CT灌注成像的原理、技術及在腹部影像診斷中的應用_《中國普外基礎與臨床雜志》

作者：

宋彬

四川大學華西醫院放射科（成都610041）;

關鍵詞：

CT灌注成像腹部影像血流灌注

視頻：

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目的綜合評述CT灌注成像（CT perfusion imaging）的原理、技術要求及其在腹部影像診斷中的應用價值。
方法總結CT灌注成像的原理和技術要求，評價其在腹部疾病（主要是肝臟、胰腺）應用中所提供的組織器官微循環狀況、血流動力學變化及其它參數。
結果 CT灌注成像評價肝臟、胰腺病變，尤其是腫瘤性病變，除了能顯示解剖形態學改變，還能了解血供情況、血流動力學狀態等反映功能、代謝變化的信息，對腹部腫瘤性疾病的診斷有重要意義。
結論 CT灌注成像將在腹部疾病的影像診斷與鑒別診斷、腫瘤生物學行為和嚴重度評價、療效評估等方面發揮重要作用，具有較良好的臨床應用前景。

引用本文： 宋彬. CT灌注成像的原理、技術及在腹部影像診斷中的應用. 中國普外基礎與臨床雜志, 2004, 11(2): 171-174. doi: 復制

1.	Miles KA. Measurement of tissue perfusion by dynamic computed tomography [J]. Br J Radiol, 1991; 64(761)∶409.
2.	Miles KA, Hayball M, Dixon AK. Colour perfusion imaging: a new application of computed tomography [Ｊ]. Lancet, 1991; 337(8742)∶643.
3.	Miles KA, Hayball MP, Dixon AK. Functional images of hepatic perfusion obtained with dynamic CT [Ｊ]. Radiology, 1993; 188(2)∶405.
4.	Miles KA, Hayball MP, Dixon AK. Measurement of human pancreatic perfusion using dynamic computed tomography with perfusion imaging [Ｊ]. Br J Radiol, 1995; 68(809)∶471.
5.	Cenic A, Nabavi DG, Craen RA, et al. Dynamic CT measurement of cerebral blood flow: a validation study [Ｊ]. AJNR Am J Neuroradiol, 1999; 20(1)∶63.
6.	Axel L. Cerebral blood flow determination by rapidsequence computed tomography: theoretical analysis [Ｊ]. Radiology, 1980; 137(3)∶679.
7.	Eastwood JD, Lev MH, Azhari T, et al. CT perfusion scanning with deconvolution analysis: pilot study in patients with acute middle cerebral artery stroke [Ｊ]. Radiology, 2002; 222(1)∶227.
8.	Bell SD, Peters AM. Measurement of blood flow from firstpass radionuclide angiography: influence of bolus volume [Ｊ]. Eur J Nucl Med, 1991; 18(11)∶885.
9.	Klotz E, Konig M. Perfusion measurements of the brain: using dynamic CT for the quantitative assessment of cerebral ischemia in acute stroke [Ｊ]. Eur J Radiol, 1999; 30(3)∶170.
10.	Koenig M, Klotz E, Luka B, et al. Perfusion CT of the brain: diagnostic approach for early detection of ischemic stroke [Ｊ] Radiology, 1998; 209(1)∶85.
11.	Miles KA. Tumour angiogenesis and its relation to contrast enhancement on computed tomography: a review [Ｊ]. Eur J Radiol, 1999; 30(3)∶198.
12.	Dugdale PE, Miles KA, Bunce I, et al. CT measurement of perfusion and permeability within lymphoma masses and its ability to assess grade, activity, and chemotherapeutic response [Ｊ]. J Comput Assist Tomogr, 1999; 23(4)∶540.
13.	Brix G, Bahner ML, Hoffmann U, et al. Regional blood flow, capillary permeability, and compartmental volumes: measurement with dynamic CTinitial experience [Ｊ]. Radiology, 1999; 210(1)∶269.
14.	Miles KA, Leggett DA, Kelley BB, et al. In vivo assessment of neovascularization of liver metastases using perfusion CT [Ｊ]. Br J Radiol, 1998; 71(843)∶276.
15.	Bader TR, Herneth AM, Blaicher W, et al. Hepatic perfusion after liver transplantation: noninvasive measurement with dynamic singlesection CT [Ｊ]. Radiology, 1998; 209(1)∶129.
16.	Leggett DA, Kelley BB, Bunce IH, et al. Colorectal cancer: diagnostic potential of CT measurements of hepatic perfusion and implications for contrast enhancement protocols [Ｊ]. Radiology, 1997; 205(3)∶716.

1. Miles KA. Measurement of tissue perfusion by dynamic computed tomography [J]. Br J Radiol, 1991; 64(761)∶409.
2. Miles KA, Hayball M, Dixon AK. Colour perfusion imaging: a new application of computed tomography [Ｊ]. Lancet, 1991; 337(8742)∶643.
3. Miles KA, Hayball MP, Dixon AK. Functional images of hepatic perfusion obtained with dynamic CT [Ｊ]. Radiology, 1993; 188(2)∶405.
4. Miles KA, Hayball MP, Dixon AK. Measurement of human pancreatic perfusion using dynamic computed tomography with perfusion imaging [Ｊ]. Br J Radiol, 1995; 68(809)∶471.
5. Cenic A, Nabavi DG, Craen RA, et al. Dynamic CT measurement of cerebral blood flow: a validation study [Ｊ]. AJNR Am J Neuroradiol, 1999; 20(1)∶63.
6. Axel L. Cerebral blood flow determination by rapidsequence computed tomography: theoretical analysis [Ｊ]. Radiology, 1980; 137(3)∶679.
7. Eastwood JD, Lev MH, Azhari T, et al. CT perfusion scanning with deconvolution analysis: pilot study in patients with acute middle cerebral artery stroke [Ｊ]. Radiology, 2002; 222(1)∶227.
8. Bell SD, Peters AM. Measurement of blood flow from firstpass radionuclide angiography: influence of bolus volume [Ｊ]. Eur J Nucl Med, 1991; 18(11)∶885.
9. Klotz E, Konig M. Perfusion measurements of the brain: using dynamic CT for the quantitative assessment of cerebral ischemia in acute stroke [Ｊ]. Eur J Radiol, 1999; 30(3)∶170.
10. Koenig M, Klotz E, Luka B, et al. Perfusion CT of the brain: diagnostic approach for early detection of ischemic stroke [Ｊ] Radiology, 1998; 209(1)∶85.
11. Miles KA. Tumour angiogenesis and its relation to contrast enhancement on computed tomography: a review [Ｊ]. Eur J Radiol, 1999; 30(3)∶198.
12. Dugdale PE, Miles KA, Bunce I, et al. CT measurement of perfusion and permeability within lymphoma masses and its ability to assess grade, activity, and chemotherapeutic response [Ｊ]. J Comput Assist Tomogr, 1999; 23(4)∶540.
13. Brix G, Bahner ML, Hoffmann U, et al. Regional blood flow, capillary permeability, and compartmental volumes: measurement with dynamic CTinitial experience [Ｊ]. Radiology, 1999; 210(1)∶269.
14. Miles KA, Leggett DA, Kelley BB, et al. In vivo assessment of neovascularization of liver metastases using perfusion CT [Ｊ]. Br J Radiol, 1998; 71(843)∶276.
15. Bader TR, Herneth AM, Blaicher W, et al. Hepatic perfusion after liver transplantation: noninvasive measurement with dynamic singlesection CT [Ｊ]. Radiology, 1998; 209(1)∶129.
16. Leggett DA, Kelley BB, Bunce IH, et al. Colorectal cancer: diagnostic potential of CT measurements of hepatic perfusion and implications for contrast enhancement protocols [Ｊ]. Radiology, 1997; 205(3)∶716.

《中國普外基礎與臨床雜志》

CT灌注成像的原理、技術及在腹部影像診斷中的應用

摘要 全文 圖表 視頻 參考文獻 施引文獻 補充材料

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《中國普外基礎與臨床雜志》

CT灌注成像的原理、技術及在腹部影像診斷中的應用

摘要 全文 圖表 視頻 參考文獻 施引文獻 補充材料

Format

Content

摘要全文圖表視頻參考文獻施引文獻補充材料