睡眠呼吸障礙與冠心病及心律失常_《中國呼吸與危重監護雜志》

作者：

王蓓

山西醫科大學第二附屬醫院睡眠中心（山西太原 030001）;

關鍵詞：

睡眠呼吸障礙冠心病心律失常

視頻：

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睡眠呼吸障礙（sleep breathing disorders，SDB）是一種常見病、多發病，其主要類型是阻塞性睡眠呼吸暫停綜合征（OSAS），特點是夜間睡眠過程中上氣道完全或部分阻塞及呼吸中樞驅動降低導致呼吸暫停及低通氣，產生慢性間歇性低氧、反復微覺醒、睡眠結構異常、自主神經功能紊亂等。OSAS近年已公認是一種全身性疾病，它可引起或加重許多疾病,美國心臟協會/美國心臟病學基金會（AHA/ACCF）聯合發表了《睡眠呼吸暫停與心血管疾病的科學共識》。為了進一步認識兩者之間的關系，提升OSAS及相關疾病防控水平，中華醫學會呼吸病分會睡眠學組與心血管病學組就SDB與心血管疾病相關問題達成共識，為多學科聯合防治SDB提供了科學依據。

引用本文： 王蓓. 睡眠呼吸障礙與冠心病及心律失常. 中國呼吸與危重監護雜志, 2010, 9(1): 2-4. doi: 復制

1.	Young T,Evans L,Finn L,et al.Estimation of the clinically diagnosed proportion of sleep apnea syndrome in middle-aged men and women.Sleep,1997,20:705-706.
2.	Bixler EO,Vgontzas AN,Ten Have T,et al.Effects of age on sleep apnea in men: I.Prevalence and severity.Am J Respir Crit Care Med,1998,157:144-148.
3.	Hu FB,Willett WC,Manson JE,et al.Snoring and risk of cardiovascular disease in women. J Am Coll Cardiol,2000,35:308-313.
4.	Nieto FJ,Young TB,Lind BK,et al.Association of sleep-disordered breathing,sleep apnea,and hypertension in a large community-based study.Sleep Heart Health Study.JAMA,2000,283:1829-1836.
5.	Elmasry A,Lindberg E,Berne C,et al.Sleep-disordered breathing and glucose metabolism in hypertensive men: a population-based study.J Intern Med,2001,249:153-161.
6.	Hu FB,Willett WC,Colditz GA,et al.Prospective study of snoring and risk of hypertension in women.Am J Epidemiol,1999,150:806-816.
7.	Wilcox I,McNamara SG,Collins FL,et al."Syndrome Z": the interaction of sleep apnoea,vascular risk factors and heart disease.Thorax,1998,53:S25-S28.
8.	He J,Kryger MH,Zorick FJ,et al.Mortality and apnea index in obstructive sleep apnea.Experience in 385 male patients.Chest,1988,94:9-14.
9.	Ayas NT,White DP,Manson JE,et al.A prospective study of sleep duration and coronary heart disease in women.Arch Intern Med,2003;163:205-209.
10.	Haas DC,Foster GL,Nieto FJ,et al.Age-dependent associations between sleep-disordered breathing and hypertension: importance of discriminating between systolic/diastolic hypertension and isolated systolic hypertension in the Sleep Heart Health Study.Circulation,2005,111:614-621.
11.	Gami AS,Hodge DO,Herges RM,et al.Obstructive sleep apnea,obesity,and the risk of incident atrial fibrillation.J Am Coll Cardiol,2007,49:565-571.
12.	Lavie P,Lavie L,Herer P.All-cause mortality in males with sleep apnoea syndrome: declining mortality rates with age.Eur Respir J,2005,25:514-520.
13.	Somers VK,Dyken ME,Mark AL,et al.Sympathetic-nerve activity during sleep in normal subjects.N Engl J Med,1993;328:303-307.
14.	Somers VK,Mark AL,Zavala DC,et al.Influence of ventilation and hypocapnia on sympathetic nerve responses to hypoxia in normal humans.J Appl Physiol,1989,67:2095-2100.
15.	Narkiewicz K,van de Borne PJ,Cooley RL,et al.Sympathetic activity in obese subjects with and without obstructive sleep apnea.Circulation,1998,98:772-776.
16.	Copie X,Hnatkova K,Staunton A,et al.Predictive power of increased heart rate versus depressed left ventricular ejection fraction and heart rate variability for risk stratification after myocardial infarction.Results of a two-year follow-up study.J Am Coll Cardiol,1996,27:270-276.
17.	Phillips BG,Narkiewicz K,Pesek CA,et al.Effects of obstructive sleep apnea on endothelin-1 and blood pressure.J Hypertens,1999,17:61-66.
18.	Svatikova A,Wolk R,Shamsuzzaman AS,et al.Serum amyloid a in obstructive sleep apnea..Circulation,2003,108:1451-1454.
19.	Shamsuzzaman AS,Winnicki M,Lanfranchi P,et al.Elevated C-reactive protein in patients with obstructive sleep apnea.Circulation,2002,105:2462-2464.
20.	.Quan SF,Howard BV,Iber C,et al.The Sleep Heart Health Study: design,rationale,and methods.Sleep,1997,20:1077-1085.

1. Young T,Evans L,Finn L,et al.Estimation of the clinically diagnosed proportion of sleep apnea syndrome in middle-aged men and women.Sleep,1997,20:705-706.
2. Bixler EO,Vgontzas AN,Ten Have T,et al.Effects of age on sleep apnea in men: I.Prevalence and severity.Am J Respir Crit Care Med,1998,157:144-148.
3. Hu FB,Willett WC,Manson JE,et al.Snoring and risk of cardiovascular disease in women. J Am Coll Cardiol,2000,35:308-313.
4. Nieto FJ,Young TB,Lind BK,et al.Association of sleep-disordered breathing,sleep apnea,and hypertension in a large community-based study.Sleep Heart Health Study.JAMA,2000,283:1829-1836.
5. Elmasry A,Lindberg E,Berne C,et al.Sleep-disordered breathing and glucose metabolism in hypertensive men: a population-based study.J Intern Med,2001,249:153-161.
6. Hu FB,Willett WC,Colditz GA,et al.Prospective study of snoring and risk of hypertension in women.Am J Epidemiol,1999,150:806-816.
7. Wilcox I,McNamara SG,Collins FL,et al."Syndrome Z": the interaction of sleep apnoea,vascular risk factors and heart disease.Thorax,1998,53:S25-S28.
8. He J,Kryger MH,Zorick FJ,et al.Mortality and apnea index in obstructive sleep apnea.Experience in 385 male patients.Chest,1988,94:9-14.
9. Ayas NT,White DP,Manson JE,et al.A prospective study of sleep duration and coronary heart disease in women.Arch Intern Med,2003;163:205-209.
10. Haas DC,Foster GL,Nieto FJ,et al.Age-dependent associations between sleep-disordered breathing and hypertension: importance of discriminating between systolic/diastolic hypertension and isolated systolic hypertension in the Sleep Heart Health Study.Circulation,2005,111:614-621.
11. Gami AS,Hodge DO,Herges RM,et al.Obstructive sleep apnea,obesity,and the risk of incident atrial fibrillation.J Am Coll Cardiol,2007,49:565-571.
12. Lavie P,Lavie L,Herer P.All-cause mortality in males with sleep apnoea syndrome: declining mortality rates with age.Eur Respir J,2005,25:514-520.
13. Somers VK,Dyken ME,Mark AL,et al.Sympathetic-nerve activity during sleep in normal subjects.N Engl J Med,1993;328:303-307.
14. Somers VK,Mark AL,Zavala DC,et al.Influence of ventilation and hypocapnia on sympathetic nerve responses to hypoxia in normal humans.J Appl Physiol,1989,67:2095-2100.
15. Narkiewicz K,van de Borne PJ,Cooley RL,et al.Sympathetic activity in obese subjects with and without obstructive sleep apnea.Circulation,1998,98:772-776.
16. Copie X,Hnatkova K,Staunton A,et al.Predictive power of increased heart rate versus depressed left ventricular ejection fraction and heart rate variability for risk stratification after myocardial infarction.Results of a two-year follow-up study.J Am Coll Cardiol,1996,27:270-276.
17. Phillips BG,Narkiewicz K,Pesek CA,et al.Effects of obstructive sleep apnea on endothelin-1 and blood pressure.J Hypertens,1999,17:61-66.
18. Svatikova A,Wolk R,Shamsuzzaman AS,et al.Serum amyloid a in obstructive sleep apnea..Circulation,2003,108:1451-1454.
19. Shamsuzzaman AS,Winnicki M,Lanfranchi P,et al.Elevated C-reactive protein in patients with obstructive sleep apnea.Circulation,2002,105:2462-2464.
20. .Quan SF,Howard BV,Iber C,et al.The Sleep Heart Health Study: design,rationale,and methods.Sleep,1997,20:1077-1085.

《中國呼吸與危重監護雜志》

睡眠呼吸障礙與冠心病及心律失常

摘要 全文 圖表 視頻 參考文獻 施引文獻 補充材料

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《中國呼吸與危重監護雜志》

睡眠呼吸障礙與冠心病及心律失常

摘要 全文 圖表 視頻 參考文獻 施引文獻 補充材料

Format

Content

摘要全文圖表視頻參考文獻施引文獻補充材料