1例老年彌漫性大B細胞淋巴瘤的循證治療_《中國循證醫學雜志》

作者：

林秀芳 , 董碧蓉 , 李峻

四川大學華西醫院,成都,610041;

關鍵詞：

彌漫性大B細胞淋巴瘤老年患者循證治療

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目的　為1例初診的老年彌漫性大B細胞淋巴瘤患者制定循證化療方案.
方法　在充分評估患者病情的基礎上,提出臨床問題,從PubMed(1990年1月～2004年12月)和SUMsearch上進行檢索.
結果　共檢索出關于臨床化療方案的隨機對照試驗11篇及系統評價8篇,其中衛生經濟學評估的系統評價1篇.通過分析檢索結果,并結合患者實際情況,為患者制定出循證治療方案.經5個月的隨訪證實,該方案適合患者.
結論　采用循證醫學的方法為初治的老年彌漫性大B細胞淋巴瘤患者制定化療方案可有效提高治療效果.

引用本文： 林秀芳,董碧蓉,李峻. 1例老年彌漫性大B細胞淋巴瘤的循證治療. 中國循證醫學雜志, 2005, 05(4): 347-349. doi: 復制

1.	Jaffe ES, Harris NL, Stein H, Vardiman JW. World Health Organization classification of tumours: pathology and genetics of tumours of haematopoietic and lymphoid tissues. Lyon, France: International Agency for Research on Cancer. 2001.
2.	Kimby E, Brandt L, Nygren P. A systematic overview of chemotherapy effects in aggressive non-Hodgkin’s lymphoma[J]. Acta Oncol, 2001; 40(2-3): 198-212.
3.	Fisher RI, Gaynor ER, Dahlberg S, Oken MM, Grogan TM, Mize EM, Glick JH, Coltman CA Jr, Miller TP.Comparison of a standard regimen (CHOP) with three intensive chemotherapy regimens for advanced non-Hodgkin’s lymphoma[J]. N Engl J Med, 1993; 328(14): 1 002-1 006.
4.	Tilly H, Lepage E, Coiffier B. A randomized comparison of ACVBP and CHOP in the treatment of advanced aggressive non-Hodgkin’s lymphoma: the LNH93-5 study[J]. Blood, 2000; 96: 832a. abstract.
5.	Kouroukis CT, Browman GP, Esmail R, Meyer RM. Chemotherapy for older patients with newly diagnosed, advanced-stage, aggressive-histology non-Hodgkin lymphoma: a systematic review[J]. Ann Intern Med, 2002; 15; 136(2): 144-152.
6.	No authors listed.Rituximab: new indication. In aggressive non Hodgkin lymphoma: benefits must be confirmed[J].Prescrire Int, 2003; 12(66): 125-126.
7.	W(o")hrer SR. Cyclophosphamide,doxorubicin,vincristine and prednisone (R-CHOP) for treatment of early-stage gastric diffuse large-B-cell lymphoma[J]. Ann Oncol, 2004;15(7): 1 086-1 090.
8.	Portlock CS. Rituximab and CHOP for elderly patients with diffuse large-B-cell lymphoma[J]. Curr Oncol Rep, 2003; 5(5): 357.
9.	Pettengell R, Linch D. Position paper on the therapeutic use of rituximab in CD20-positive diffuse large B-cell non-Hodgkins lymphoma[J]. Br J Haematol, 2003; 121(1): 44-48.
10.	Kimby E, Brandt L, Nygren P, Glimelius B; SBU-group.A systematic overview of chemotherapy effects in aggressive non-Hodgkins lymphoma[J]. Acta Oncol, 2001; 40(2-3): 198-212.
11.	Coiffier B.Immunochemotherapy: the new standard in aggressive non-Hodgkins lymphoma in the elderly[J]. Semin Oncol, 2003; 30(1 Suppl 2): 21-27.
12.	Coiffier B, Lepage E, Briere J.CHOP Chemotherapy plus Rituximab Compared with CHOP Alone in Elderly Patients with Diffuse Large-B-Cell Lymphoma[J]. N Engl J Med, 2002; 346(4): 235-242.
13.	Hannaford P. Rituximab plus CHOP for diffuse large-B-Cell lymphoma[J]. N Engl J Med, 2002; 346(23): 1 830-1 831.
14.	The International Non-Hodgkins Lymphoma Prognostic Factors Project. A predictive model for aggressive non-Hodgkins lymphoma[J]. N Engl J Med, 1993; 329(14): 987-994.
15.	Cancer Therapy Evaluation Program. Common toxicity criteria[M], version2.0. Bethesda, Md.: National Cancer Institute, March 1998.
16.	Knight C, Hind D, Brewer N, Abbott V. Rituximab (MabThera) for aggressive non-Hodgkins lymphoma: systematic review and economic evaluation[J]. Health Technol Assess, 2004; 8(37): iii, ix-xi,1-82.
17.	Heson BD, Horning SJ, Coiffier B. Report of an international workshop to standardize response criteria for non-Hodgkin’s lymphomas[J]. J Clin Oncol, 1999; 17: 1 244. [Erratum,] J Clin Oncol 2000; 18: 2 351.

1. Jaffe ES, Harris NL, Stein H, Vardiman JW. World Health Organization classification of tumours: pathology and genetics of tumours of haematopoietic and lymphoid tissues. Lyon, France: International Agency for Research on Cancer. 2001.
2. Kimby E, Brandt L, Nygren P. A systematic overview of chemotherapy effects in aggressive non-Hodgkin’s lymphoma[J]. Acta Oncol, 2001; 40(2-3): 198-212.
3. Fisher RI, Gaynor ER, Dahlberg S, Oken MM, Grogan TM, Mize EM, Glick JH, Coltman CA Jr, Miller TP.Comparison of a standard regimen (CHOP) with three intensive chemotherapy regimens for advanced non-Hodgkin’s lymphoma[J]. N Engl J Med, 1993; 328(14): 1 002-1 006.
4. Tilly H, Lepage E, Coiffier B. A randomized comparison of ACVBP and CHOP in the treatment of advanced aggressive non-Hodgkin’s lymphoma: the LNH93-5 study[J]. Blood, 2000; 96: 832a. abstract.
5. Kouroukis CT, Browman GP, Esmail R, Meyer RM. Chemotherapy for older patients with newly diagnosed, advanced-stage, aggressive-histology non-Hodgkin lymphoma: a systematic review[J]. Ann Intern Med, 2002; 15; 136(2): 144-152.
6. No authors listed.Rituximab: new indication. In aggressive non Hodgkin lymphoma: benefits must be confirmed[J].Prescrire Int, 2003; 12(66): 125-126.
7. W(o")hrer SR. Cyclophosphamide,doxorubicin,vincristine and prednisone (R-CHOP) for treatment of early-stage gastric diffuse large-B-cell lymphoma[J]. Ann Oncol, 2004;15(7): 1 086-1 090.
8. Portlock CS. Rituximab and CHOP for elderly patients with diffuse large-B-cell lymphoma[J]. Curr Oncol Rep, 2003; 5(5): 357.
9. Pettengell R, Linch D. Position paper on the therapeutic use of rituximab in CD20-positive diffuse large B-cell non-Hodgkins lymphoma[J]. Br J Haematol, 2003; 121(1): 44-48.
10. Kimby E, Brandt L, Nygren P, Glimelius B; SBU-group.A systematic overview of chemotherapy effects in aggressive non-Hodgkins lymphoma[J]. Acta Oncol, 2001; 40(2-3): 198-212.
11. Coiffier B.Immunochemotherapy: the new standard in aggressive non-Hodgkins lymphoma in the elderly[J]. Semin Oncol, 2003; 30(1 Suppl 2): 21-27.
12. Coiffier B, Lepage E, Briere J.CHOP Chemotherapy plus Rituximab Compared with CHOP Alone in Elderly Patients with Diffuse Large-B-Cell Lymphoma[J]. N Engl J Med, 2002; 346(4): 235-242.
13. Hannaford P. Rituximab plus CHOP for diffuse large-B-Cell lymphoma[J]. N Engl J Med, 2002; 346(23): 1 830-1 831.
14. The International Non-Hodgkins Lymphoma Prognostic Factors Project. A predictive model for aggressive non-Hodgkins lymphoma[J]. N Engl J Med, 1993; 329(14): 987-994.
15. Cancer Therapy Evaluation Program. Common toxicity criteria[M], version2.0. Bethesda, Md.: National Cancer Institute, March 1998.
16. Knight C, Hind D, Brewer N, Abbott V. Rituximab (MabThera) for aggressive non-Hodgkins lymphoma: systematic review and economic evaluation[J]. Health Technol Assess, 2004; 8(37): iii, ix-xi,1-82.
17. Heson BD, Horning SJ, Coiffier B. Report of an international workshop to standardize response criteria for non-Hodgkin’s lymphomas[J]. J Clin Oncol, 1999; 17: 1 244. [Erratum,] J Clin Oncol 2000; 18: 2 351.

《中國循證醫學雜志》

1例老年彌漫性大B細胞淋巴瘤的循證治療

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《中國循證醫學雜志》

1例老年彌漫性大B細胞淋巴瘤的循證治療

摘要 全文 圖表 視頻 參考文獻 施引文獻 補充材料

Format

Content

摘要全文圖表視頻參考文獻施引文獻補充材料