細胞凋亡和血管病變_《中國普外基礎與臨床雜志》

作者：

喬正榮綜述時德審校

重慶醫科大學附一院血管外科(重慶 400016);

關鍵詞：

細胞凋亡血管病變

視頻：

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摘要 全文 圖表 視頻 參考文獻 施引文獻 補充材料

目的探討細胞凋亡與血管病變的關系。
方法就細胞凋亡的概念、特征、基因調控、信號傳導及其與血管病變的關系作一綜述。
結果細胞因子、輻射、氧自由基等可誘導血管內皮細胞凋亡，導致血管損傷；而平滑肌細胞凋亡與動脈粥樣硬化和血管成形術后再狹窄密切相關。
結論細胞凋亡異常與血管病變密切相關。

引用本文： 喬正榮綜述時德審校. 細胞凋亡和血管病變. 中國普外基礎與臨床雜志, 2001, 8(3): 202-204. doi: 復制

1.	Kerr JF, Wyllie AH, Currie AR. Apoptosis: a basic biological phenomenon with wideranging implications in tissue kinetics 〔J〕. Br J Cancer, 1972； 26(2)∶239.
2.	Schwartzman PA, Cidlonski JA. The biochemistry and molecular biology of programmed cell death 〔J〕. Endocr Rev,1993； 14(3)∶133.
3.	Carson DA, Rireiro JM. Apoptosis and disease 〔J〕. Lancet, 1973； 341(10)∶1251.
4.	Dabrowska MI, Becks LL, Lelli JL, et al. Sulfur mustard induces apoptosis and necrosis in endothelial cells 〔J〕. Toxicol Appl Pharmacol,1996； 141(2)∶568.
5.	Davin MF, Wallers D, Song Q. Role of protein kinase activity in apoptosis 〔J〕. Experientia, 1996； 31(10)∶979.
6.	Boyle KM, Irwin JF, Humes BR, et al.Apoptosis in C3H10T1/2 cells:roles of intracellular PH, protein kinase C, and the Na+/H+ antiporter 〔J〕. J Cell Biochem,1997； 67(2)∶231.
7.	Pierre. Controlling cell death 〔J〕. Science, 1997； 275(21)∶1081.
8.	Reed JC. Bcl2 and the regulation of programmed cell death 〔J〕. J Cell Biol,1994； 124(8)∶1.
9.	Kane DJ, Sarafian YA, Anton R, et al.Bcl2 inhibition of neural death, decreasel generation of reactive oxygen species 〔J〕. Science, 1993； 262(4)∶1274.
10.	Tsukada J, Eguchi K, Migita K, et al.Transforming growth factor beta 1 induces apoptosic cell death with downregulated expression of bcl2 〔J〕. Biochem Biophys Res Commun, 1995； 210(3)∶1076.
11.	Roboye B, Mosselmans R, Eiers W, et al.Tumor necrosis factor induces apoptosis in normal endothelial cells in vitro 〔J〕. Am J Pathol,1991； 138(2)∶447.
12.	Slowik MK, Min W, Ardito T, et al.Evidence that tumor necrosis factor triggers apoptosis in human endothelial cells by interleukin1 converting enzymeline proteasedependent and independent pathways 〔J〕. Lab Invest,1997； 77(3)∶257.
13.	Langley RE, Bump EA, Quartuccio SG, et al.Radiation induced apoptosis in microvascular endothelial cells 〔J〕. Br J Cancer, 1997； 75(5)∶666.
14.	Haendeler J, Zeiher AM, Dimmeler S. Vitamin C and E prevent lipopolysaccharide induced apoptosis in human endothelial cells by modulation of bcl2 and bax 〔J〕. Eur J Pharmacol,1996； 317(3)∶407.
15.	Yang JJ, Kettritz R, Panel Falk RJ, et al. Apoptosis of endothelial cells induced by the neutrophil serine proteases proteinase 3 and elastase 〔J〕. Am J Pathol,1996； 149(5)∶1617.
16.	Baumgartner SM, Wagner L, Pettermann M, et al.High glucose triggened apoptosis in cultured endothelial cells 〔J〕. Diabetes, 1995； 44(11)∶1323.
17.	Kaiser D, Freyberg MA, Fried P. Lack of hemodynamic forces triggers apoptosis in vascular endothelial cells 〔J〕. Biochem Biophys Res Commun,1997； 231(3)∶586.
18.	Gobe G, Browning J, Howard T, et al.Apoptosis occurs in endothelial cells during hypertension induced microvascular rarefaction 〔J〕. J Struct Biol,1997； 118(1)∶63.
19.	Takey H, Tanaka Y, Suzuki K. Thrombosis and apoptosis 〔J〕. Rinsho Byori, 1997； 45(7)∶614.
20.	Dimmeler S, Haendeler J, Galle J, et al.Oxidized low density lipoprotein induces apoptosis of human endothelial cells by activation of CPP32 like proteases. A mechanistic clue to the response to injury hypothesis 〔J〕. Circulation, 1997； 95(7)∶1760.
21.	Geng YJ, Libby P. Evidence for apoptosis in advanced human atheroma. Colocalization with in terleukin1 betaconverting enzyme 〔J〕. Am J Pathol,1995； 147(2)∶251.
22.	Cho A, Courtman DW, Langille BL. Apoptosis in arteries of the neonatal lamb 〔J〕. Circ Res,1995； 76(7)∶168.
23.	Han DKM, Haudenschild CC, Hong MK, et al.Evidence for apoptosis in human atherogenesis and in a rat vascular injury model 〔J〕. Am J Pahtol,1995； 147(10)∶267.
24.	Bauriedel G, Schluckebier S, Welsch U, et al.Incidence and localization of apoptosis bodies in human arteriosclerosis lesions 〔J〕. Zkardiol,1996； 85(7)∶509.
25.	MurieLuce BP, Gabbiani F, Redard M, et al.Apoptosis participates in cellularity regulation during rat aortic intimal thickening 〔J〕. Am J Pathol,1995； 146(8)∶1059.
26.	Vaux DL, Haecker G, Strasser A. An evoluation perspective on apoptosis 〔J〕. Cell,1994； 76(7)∶1.
27.	Kockx MM, Cambier BA, Bortiex HE, et al.Roam cell replication and smooth muscle cell apoptosis in human saphenous vein grafts 〔J〕. Histopathology, 1994； 25(4)∶365.
28.	Geng YJ, Henderson LE, Levesque EB, et al.Fas is expressed in human atherosclerotic intima and promotes apoptosis of cytokine primed human vascular smooth cells 〔J〕. Arterioscler Thromb Vasc Biol,1997； 17(10)∶2200.
29.	Cai W, Devaux B, Schaper W, et al.The role of Fas/Apo 1 and apoptosis in the development of human atherosclerotic lesions 〔J〕. Atherosclerosis, 1997； 131(2)∶177.
30.	Bennett MR, Evan GI, Schwaiz SM. Apoptosis of rat vascular smooth cells is regulted by p53 dependent and independent pathways 〔J〕. Circ Res,1995； 77(4)∶266.

1. Kerr JF, Wyllie AH, Currie AR. Apoptosis: a basic biological phenomenon with wideranging implications in tissue kinetics 〔J〕. Br J Cancer, 1972； 26(2)∶239.
2. Schwartzman PA, Cidlonski JA. The biochemistry and molecular biology of programmed cell death 〔J〕. Endocr Rev,1993； 14(3)∶133.
3. Carson DA, Rireiro JM. Apoptosis and disease 〔J〕. Lancet, 1973； 341(10)∶1251.
4. Dabrowska MI, Becks LL, Lelli JL, et al. Sulfur mustard induces apoptosis and necrosis in endothelial cells 〔J〕. Toxicol Appl Pharmacol,1996； 141(2)∶568.
5. Davin MF, Wallers D, Song Q. Role of protein kinase activity in apoptosis 〔J〕. Experientia, 1996； 31(10)∶979.
6. Boyle KM, Irwin JF, Humes BR, et al.Apoptosis in C3H10T1/2 cells:roles of intracellular PH, protein kinase C, and the Na+/H+ antiporter 〔J〕. J Cell Biochem,1997； 67(2)∶231.
7. Pierre. Controlling cell death 〔J〕. Science, 1997； 275(21)∶1081.
8. Reed JC. Bcl2 and the regulation of programmed cell death 〔J〕. J Cell Biol,1994； 124(8)∶1.
9. Kane DJ, Sarafian YA, Anton R, et al.Bcl2 inhibition of neural death, decreasel generation of reactive oxygen species 〔J〕. Science, 1993； 262(4)∶1274.
10. Tsukada J, Eguchi K, Migita K, et al.Transforming growth factor beta 1 induces apoptosic cell death with downregulated expression of bcl2 〔J〕. Biochem Biophys Res Commun, 1995； 210(3)∶1076.
11. Roboye B, Mosselmans R, Eiers W, et al.Tumor necrosis factor induces apoptosis in normal endothelial cells in vitro 〔J〕. Am J Pathol,1991； 138(2)∶447.
12. Slowik MK, Min W, Ardito T, et al.Evidence that tumor necrosis factor triggers apoptosis in human endothelial cells by interleukin1 converting enzymeline proteasedependent and independent pathways 〔J〕. Lab Invest,1997； 77(3)∶257.
13. Langley RE, Bump EA, Quartuccio SG, et al.Radiation induced apoptosis in microvascular endothelial cells 〔J〕. Br J Cancer, 1997； 75(5)∶666.
14. Haendeler J, Zeiher AM, Dimmeler S. Vitamin C and E prevent lipopolysaccharide induced apoptosis in human endothelial cells by modulation of bcl2 and bax 〔J〕. Eur J Pharmacol,1996； 317(3)∶407.
15. Yang JJ, Kettritz R, Panel Falk RJ, et al. Apoptosis of endothelial cells induced by the neutrophil serine proteases proteinase 3 and elastase 〔J〕. Am J Pathol,1996； 149(5)∶1617.
16. Baumgartner SM, Wagner L, Pettermann M, et al.High glucose triggened apoptosis in cultured endothelial cells 〔J〕. Diabetes, 1995； 44(11)∶1323.
17. Kaiser D, Freyberg MA, Fried P. Lack of hemodynamic forces triggers apoptosis in vascular endothelial cells 〔J〕. Biochem Biophys Res Commun,1997； 231(3)∶586.
18. Gobe G, Browning J, Howard T, et al.Apoptosis occurs in endothelial cells during hypertension induced microvascular rarefaction 〔J〕. J Struct Biol,1997； 118(1)∶63.
19. Takey H, Tanaka Y, Suzuki K. Thrombosis and apoptosis 〔J〕. Rinsho Byori, 1997； 45(7)∶614.
20. Dimmeler S, Haendeler J, Galle J, et al.Oxidized low density lipoprotein induces apoptosis of human endothelial cells by activation of CPP32 like proteases. A mechanistic clue to the response to injury hypothesis 〔J〕. Circulation, 1997； 95(7)∶1760.
21. Geng YJ, Libby P. Evidence for apoptosis in advanced human atheroma. Colocalization with in terleukin1 betaconverting enzyme 〔J〕. Am J Pathol,1995； 147(2)∶251.
22. Cho A, Courtman DW, Langille BL. Apoptosis in arteries of the neonatal lamb 〔J〕. Circ Res,1995； 76(7)∶168.
23. Han DKM, Haudenschild CC, Hong MK, et al.Evidence for apoptosis in human atherogenesis and in a rat vascular injury model 〔J〕. Am J Pahtol,1995； 147(10)∶267.
24. Bauriedel G, Schluckebier S, Welsch U, et al.Incidence and localization of apoptosis bodies in human arteriosclerosis lesions 〔J〕. Zkardiol,1996； 85(7)∶509.
25. MurieLuce BP, Gabbiani F, Redard M, et al.Apoptosis participates in cellularity regulation during rat aortic intimal thickening 〔J〕. Am J Pathol,1995； 146(8)∶1059.
26. Vaux DL, Haecker G, Strasser A. An evoluation perspective on apoptosis 〔J〕. Cell,1994； 76(7)∶1.
27. Kockx MM, Cambier BA, Bortiex HE, et al.Roam cell replication and smooth muscle cell apoptosis in human saphenous vein grafts 〔J〕. Histopathology, 1994； 25(4)∶365.
28. Geng YJ, Henderson LE, Levesque EB, et al.Fas is expressed in human atherosclerotic intima and promotes apoptosis of cytokine primed human vascular smooth cells 〔J〕. Arterioscler Thromb Vasc Biol,1997； 17(10)∶2200.
29. Cai W, Devaux B, Schaper W, et al.The role of Fas/Apo 1 and apoptosis in the development of human atherosclerotic lesions 〔J〕. Atherosclerosis, 1997； 131(2)∶177.
30. Bennett MR, Evan GI, Schwaiz SM. Apoptosis of rat vascular smooth cells is regulted by p53 dependent and independent pathways 〔J〕. Circ Res,1995； 77(4)∶266.

《中國普外基礎與臨床雜志》

細胞凋亡和血管病變

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《中國普外基礎與臨床雜志》

細胞凋亡和血管病變

摘要 全文 圖表 視頻 參考文獻 施引文獻 補充材料

Format

Content

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