目的 調查國內中文期刊發表的中醫藥系統評價/Meta分析文獻的質量。
方法 電子檢索1995年1月到2006年12月的CNKI和CBM,篩選中醫藥的系統評價、Meta分析全文,提取有關中醫特色、治療和對照干預措施的詳細資料進行分析評價,并調查文獻是否采用QUOROM聲明報道結果。
結果 共納入文獻111篇,其中預防、不良反應、危險因素及先兆癥各1篇,理化指標2篇,療效及安全性評價106篇。涉及42個病種,報道腦血管疾病的文獻41篇。干預措施為中醫藥者25篇,針灸者12篇。對照組:未設對照者2篇;未描述對照組干預措施者15篇;陽性藥物對照50篇(其中西藥26篇,中藥12篇,中藥+西藥12篇);空白對照14篇;基礎對照17篇;假針灸、穴位注射等4篇;安慰劑對照5篇;空白對照14篇及“互為對照”4篇。對照組和部分研究治療組的干預措施種類均多。每篇文獻納入RCT 1~35篇不等,其中24個研究納入CCT。111篇文獻在Cochrane協作網注冊者僅14篇。有16篇未對納入RCT進行質量評價,有22篇僅對納入RCT進行簡單不規范的評價。無一篇文獻采用QUOROM聲明報道結果。
結論 應重視提高中醫藥系統評價的質量。根據中醫藥特點,選題范圍不宜過寬,藥物選擇不宜過多,注意中藥的目標適應病證,應重視對干預措施的評價。系統評價應注意由臨床工作者和方法學研究者共同完成,才能做出質量高又具中醫特色的評價。
引用本文: 李廷謙,劉雪梅,張鳴明,馬建昕,杜亮,周宇丹,常靜,王蕾,楊曉楠,王剛,張穎. 中文期刊發表的中醫藥系統評價/ Meta分析現狀調查. 中國循證醫學雜志, 2007, 07(3): 180-188. doi: 復制
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130. | 李玉紅, 張伯禮, 徐宗佩, 等. 脂肪肝中醫藥辨治系統評價. 遼寧中醫雜志, 2002, 29(11): 657~659. |
131. | 商洪才, 張伯禮. 中醫中風病危險因素及先兆癥 (證) 研究系統評價. 中國中醫藥信息雜志, 2002, 9(3): 71~73. |
132. | 李小平, 陳震, 黃雯霞. 中醫藥治療化療后白細胞減少癥的Meta分析. 上海中醫藥雜志, 2003, 37(8): 52~55. |
133. | 吳濱, 溫春毅, 石健林, 等. 針灸戒毒的薈萃分析. 中國針灸, 2003, 23(9): 501~505. |
134. | 吳泰相, 劉關鍵, 張鳴敏, 等. 青蒿素類藥物預防日本血吸蟲感染效果及安全性的系統評價. 中華醫學雜志, 2003, 83(14): 1219~1224. |
135. | 樊均明, 劉連升, 李孜, 等. 黃芪治療成人原發性腎病綜合征Meta-分析. 中藥新藥與臨床藥理, 2003, 14(1): 62~66. |
136. | 王漢蓉, 岑小波, 王莉. 安宮牛黃丸治療肺性腦病的系統評價. 中草藥, 2003, 34(1): 92~73. |
137. | 李國春. 半夏瀉心湯治療慢性胃炎隨機對照試驗的Meta分析. 循證醫學, 2004, 4(1): 14~21. |
138. | 許衛華, 王寶娟, 何羿婷, 等. 以非甾體抗炎藥為對照的中藥治療類風濕性關節炎文獻系統評價. 中國中醫基礎醫學雜志, 2004, 10(1): 20~25. |
139. | 陳礪, 朱春燕, 王小平, 等. 補腎中藥對絕經后骨質疏松癥患者骨密度影響的Meta分析. 中國臨床康復, 2004, 8(30): 6703~6705. |
140. | 冉興無, 李寧, 劉雅. 川芎嗪治療糖尿病周圍神經病變的系統評價. 中國循證醫學雜志, 2004, 4(6): 393~397. |
141. | 陳瑤, 劉鳴. 川芎嗪治療腦梗死: 療效及安全性的系統評價. 中國臨床康復, 2004, 8(7): 1299~1301. |
142. | 趙娜, 董碧蓉, 須晉, 等. 中西醫結合治療嚴重急性呼吸綜合征(SARS) 療效的系統評價. 華西醫學, 2004, 19(3): 353~357. |
143. | 簡訊, 樊均明, 李孜, 等. 川芎嗪治療原發性腎病綜合征的系統評價. 中國循證醫學雜志, 2004, 4(8): 627~633. |
144. | 錢曉路, 袁浩斌, 張美娟. 中醫藥治療壓瘡隨機對照試驗的Meta分析. 護理研究2004, 18(4): 568~570. |
145. | 李慧, 梁偉雄, 郭新峰. 醒腦開竅針法治療中風的Meta分析. 廣州中醫藥大學學報, 2004, 21(3): 215~219. |
146. | 沈朝斌, 顧珺, 林千里, 等. 中醫藥對創傷修復作用的Meta分析. 上海中醫藥雜志, 2004, 38(3): 56~59. |
147. | 孫雪峰, 蘇金環, 葉任高. 中西醫結合治療狼瘡性腎炎的薈萃分析. 中國現代醫學雜志, 2004, 14(17): 23~28. |
148. | 陳力, 杜寶新, 黃燕, 等. 復方丹參注射治療腦中風的Meta-分析. 江西中醫學院學報, 2004, 16(5): 75~78. |
149. | 賀豪杰, 李尚為, 許良智, 等. 中草藥治療輸卵管阻塞性不孕的系統評價. 中國循證醫學雜志, 2004, 4(4): 244~248. |
150. | 彭唯娜, 趙宏, 劉志順, 等. 電針治療血管性癡呆的系統評價. 中國針灸, 2004, 24(5): 297~301. |
151. | 王蕾, 熊澤宇, 王剛, 等. 復方丹參滴丸治療穩定型心絞痛隨機對照試驗的系統評價. 中國中西醫結合雜志, 2004, 24(6): 500~504. |
152. | 李孜, 卿平, 冀玲, 等. 大黃治療慢性腎功能衰竭的系統評價. 中國循證醫學雜志 2004, 4(7): 468~473. |
153. | 張敏州, 王磊, 陳伯鈞, 等. 復方丹參滴丸治療穩定型心絞痛Meta分析. 中西醫結合心腦血管病雜志, 2004, 2(6): 311~314. |
154. | 王雪, 李素霞, 祝三平, 等. 福康片治療阿片類戒斷癥狀的療效及安全性評價. 中國循證醫學雜志, 2004, 4(8): 545~549. |
155. | 王紅靜, 黃倩, 安寒, 等. 中草藥治療子宮內膜異位癥的系統評價. 中國循證醫學雜志, 2004, 4(9): 602~608. |
156. | 賀豪杰, 許良智, 李尚為, 等. 中草藥治療女性免疫性不孕的系統評價. 中國循證醫學雜志, 2004, 4(9): 609~614. |
157. | 王林, 周仕軼, 邵繼春, 等. 補腎活血類中藥復方治療良性前列腺增生的系統評價. 中華男科學雜志, 2004, 10(10): 785~789. |
158. | 聶廣寧, 王小云, 楊洪艷, 等. 中醫藥治療更年期綜合征的系統評價. 中醫藥通報, 2004, 3(5): 10~16. |
159. | 周賢剛, 王宏偉, 余廣彬, 等. 麝香保心丸治療冠心病心絞痛的Meta-分析. 中成藥, 2004, (26): 1~6. |
160. | 馬凌, 翁燕娜, 肖昕. 中醫藥聯合化療治療進展期非小細胞肺癌近期療效和生存質量的META分析. 中華實用中西醫雜志, 2004, 4(17): 709~712. |
161. | 陳衛平, 呂紅, 舒志軍. 玉屏風散與T細胞亞型表達的Meta分析. 上海中醫藥雜志, 2004, 38(11): 59~61. |
162. | 田浩明, 魏東, 賈海燕. 葛根素治療糖尿病周圍神經病變的系統評價. 中國循證醫學雜志, 2004, 4(8): 556~569. |
163. | 吳泰相, 劉保延, 劉關鍵, 等. 中西醫結合治療SARS療效的系統評價. 中國循證醫學雜志, 2004, 4(4): 226~238. |
164. | 劉曉雁, 賴世隆, 郭新峰, 等. 參麥注射液輔助腫瘤化療的系統評價. 中國循證醫學雜志, 2005, 5(1): 22~28. |
165. | 李寧, 吳濱, 王成偉, 等. 針灸治療失眠癥隨機對照試驗的系統評價. 中國針灸, 2005, 25(1): 7~10. |
166. | 謝雁鳴, 朱蕓茵, 吳泰相. 中醫藥治療絕經后骨質疏松的療效及安全性系統評價. 中國循證醫學雜志, 2005, 5(1): 29~34. |
167. | 吳波, 劉鳴, 張世洪. 丹參類藥物治療急性缺血性腦卒中的系統評價. 中國循證醫學雜志, 2005, 5(2): 101~105. |
168. | 陳弼滄, 吳秋英, 王麗英, 等. 葛根素注射液治療糖尿病周圍神經病變的Meta分析. 福建中醫藥, 2005, 36(1): 32~34. |
169. | 李漾, 羅純. 針刺治療緊張性頭痛療效的系統評價. 中國循證醫學雜志, 2005, 5(2): 117~124. |
170. | 何俐, 周沐科, 周東, 等. 針灸治療Bell’s面癱療效的系統評價. 中國循證醫學雜志, 2005, 5(2): 106~109. |
171. | 劉宇, 吳勝丹, 李瑛. 中藥治療絕經后骨質疏松癥的系統評價. 海南醫學, 2005, 16(2): 136~137. |
172. | 劉云霞, 王浩英, 龐春坤, 等. 中草藥治療脂肪肝隨機對照試驗的系統評價. 循證醫學, 2005, 5(1): 29~32. |
173. | 曹文齋, 蘭德, 張婷, 等. 燈盞花注射液治療心絞痛療效的系統評價. 中國循證醫學雜志, 2005, 5(4): 317~322. |
174. | 郝艷會, 洪軍, 寇長貴, 等. 中西醫結合與單純西醫治療SARS的Meta分析. 中國公共衛生, 2005, 21(5): 525~526. |
175. | 黃宇虹, 胡鏡清, 高秀梅, 等. 復方丹參注射液配伍黃芪注射液治療冠心病療效Meta分析. 天津中醫藥, 2005, 22(5): 375~377. |
176. | 陳軍, 陳輝揚, 劉志承, 等. 茵梔黃注射對黃疸型病毒性肝炎的退黃效果與安全性的系統評價. 中國循證醫學雜志, 2005, 5(6): 461~465. |
177. | 劉向前, 姚共和, 楊少鋒, 等. 以NSAIDs為對照中藥治療膝關節骨關節炎文獻的系統評價. 中醫藥學刊, 2005, 23(6): 1008~1012. |
178. | 羅勝, 羅思文. 針灸治療腰椎間盤突出癥的系統分析. 針灸臨床雜志, 2005, 21(6): 10~14. |
179. | 許風雷, 高麗霞, 吳泰相, 等. 醒腦靜注射液治療腦梗塞臨床療效及安全性隨機對照試驗的系統評價. 中國循證醫學雜志, 2005, 5(7): 549~565. |
180. | 岳冀蓉, 吳泰相, 董碧蓉. 智靈湯治療血管性癡呆的系統評價. 中國循證醫學雜志, 2005, 5(9): 692~695. |
181. | 李博, 李峰, 吳泰相. 參附脫毒膠囊治療阿片類急性戒斷綜合征的系統評價. 中國循證醫學雜志, 2005, 5(9): 684~691. |
182. | 于金娜, 劉保延, 劉志順, 等. 針刺治療經前期綜合征的臨床療效和安全性評價. 中國針灸, 2005, 25(6): 377~382. |
183. | 朱泉, 江魏. 中醫補腎法提高男性血清睪酮水平的研究. 醫學信息, 2005, 18(9): 1153~1155. |
184. | 張世洪, 劉鳴, 李林. 針刺治療急性腦卒中隨機或半隨機對照試驗的Cochrane系統評價. 中國臨床康復, 2005, 9(9): 108~110. |
185. | 劉建平, Eric Manheimer, 施毅, 等. 中西醫結合治療SARS的系統評價與Meta-分析. 中國中西醫結合雜志, 2005, 25(12): 1082~1088. |
186. | 劉增巍, 張星星. 中藥治療胃癌前病變療效的薈萃分析. 現代中西醫結合雜志, 2005, 14(21): 2818~2820. |
187. | 張偉, 張心月, 王新東, 等. 魚腥草注射液治療呼吸系統感染的Meta分析. 中國藥學雜志, 2005, 40(21): 1674~1677. |
188. | 周賢剛, 楊闖, 楊麗霞, 等. 中藥穴位貼敷治療面癱的Meta-分析. 中國針灸, 2005, 25(11): 797~802. |
189. | 李永健, 陳紅風, 邸若虹, 等. 中醫藥治療乳腺增生病隨機對照臨床試驗系統評價. 中國中醫藥信息雜志, 2005, 12(12): 98~99. |
190. | 李勉珊, 王杰松, 李保衛, 等. 葛根素注射液治療突發性耳聾的Meta分析. 中國藥房, 2006, 17(1): 44~46. |
191. | 方潤權, 黃雪梅. 杏丁注射液改善急性腦梗死患者運動功能的系統評價. 中國現代醫藥雜志, 2006, 8(3): 32~34. |
192. | 王麗平, 解越. 針灸治療卒中后吞咽困難的系統評價. 中國針灸, 2006, 26(2): 141~146. |
193. | 王昕, 朱云茵, 胡立勝. 中醫藥治療血管性癡呆的系統評價. 南京中醫藥大學學報, 2006, 22(3): 181~182. |
194. | 王杰松, 張俊虎, 胡慧淵, 等. 三七總皂苷和復方丹參注射液治療腦梗死的Meta分析. 中國醫院藥學雜志, 2006, 26(3): 317-319. |
195. | 劉為民, 劉保延, 謝雁鳴, 等. 疏血通注射液治療腦梗塞的系統評價. 中國循證醫學雜志, 2006, 6(4): 261~266. |
196. | 王衛霞, 陳可冀. 血脂康膠囊治療高脂血癥有效性和安全性的系統評價. 中國循證醫學雜志, 2006, 6(5): 352-360. |
197. | 楊光, 王新卷. 電針治療頸椎病療效的系統評價. 北京中醫, 2005, 25(7): 433~435. |
198. | 譚燕, 劉鳴, 吳波. 葛根素治療急性腦梗死的系統評價. 中國循證醫學雜志, 2006, 6(7): 494~499. |
199. | 鄭明, 蘇培華. 支氣管哮喘中醫藥治療性研究文獻的系統評價. 醫藥產業資訊, 2006, 3(9): 22~24. |
200. | 姜挺, 夏冰, 李春, 等. 中藥保留灌腸治療潰瘍性結腸炎療效的系統評價. 醫藥導報, 2006, 25(10): 1016~1019. |
201. | 許風雷, 環文英, 吳泰相, 等. 冬蟲夏草治療慢性腎病臨床療效的系統評價. 中國循證醫學雜志, 2006, 6(11): 804~808. |
202. | 李可建. 燈盞花制劑治療缺血性中風急性期隨機對照試驗的系統評價. 中國醫藥導刊, 2006, 8(1): 41~44. |
203. | 李可建. 葛根素治療缺血性中風急性期隨機對照試驗的系統評價. 山東中醫藥大學學報, 2006, 30(2): 120~124. |
204. | 李可建. 補陽還五湯及其中成藥治療缺血性中風急性期隨機對照試驗的系統評價. 中成藥, 2006, 28(1): 58~63. |
205. | 李可建. 醒腦靜注射液治療缺血性中風急性期隨機對照試驗的系統評價. 泰山醫學院學報, 2006, 27(4): 310~312. |
206. | 李可建. 參麥注射液治療缺血性中風急性期隨機對照試驗的系統評價. 中醫藥學報, 2006, 34(4): 4~7. |
207. | 李可建. 安宮牛黃丸制劑治療缺血性中風急性期隨機對照試驗的系統評價. 陜西中醫, 2006, 27(7): 804~807. |
208. | 李可建. 脈絡寧注射液治療缺血性中風急性期隨機對照試驗的系統評價. 中華中醫藥雜志, 2006, 21(8): 471~474. |
209. | 李可建. 通心絡膠囊治療缺血性卒中急性期隨機對照試驗的Meta分析. 醫藥導報, 2006, 25(9): 893~896. |
210. | 李可建. 蚓激酶膠囊治療缺血性中風急性期隨機對照試驗的系統評價. 中醫研究, 2006, 19(9): 24~28. |
211. | 李可建. 川芎嗪注射液治療缺血性中風急性期隨機對照實驗的系統評價. 時珍國醫國藥, 2006, 17(10): 1874~1876. |
212. | 李可建. 對腦心通膠囊治療缺血性中風急性期隨機對照研究的系統評價. 山東醫藥, 2006, 46(14): 35~37. |
213. | 李可建. 水蛭治療缺血性中風急性期隨機對照試驗的系統評價. 現代中西醫結合雜志, 2006, 15(17): 2311~2312, 2314. |
214. | 李可建. 補陽還五湯治療缺血性中風急性期隨機對照試驗的系統評價研究. 云南中醫學院學報, 2006, 29(6): 24~28. |
215. | 李可建. 刺五加注射液治療缺血性中風急性期隨機對照試驗的系統評價. 中成藥, 2006, 28(10): 1458~1461. |
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