J]. Chin J of EBM, 2004; 4(4): 239-266.
59.	Huang JH, Zheng QS, Gao R, Tu XH, Xu FQ, Sun RY. Clinical equivalence evaluation on the efficacy and safety of Niuhuangjiangya tablets and pills in the treatment of patients with primary hypertension[J]. Chin J of EBM, 2004; 4(4): 249-254.
60.	Zhang Y, Li TQ, Wang G, Chang J, Mao B, Wang L, Chi HH, Wan MH. Randomized controlled trial of Tanreqing injection in treatment of acute exacerbation of chronic obstructice pulmonary disease (syndrome of retention of Phlegm-heat in the lung) [J]. Chin J of EBM, 2004; 4(5): 300-336.
61.	Liang CY, Wen P, Zheng Y, He G, Fan M, Li WR, Tang SQ, Peng T, Liang GQ, Wang J, Zhang YP. Muti-centre randomized controlled trial of Bi Yuan Shu liquid on patients with chronic nasal sinusitis or nasal polyp after endosoopic sinus surgery[J]. Chin J of EBM, 2004; 4(6): 377-381, 416.
62.	Kuang WH, Li J, Li Jing, Wang X, Huang MS, Wang SC, Li T, Huang SZ, Weng YZ, Gao CG, Yan H. Randomized double-blind controlled trial on effectiveness and safety of Jiu Wei Lv Ping particle in the treatment of generalized anxiety disorder[J]. Chin J of EBM, 2004; 4(8): 523-527, 536.
63.	Mao B, Zhang RM, Wang L, Chang J, Li TQ. Randomized clinical trial of Lianpu granule in the treatment of common cold (Feng-Re Syndrome) [J]. Chin J of EBM, 2004; 4(10): 677-684.
64.	Wang LC, Lei BJ, Liu Li, Liu C, Zhang RM, Li TQ. Jiuweirougan granule in the treatment of chronic hepatitis with hepatic fibrosis: a double-blind randomized controlled trial[J]. Chin J of EBM, 2004; 4(11): 778-782, 793.
65.	Chen J, Liu SX, Hu GH, Zhang XY, Xia Y. Gastrodin injection in the treatment of Vertigo: a multi-center single-blind randomized controlled trial[J]. Chin J of EBM, 2004; 4(12): 864-870.

1. 王覃, 吳泰相, 劉關鍵. 關于不穩定型心絞痛的中醫藥臨床隨機對照試驗質量的評價[J]. 成都中醫藥大學學報, 2003; 26(2): 52～55.
2. 劉雪梅, 張鳴明, 李幼平, 李廷謙, 何林, 杜亮. 中西醫結合治療嚴重急性呼吸綜合征的隨機對照試驗質量調查[J]. 中國循證醫學雜志, 2003; 3(4) : 298～306.
3. 龍波, 陳玉成, 陳懷生, 曾智. 葛根素治療冠心病心絞痛的臨床研究文獻評價[J]. 中國循證醫學雜志, 2004; 4(5): 333～336.
4. 王蕾, 熊澤宇, 王剛, 李廷謙. 復方丹參滴丸治療穩定型心絞痛隨機對照試驗的系統評價[J]. 中國中西醫結合雜志, 2004; 24(6): 500～504.
5. 吳泰相, 劉關鍵, 張鳴明, 王覃, 倪娟, 魏家富, 周禮鯤, 段鑫, 陳小燕, 鄭潔, 喬杰奇. 青蒿素類藥物預防日本血吸蟲感染效果及安全性的系統評價[J]. 中華醫學雜志, 2003; 83(14): 1219～1224.
6. 吳泰相, 劉保延, 劉關鍵, 趙婷, 彭偉娜, 徐海蓉, 趙娜, 董碧蓉. 中西醫結合治療SARS療效的系統評價[J]. 中國循證醫學雜志. 2004, 4(4): 226～238.
7. 王蕾, 李廷謙, 張瑞明, 毛兵, 常靜, 張穎. 達立通顆粒治療痞滿證(功能性消化不良)的隨機對照雙盲試驗[J]. 中國循證醫學雜志, 2004; 4(4): 239～266.
8. 黃繼漢, 鄭青山, 高蕊, 涂秀華, 徐鳳芹, 孫瑞元. 牛黃降壓片治療原發性高血壓病(肝火亢盛證)的臨床等效性試驗[J]. 中國循證醫學雜志, 2004; 4(4): 249～254.
9. 張穎, 李廷謙, 王剛, 常靜, 毛兵, 王蕾, 遲煥海, 萬美華. 痰熱清注射液治療慢性阻塞性肺疾病急性加重期(痰熱阻肺證)的隨機對照試驗[J]. 中國循證醫學雜志, 2004; 4(5): 300～336.
10. 梁傳余, 溫蓓, 鄭艷, 何剛, 范敏, 黎萬榮, 唐嗣泉, 彭濤, 梁國慶, 王杰, 張玉萍. 鼻淵舒口服液改善慢性鼻竇炎/鼻息肉內窺鏡手術預后的多中心隨機對照試驗[J]. 中國循證醫學雜志, 2004; 4(6): 377～381, 416.
11. 況偉宏, 李進, 李靜, 王雪, 黃明生, 王書臣, 李濤, 黃淑貞, 翁永振, 高成閣, 顏紅. 九味慮平顆粒治療廣泛性焦慮障礙的隨機雙盲雙模擬臨床對照研究[J]. 中國循證醫學雜志, 2004; 4(8): 523～527, 536.
12. 毛兵, 張瑞明, 王蕾, 常靜, 李廷謙. 復方連蒲顆粒治療感冒(風熱證)的隨機對照臨床試驗[J]. 中國循證醫學雜志, 2004; 4(10): 677～684.
13. 王麗春, 雷秉鈞, 劉麗, 劉聰, 張瑞明, 李廷謙. 九味柔肝顆粒治療慢性乙型肝炎肝纖維化的隨機對照雙盲雙模擬對照試驗[J]. 中國循證醫學雜志, 2004; 4(11): 778～782, 793.
14. 陳靜, 劉世喜, 胡國華, 張學淵, 夏彥. 天麻注射液治療眩暈的多中心單盲對照試驗[J]. 中國循證醫學雜志, 2004; 4(12): 864～870.
15. 李廷謙, 毛兵, 常靜, 楊曉楠,王蕾, 張穎, 夏慶, 遲煥海, 巫剛, 熊澤宇, 陳光遠, 黃宗文, 馬建昕, 王剛, 賴珍玉. 中西醫、中醫核心雜志臨床研究文獻評價[J]. 華西醫學, 2000; 15(3): 266～269.
16. 衛茂玲, 辜蕊, 張鳴明, 蘇珊, 劉琴, 鄭柳濤, 劉劍波, 楊曦, 宋黎. 11種地方性中醫藥期刊1995～2000年臨床研究文獻質量的初步分析[J]. 中國循證醫學雜志, 2004; 4(6): 410～413.
17. 郭新峰, 賴世隆, 楊小波, 李先濤, 溫澤淮, 梁偉雄.中醫藥治療中風研究文獻的質量評價[J]. 廣州中醫藥大學學報, 2000; 17(1): 15～19.
18. 李寧, 吳濱, 楊華, 張永玲. 針灸治療老年性癡呆臨床隨機對照試驗方法學評價[J]. 華西醫學, 2000; 15(1): 3～4.
19. 王璽坤, 崔學教, 邱云橋. 中醫藥治療慢性前列腺炎臨床研究文獻質量的調查研究[J]. 中國中醫藥信息雜志, 2001; 8(1): 82～83.
20. 唐雪春, 羅翌, 賴世隆, 郭新峰, 宋蘋. 對雙黃連粉針劑治療急性呼吸道感染研究文獻的質量評價[J]. 廣州中醫藥大學學報, 2002; 19(2): 149～153.
21. 孫潔. 中醫藥治療陽萎文獻質量分析[J]. 湖北中醫學院學報, 2002; 4(3): 10～12.
22. 王澍欣, 洪文. 耳針治療痤瘡臨床研究文獻質量的調查[J]. 中國針灸, 2002; 22(12): 847～849.
23. 段鑫, 周禮鯤, 吳泰相, 劉關鍵. 中醫藥治療冠心病的臨床隨機對照試驗文獻的質量分析[J]. 中國中西醫結合雜志, 2003; 23(3): 164～167.
24. 林曉忠, 吳煥林, 劉澤銀, 文旺秀. 原發性高血壓中醫藥治療性研究文獻評價[J]. 華西醫學, 2003; 18(4): 453～455.
25. 孫大志, 許玲, 姜林娣, 魏品康. 中醫藥治療胃癌臨床研究文獻質量的調查評價[J]. 中國臨床醫學, 2003; 10(6): 833～835.
26. 王喜, 劉慶, 岳小強, 侯鳳剛, 鄧偉哲, 顧偉, 沈旭波. 對中醫藥治療原發性肝癌臨床研究的方法學評價[J]. 湖南中醫學院學報, 2003; 23(4): 50～52.
27. 滕東海, 盧一平, 王莉, 李響, 魏強, 辛宇鵬, 劉孝東, 楊宇如. 中醫藥治療慢性前列腺炎臨床隨機對照試驗的方法學質量評價[J]. 華西醫學, 2004; 19(1): 2～3.
28. 馬斌. 中醫藥治療老年癡呆-隨機對照資料的質量分析和建議[J]. 遼寧中醫雜志, 2004; 31(3): 203～204.
29. 李潔, 史美育, 施毅, 王瓊芳,邸若虹, 倪偉. 中醫藥防治膽石癥文獻的方法學質量評價[J]. 上海中醫藥, 2004; 38(4): 17～18.
30. 周禮鯤, 段鑫, 安寧, 吳泰相, 劉關鍵. 冠心病心絞痛中醫藥研究文獻的質量評價[J]. 中國循證醫學雜志, 2004; 4(4): 258～266.
31. 陳弼滄, 吳秋英, 向成斌, 王麗英. 中醫藥治療糖尿病腎病臨床隨機對照試驗文獻評價[J]. 福建中醫藥, 2004; 35(4): 5～6.
32. 徐珉, 司徒儀, 老鷹榮, 郭新峰, 溫澤淮, 賴世隆. 中醫藥治療子宮內膜異位癥臨床試驗的文獻評價[J]. 廣州中醫藥大學學報, 2004; 21(5): 399～402.
33. Li TQ, Mao B, Chang J, Yang XL, Wang L, Zhang Y, Xia Q, Chi HH, Wu G, Xiong ZY, Cheng GY, Huang ZW, Ma JX, Wang G, Lai ZY. An evaluation of clinical research literatures in core journals of traditional Chinese medicine integrated with western medicine or traditional Chinese medicine[J]. West China Medical Journal, 2000; 15(3): 266-269.
34. Tang JL, Zhan SY, Ernst E. Review of randomised controlled trials of traditional Chinese medicine[J]. BMJ, 1999; 319(7203): 160-161.
35. Wei ML, Gu R, Zhang MM, Su S, Liu Q, Zheng LT, Liu JB, Yang X, Song L. A brief study on the quality of clinical trials in 11 medical journals of traditional Chinese medicine from 1995 to 2000[J]. Chin J of EBM, 2004; 4(6): 410-413.
36. Guo XF, Lai SL, Yang XB, Li XZ, Wen ZH, Liang WX. Quality analysis of literature of traditional Chinese medicine on clinical study of stroke[J]. Journal of Guangzhou University of Traditional Chinese medicine, 2000; 17(1): 15-19.
37. Li N, Wu B, Yang H, Zhang YL. Methodological evaluation of randomized controlled trials for AD and VD treated by acupuncture and moxibustion from Chinese medical literatures[J]. West China Medical Journal, 2000; 15(1): 3-4.
38. Wang XK, Chui XJ, Qiu YQ. Quality analysis of clinical study on the treatment of chronic prostatitis with traditional Chinese medicine[J]. Chinese Journal of information on traditional Chinese medicine, 2001; 8(1) : 82-83.
39. Tang XC, Luo Y, Lai SL, Guo XF, Song P. Evaluation of studies on Shuang Huanglian injection for acute respiratory infections[J]. Journal of Guangzhou University of traditional Chinese medicine, 2002; 19(2): 149-153.
40. Sun J. Quality analysis of clinical study on the treatment of Yangwei with traditional Chinese medicine[J]. Journal of Hubei College of Traditional Chinese Medicine, 2002; 4(3): 10-12.
41. Wang SX, Hong W. Investigation on quality of literature of clinical studies of auricular acupuncture for treatment of acne[J]. Chinese Acupuncture & Moxibustion, 2002; 22(12): 847-849.
42. Duan X, Zhou LK, Wu TX, Liu GJ. Quality analysis of literatures on clinical randomized controlled trial of coronary heat diseases treated with TCM [J]. Chin J of Integrated Traditional & Western Medicine, 2003; 23(3): 164-167.
43. Lin XZ, Wu HL, Liu ZY, Wen WX. Evaluation on the articles of randomized controlled trials in primary hypertension treated[J]. West China Medical Journal, 2003; 18(4): 453-455.
44. Sun DZ, Xu L, Jiang LD, Wei PK. Evaluation of the quality of clinical literatures of traditional Chinese Medicine for gastric carcinoma[J]. Clinical Medical Journal of China, 2003; 10(6): 833-835.
45. Wang X, Liu Q, Yue XQ, Hou FG, Deng WZ, Gu W, Shen XB. Methodological evaluation of clinical study on traditional Chinese medicine therapies for primary liver carcinoma [J]. Journal of traditional Chinese medicine University of Hunan, 2003; 23(4): 50-52.
46. Teng DH, Lu YP, Wang L, Li X, Wei Q, Xing YP, Liu XD, Yang YR. Methodological Quality assessment for randomized control trials on traditional Chinese medicine herbs in the treatment of chronic prostatitis[J]. West China Medical Journal, 2004; 19(1): 2-3.
47. Ma B. Alzheimer’s disease with the treatment of traditional Chinese medicine: quality analysis and advice on randomized controlled trials[J]. Liaoning Journal of traditional Chinese medicine, 2004; 31(3): 203-204.
48. Methodological quality of the literature involving the treatment of cholelithiasis by Chinese medicine[J]. Shanghai Journal of traditional Chinese medicine, 2004; 38(4): 17-18.
49. Zhou LK, Duan X, An N, Wu TX, Liu GJ. Quality assessement of the studies of traditional Chinese medicine for coronary heart disease angina[J]. Chin J of EBM, 2004; 4(4): 258-266.
50. Chen BC, Wu QY, Xiang CB, Wang LY. Quality analysis of randomize clinical trials on the treatment of diabetes mellitus with traditional Chinese medicine[J]. Fujian Journal of Traditional Chinese Medicine, 2004; 35(4): 5-6.
51. Xu M, Shi TY, Lao YR, Guo XF, Wen ZH, Lai SL. Quality analysis of clinical trials on the treatment of endometriosis with Traditional Chinese Medicine[J]. Journal of Guangzhou University of traditional Chinese medicine, 2004; 21(5): 399-402.
52. Wang T, Wu TX, Liu GJ. Quality analysis of randomized clinical trials on the treatment of unstable angina pectoris with traditional Chinese medicine[J]. Journal of Chengdu University of Traditional Chinese Medicine, 2003; 26(2): 52-55.
53. Liu XM, Zhang MM, Li YP, Li TQ, He L, Du L. Quality of randomized controlled trials of traditional Chinese medicine integrated with western medicine for acute respiratory syndrome[J]. Chin J of EBM, 2003; 3(4): 298-306.
54. Long B, Chen YC, Chen HS, Zheng Z. Quality assessment of clinical studies on puerarin for angina pectoris[J]. Chin J of EBM, 2004; 4(5): 333-336.
55. Wang L, Xiong ZY, Wang G,Li TQ. Systematic assessment on randomized controlled trials for treatment of stable angina pectoris by compound selvia pellet[J]. Chin J of Integrated Traditional & Western Medicine, 2004; 24(6): 500-504.
56. Wu TX, Liu GJ, Zhang MM, Wang T, Li J, Wei JF, Zhou LK, Duan X, Chen XY, Zheng J, Qiao JQ. Systematic review of benefits and harms of artemisinin type compounds for preventing schistosomiasis[J]. Natl Med J China, 2003; 83(14): 1219-1224.
57. Wu TX. Liu BY, Liu GJ, Zhao Ting, Peng WN, Xu HR,Zhao Na, Dong BR. A systematic review of assessing the effect of integrated traditional Chinese medicine with western medicine for severe acute respiratory syndrome[J]. Chin J of EBM, 2004; 4(4): 226-238.
58. Wang L, Li TQ, Zhang RM, Mao B, Chang J, Zhang Y. Double-blind randomized controlled trial of Dalitong granule in the treatment of Piman syndrome (Functional Dyspepsia) [J]. Chin J of EBM, 2004; 4(4): 239-266.
59. Huang JH, Zheng QS, Gao R, Tu XH, Xu FQ, Sun RY. Clinical equivalence evaluation on the efficacy and safety of Niuhuangjiangya tablets and pills in the treatment of patients with primary hypertension[J]. Chin J of EBM, 2004; 4(4): 249-254.
60. Zhang Y, Li TQ, Wang G, Chang J, Mao B, Wang L, Chi HH, Wan MH. Randomized controlled trial of Tanreqing injection in treatment of acute exacerbation of chronic obstructice pulmonary disease (syndrome of retention of Phlegm-heat in the lung) [J]. Chin J of EBM, 2004; 4(5): 300-336.
61. Liang CY, Wen P, Zheng Y, He G, Fan M, Li WR, Tang SQ, Peng T, Liang GQ, Wang J, Zhang YP. Muti-centre randomized controlled trial of Bi Yuan Shu liquid on patients with chronic nasal sinusitis or nasal polyp after endosoopic sinus surgery[J]. Chin J of EBM, 2004; 4(6): 377-381, 416.
62. Kuang WH, Li J, Li Jing, Wang X, Huang MS, Wang SC, Li T, Huang SZ, Weng YZ, Gao CG, Yan H. Randomized double-blind controlled trial on effectiveness and safety of Jiu Wei Lv Ping particle in the treatment of generalized anxiety disorder[J]. Chin J of EBM, 2004; 4(8): 523-527, 536.
63. Mao B, Zhang RM, Wang L, Chang J, Li TQ. Randomized clinical trial of Lianpu granule in the treatment of common cold (Feng-Re Syndrome) [J]. Chin J of EBM, 2004; 4(10): 677-684.
64. Wang LC, Lei BJ, Liu Li, Liu C, Zhang RM, Li TQ. Jiuweirougan granule in the treatment of chronic hepatitis with hepatic fibrosis: a double-blind randomized controlled trial[J]. Chin J of EBM, 2004; 4(11): 778-782, 793.
65. Chen J, Liu SX, Hu GH, Zhang XY, Xia Y. Gastrodin injection in the treatment of Vertigo: a multi-center single-blind randomized controlled trial[J]. Chin J of EBM, 2004; 4(12): 864-870.

Chinese Journal of Evidence-Based Medicine

Clinical Trials of Traditional Chinese Medicine in China: Status and Evaluation

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