Progress of Non-Invasive Arterial Measurements and Evaulation of Cardiovascular Injury of OSAHS_Chinese Journal of Respiratory and Critical Care Medicine

Authors：

WANG Yan , ZHANG Xiujuan , LI Qingyun

Department of Respiratory Medicine，Ruijin Hospital，Shanghai jiaotong University.Shanghai 200025,China;

Corresponding?author：

Keywords：

動脈; 無創檢測技術; 阻塞性睡眠呼吸暫停低通氣綜合征; 心血管損傷; ; 評估

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阻塞性睡眠呼吸暫停低通氣綜合征( OSAHS) 是心血管疾病的獨立危險因素[1,2 ]。睡眠過程中反復發生氧飽和度降低和頻繁覺醒是心血管損傷的病理生理基礎。OSAHS 血管損害的早期改變可表現為血管僵硬度增加, 對亞臨床血管病變患者開展早期動脈彈性功能檢測及早進行干預, 可有效預防心血管疾病的發生。本文就常用的無創動脈硬化檢測 lt;br / gt;技術及其對OSAHS 心血管損傷的評估相關研究進展進行綜述。

Citation： WANG Yan,ZHANG Xiujuan,LI Qingyun. Progress of Non-Invasive Arterial Measurements and Evaulation of Cardiovascular Injury of OSAHS. Chinese Journal of Respiratory and Critical Care Medicine, 2010, 9(3): 329-331. doi: Copy

1.	Lorenzi-Filho G，Drager LF.Obstructive sleep apnea and atherosclerosis：a new paradigm.Am J Respir Crit Care Med，2007，175：1219-1221.
2.	王菡僑，何權瀛.阻塞性睡眠呼吸暫停綜合征與高血壓.中國呼吸與危重監護雜志，2008，7：313-317.
3.	O’Leary DH，Polak JF，Kronmal RA，et al.Carotidartery intima and media thickness as a risk factor for myocardial infarction and stroke in older adults.N Engl J Med，1999，340：34-42.
4.	Takiuchi S，Kamide K，Miwa Y，et al.Diagnostic value of carotid intima-media thickness and plaque score for predicting target organ damage in patients with essential hypertension.J Hum Hypertens，2004，18：17-23.
5.	寶輝，苗懿德，張穎.老年人血尿酸水平與頸動脈粥樣硬化程度的相關性研究.中華全科醫師雜志，2005，4：13-16.
6.	萬里凱，王小燕，張琴，等.年輕人頸動脈內中膜厚度與血壓及QT離散度的相關性研究.中華超聲影像學雜志，2008，17：858-860.
7.	劉俊，姚歡.高血壓病患者頸動脈內膜中層厚度與靜息心率的關系.醫師進修雜志，2005，28：39-42.
8.	李振光，伍期專，唐朝樞，等.動脈粥樣硬化患者頸動脈內膜中層厚度與血漿溶血磷脂酸含量的變化.中華醫學雜志，2004，84：1071-1072.
9.	匡鼎偉，丁峰，薛駿，等.維持性血透患者頸動脈內膜中層厚度增厚及其影響因素分析.中華腎臟病雜志，2005，21：577-581.
10.	王云開，魏云峰，王夢洪，等.頸動脈內膜中層增厚患者血清基質金屬蛋白酶-9、可溶性P-選擇素和高敏C-反應蛋白變化的研究.中國綜合臨床，2008，24：1241-1243.
11.	Kiykim AA，Camsari A，Kahraman S，et al.Increased incidence of carotid artery wall changes and associated variables in hemodialysis patients without symptomatic cardiovascular disease.Yousei Med J，2004，45：247-254.
12.	王新，張磊，饒小胖，等.頸動脈內膜中層厚度影響因素的研究進展.國外醫學內分泌學分冊，2004，24：423-424.
13.	World Health Organization.International society of hypertension guidelines for the management of hypertension.Guidelines Subcommittee.J Hypertens，1999，17：151-183.
14.	Hopkins KD，Lehmann ED，Gosling RG.Aortic compliance measurements：a non-invasive indicator of atherosclerosis? Lancet，1994，343：1447.
15.	Filipovský J，Tichá M，Cífková R，et al.Large artery stiffness and pulse wave reflection：results of a population-based study.Blood Press，2005，14：45-52.
16.	Laurent S，Boutouyrie P，Asmar R，et al.Aortic stiffness is an independent predictor of all-cause and cardiovascular mortality in hypertensive patients.Hypertension，2001，37：1236-1241.
17.	Blacher J，Guerin AP，Pannier B，et al.Impact of aortic stiffness on survival in end stage renal disease.Circulation，1999，99：2434-2439.
18.	Cruickshank K，Riste L，Anderson SG，et al.Aortic pulse-wave velocity and its relationship to mortality in diabetes and glucose intolerance：an integrated index of vascular function? Circulation，2002，106：2085-2090.
19.	Vaitkevicius PV，Fleg JL，Engel JH，et al.Effects of age and aerobic capacity on arterial stiffness in healthy adults.Circulation，1993，88：1456-1462.
20.	Lehmann ED，Watts GF，Gosling RG.Aortic distensibility and hypercholesterolemia.Lancet，1992，340：1171-1172.
21.	Lehmann ED，Gosling RG，Sonksen PH.Arterial wall compliance in diabetes.Diabet Med，1992，9：114-119.
22.	Rajkumar C，Kingwell BA，Cameron JD，et al.Hormonal therapy increases arterial compliance in postmenopausal women.J Am Coll Cardiol，1997，30：350-356.
23.	孫衛平，吳永全，李覺，等.脈搏波傳導速度與冠心病心功能不全的相關性.中華內科雜志，2008，47：382-384.
24.	Okura T，Watanabe S，Kurata M，et al.Relationship between cardio-ankle vascular index （CAVI） and carotid atherosclerosis in patients with essential hypertension.Hypertens Res，2007，30：335-340.
25.	Satoh N，Shimatsu A，Kato Y，et al.Evaluation of the cardio-ankle Index，a new indicator of arterial stiffness independent of blood pressure，in obesity and metabolic syndrome.Hypertense Res，2008，31：1921-1930.
26.	Takenaka T，Hoshi H，Kato N，et al.Cardioankle vascular index to screen cardiovascular diseases in patients with end-stage renal diseases.J Atheroscler Thromb，2008，15：339-344.
27.	Masugata H，Senda S，Himoto T，et al.Detection of increased arterial stiffness in a patient with early stage of large vessel vasculitis by measuring cardio-ankle vascular index.Tohoku J Exp Med，2009，219：101-105.
28.	Sakane K，Miyoshi T，Doi M，et al.Association of new arterial stiffness parameter，the cardio-ankle vascular index，with left ventricular diastolic function.J Atheroscler Thromb，2008，15：261-268.
29.	Shiral K，Utiro J，Otsuka K，et al.A novel blood-pressure-independent arterial wall stiffness parameter：cardio-ankle vascular index.J Atherosoler Thromb，2006，13：101-107.
30.	Yamamoto N，Yamanaka G，Ishikawa M，et al.Cardio-ankle vascular index as a predictor of cogonitive impairment in community-dwelling elderly people：four-year follow-up.Dement Geriatr Cogn Disord，2009，28：153-158.
31.	Kadota K，Takamura N，Aoyagi K，et al.Availability of cardio-ankle vascular index （CAVI） as a screening tool for atherosclerosis.Circ J，2008，72：304-308.
32.	Anderson AD，Uehata A，Gerhard MD，et al.Close relationship of endothelial function in the human coronary and peripheral circulations.Am Coll Cardiol，1995，26：1235-1241.
33.	賈鋒鵬，雷寒，覃數.無癥狀心肌缺血與高敏C反應蛋白和內皮功能失調.中華內科雜志，2007，46：919-922.
34.	林金秀，楊霞，鄭小蓉，等.高血壓合并代謝綜合征患者血管功能及靶器官損害的變化.中華心血管雜志，2007，35：710-714.
35.	Kumagai T，Kasai T，Kato M，et al.Establishment of the cardio-ankle vascular Index in patients with obstructive sleep apnea.Chest，2009，136：779-786.
36.	Bayram NA，Ciftci B，Keles T，et al.Endothelial function in normotensive men with obstructive sleep apnea before and 6 months after CPAP treatment.Sleep，2009，32：1257-1263.
37.	Tanriverdi H，Evrengul H，Kara CO，et al.Aortic stiffness，flow-mediated dilatation and carotid intima-media thickness in obstructive sleep apnea：non-invasive indicators of atherosclerosis.Respiration，2006，73：741-750.
38.	田建立，張蘊，王錚，等.阻塞性睡眠呼吸暫停低通氣綜合征患者動脈粥樣硬化無創檢測指標分析.中華結核和呼吸雜志，2006，6：395-398.
39.	Amra B，Karbasi E，Hashemi M，et al.Endothelial dysfunction in patients with obstructive sleep apnoea independent of metabolic syndrome.Ann Acad Med Singapore，2009，38：461-464.

1. Lorenzi-Filho G，Drager LF.Obstructive sleep apnea and atherosclerosis：a new paradigm.Am J Respir Crit Care Med，2007，175：1219-1221.
2. 王菡僑，何權瀛.阻塞性睡眠呼吸暫停綜合征與高血壓.中國呼吸與危重監護雜志，2008，7：313-317.
3. O’Leary DH，Polak JF，Kronmal RA，et al.Carotidartery intima and media thickness as a risk factor for myocardial infarction and stroke in older adults.N Engl J Med，1999，340：34-42.
4. Takiuchi S，Kamide K，Miwa Y，et al.Diagnostic value of carotid intima-media thickness and plaque score for predicting target organ damage in patients with essential hypertension.J Hum Hypertens，2004，18：17-23.
5. 寶輝，苗懿德，張穎.老年人血尿酸水平與頸動脈粥樣硬化程度的相關性研究.中華全科醫師雜志，2005，4：13-16.
6. 萬里凱，王小燕，張琴，等.年輕人頸動脈內中膜厚度與血壓及QT離散度的相關性研究.中華超聲影像學雜志，2008，17：858-860.
7. 劉俊，姚歡.高血壓病患者頸動脈內膜中層厚度與靜息心率的關系.醫師進修雜志，2005，28：39-42.
8. 李振光，伍期專，唐朝樞，等.動脈粥樣硬化患者頸動脈內膜中層厚度與血漿溶血磷脂酸含量的變化.中華醫學雜志，2004，84：1071-1072.
9. 匡鼎偉，丁峰，薛駿，等.維持性血透患者頸動脈內膜中層厚度增厚及其影響因素分析.中華腎臟病雜志，2005，21：577-581.
10. 王云開，魏云峰，王夢洪，等.頸動脈內膜中層增厚患者血清基質金屬蛋白酶-9、可溶性P-選擇素和高敏C-反應蛋白變化的研究.中國綜合臨床，2008，24：1241-1243.
11. Kiykim AA，Camsari A，Kahraman S，et al.Increased incidence of carotid artery wall changes and associated variables in hemodialysis patients without symptomatic cardiovascular disease.Yousei Med J，2004，45：247-254.
12. 王新，張磊，饒小胖，等.頸動脈內膜中層厚度影響因素的研究進展.國外醫學內分泌學分冊，2004，24：423-424.
13. World Health Organization.International society of hypertension guidelines for the management of hypertension.Guidelines Subcommittee.J Hypertens，1999，17：151-183.
14. Hopkins KD，Lehmann ED，Gosling RG.Aortic compliance measurements：a non-invasive indicator of atherosclerosis? Lancet，1994，343：1447.
15. Filipovský J，Tichá M，Cífková R，et al.Large artery stiffness and pulse wave reflection：results of a population-based study.Blood Press，2005，14：45-52.
16. Laurent S，Boutouyrie P，Asmar R，et al.Aortic stiffness is an independent predictor of all-cause and cardiovascular mortality in hypertensive patients.Hypertension，2001，37：1236-1241.
17. Blacher J，Guerin AP，Pannier B，et al.Impact of aortic stiffness on survival in end stage renal disease.Circulation，1999，99：2434-2439.
18. Cruickshank K，Riste L，Anderson SG，et al.Aortic pulse-wave velocity and its relationship to mortality in diabetes and glucose intolerance：an integrated index of vascular function? Circulation，2002，106：2085-2090.
19. Vaitkevicius PV，Fleg JL，Engel JH，et al.Effects of age and aerobic capacity on arterial stiffness in healthy adults.Circulation，1993，88：1456-1462.
20. Lehmann ED，Watts GF，Gosling RG.Aortic distensibility and hypercholesterolemia.Lancet，1992，340：1171-1172.
21. Lehmann ED，Gosling RG，Sonksen PH.Arterial wall compliance in diabetes.Diabet Med，1992，9：114-119.
22. Rajkumar C，Kingwell BA，Cameron JD，et al.Hormonal therapy increases arterial compliance in postmenopausal women.J Am Coll Cardiol，1997，30：350-356.
23. 孫衛平，吳永全，李覺，等.脈搏波傳導速度與冠心病心功能不全的相關性.中華內科雜志，2008，47：382-384.
24. Okura T，Watanabe S，Kurata M，et al.Relationship between cardio-ankle vascular index （CAVI） and carotid atherosclerosis in patients with essential hypertension.Hypertens Res，2007，30：335-340.
25. Satoh N，Shimatsu A，Kato Y，et al.Evaluation of the cardio-ankle Index，a new indicator of arterial stiffness independent of blood pressure，in obesity and metabolic syndrome.Hypertense Res，2008，31：1921-1930.
26. Takenaka T，Hoshi H，Kato N，et al.Cardioankle vascular index to screen cardiovascular diseases in patients with end-stage renal diseases.J Atheroscler Thromb，2008，15：339-344.
27. Masugata H，Senda S，Himoto T，et al.Detection of increased arterial stiffness in a patient with early stage of large vessel vasculitis by measuring cardio-ankle vascular index.Tohoku J Exp Med，2009，219：101-105.
28. Sakane K，Miyoshi T，Doi M，et al.Association of new arterial stiffness parameter，the cardio-ankle vascular index，with left ventricular diastolic function.J Atheroscler Thromb，2008，15：261-268.
29. Shiral K，Utiro J，Otsuka K，et al.A novel blood-pressure-independent arterial wall stiffness parameter：cardio-ankle vascular index.J Atherosoler Thromb，2006，13：101-107.
30. Yamamoto N，Yamanaka G，Ishikawa M，et al.Cardio-ankle vascular index as a predictor of cogonitive impairment in community-dwelling elderly people：four-year follow-up.Dement Geriatr Cogn Disord，2009，28：153-158.
31. Kadota K，Takamura N，Aoyagi K，et al.Availability of cardio-ankle vascular index （CAVI） as a screening tool for atherosclerosis.Circ J，2008，72：304-308.
32. Anderson AD，Uehata A，Gerhard MD，et al.Close relationship of endothelial function in the human coronary and peripheral circulations.Am Coll Cardiol，1995，26：1235-1241.
33. 賈鋒鵬，雷寒，覃數.無癥狀心肌缺血與高敏C反應蛋白和內皮功能失調.中華內科雜志，2007，46：919-922.
34. 林金秀，楊霞，鄭小蓉，等.高血壓合并代謝綜合征患者血管功能及靶器官損害的變化.中華心血管雜志，2007，35：710-714.
35. Kumagai T，Kasai T，Kato M，et al.Establishment of the cardio-ankle vascular Index in patients with obstructive sleep apnea.Chest，2009，136：779-786.
36. Bayram NA，Ciftci B，Keles T，et al.Endothelial function in normotensive men with obstructive sleep apnea before and 6 months after CPAP treatment.Sleep，2009，32：1257-1263.
37. Tanriverdi H，Evrengul H，Kara CO，et al.Aortic stiffness，flow-mediated dilatation and carotid intima-media thickness in obstructive sleep apnea：non-invasive indicators of atherosclerosis.Respiration，2006，73：741-750.
38. 田建立，張蘊，王錚，等.阻塞性睡眠呼吸暫停低通氣綜合征患者動脈粥樣硬化無創檢測指標分析.中華結核和呼吸雜志，2006，6：395-398.
39. Amra B，Karbasi E，Hashemi M，et al.Endothelial dysfunction in patients with obstructive sleep apnoea independent of metabolic syndrome.Ann Acad Med Singapore，2009，38：461-464.

Chinese Journal of Respiratory and Critical Care Medicine

Progress of Non-Invasive Arterial Measurements and Evaulation of Cardiovascular Injury of OSAHS

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