急性胰腺炎患者血液中細胞因子的變化_《中國普外基礎與臨床雜志》

作者：

劉牧林 ¹ , 曹偉新 ² , 湯耀卿 ² , 尹浩然 ²

1. 蚌埠醫學院附屬醫院急診外科(蚌埠233000)2. 上海第二醫科大學瑞金醫院;

關鍵詞：

急性胰腺炎細胞因子

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為探討急性胰腺炎患者血液中細胞因子變化與病情嚴重度及多器官功能障礙(MOD)之間的關系，對1994年至1996年入院的36例急性胰腺炎患者依據RANSON評分和CT評分將其分為輕型組(12例)和重型胰腺炎組(24例)，又將重型胰腺炎組中發生MODS的9例定名為障礙組。在入院第0、4、8天測定血清TNF、IL-6、CRP值。結果顯示胰腺炎早期患者血液中細胞因子在輕型組、重型組和障礙組之間依次升高，并有顯著性差異(Ｐ＜0.05)。由此表明急性胰腺炎細胞因子升高與疾病嚴重度和并發癥發生有關，極度升高者可能發生多器官衰竭，動態檢測上述細胞因子有助于判斷患者的預后。

引用本文： 劉牧林,曹偉新,湯耀卿,尹浩然. 急性胰腺炎患者血液中細胞因子的變化. 中國普外基礎與臨床雜志, 1998, 5(6): 352-353下轉384. doi: 復制

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1. Beaux AC, Goldie AS, Ross JA, et al. Serum concentrations of inflammatory mediators related to organ failure in patients with acute pancreatitis. British J Surg, 1996; 83(4)∶349.
2. Heath DI, Cruickshank A, Gudgeon M, et al. Role of interleukin 6 in mediating the acute phase protein response and potential as and early means of severity assessment in acute pancreatitis. Gut, 1993; 34∶41.
3. Deitch EA. Multiple organ failure. Ann Surg, 1992; 216(2)∶117.
4. Mckay CJ, Gallagher G, Brooks B, et al. Increased monocyte cytokine production in association with systemic complication in acute pancreatitis. Br J Surg, 1996; 83(7)∶919.
5. Pezzilli R, Billi P, Miniero R, et al. Serum interleukin6, interleukin8, and β2microglobulin in early assessment of severity of acute pancreatitis comparison with serum creactive protein. Dig Dis Sci, 1995; 40(11)∶2341.
6. Rinderknecht H. Genetic determinants of mortality in acute necrotizing pancreatitis. Int J Pancreatol, 1994; 16(1)∶11.

《中國普外基礎與臨床雜志》

急性胰腺炎患者血液中細胞因子的變化

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《中國普外基礎與臨床雜志》

急性胰腺炎患者血液中細胞因子的變化

摘要 全文 圖表 視頻 參考文獻 施引文獻 補充材料

Format

Content

摘要全文圖表視頻參考文獻施引文獻補充材料