Diagnosis and Treatment of Cystosarcoma Phyllodes and GiantFibroadenomas of Breast (Report of 〖STHZ〗17 Cases)_CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY

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施勇

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乳腺腫瘤葉狀囊肉瘤; 巨纖維腺瘤

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目的　探討乳腺葉狀囊肉瘤和巨纖維腺瘤的診斷和治療。
方法　回顧分析我院1985～2002年期間外科收治的9例乳腺葉狀囊肉瘤和8例乳腺巨纖維腺瘤的臨床資料。
結果　9例乳腺葉狀囊肉瘤中行單純乳房切除術4例，保留乳頭皮下乳房切除術1例，保留乳頭和部分壓縮腺體＋腫塊切除術1例，改良根治術3例; 術后恢復良好，僅1例復發。8例乳腺巨纖維腺瘤中行單純乳房切除術2例，保留乳頭皮下乳房切除術1例，保留乳頭和部分壓縮腺體＋腫塊切除術2例，單純乳腺腫塊切除術3例；術后恢復良好，術后2例復發。
結論　乳腺葉狀囊肉瘤和巨纖維腺瘤臨床上均表現為無痛性包塊，除乳腺葉狀囊肉瘤發病年齡較大、腫塊范圍大及易惡變外，二者主要依據病理檢查結果相鑒別；均以手術治療為主，根據患者年齡、腫塊大小以及病理檢查結果選擇不同的手術方式。

Citation： 施勇. Diagnosis and Treatment of Cystosarcoma Phyllodes and GiantFibroadenomas of Breast (Report of 〖STHZ〗17 Cases). CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY, 2007, 14(1): 92-93. doi: Copy

1.	Salvadori B, Cusumano F, Del Bo R, et al. Surgical treatment of phyllodes tumors of the breast [Ｊ]. Cancer， 1989; 63(12)∶2532.
2.	Dacic S, Kounelis S, Kouri E, et al. Immunohistochemical profile of cystosarcoma phyllodes of the breast: a study of 23 cases [Ｊ]. Breast J， 2002; 8(6)∶376.
3.	楊名添，劉廣森. 乳腺巨纖維腺瘤和葉狀囊肉瘤的臨床診斷與治療——52例分析 [Ｊ]. 中山醫科大學學報， 1987； 8(3)∶69.
4.	Chao TC, Lo YF, Chen SC, et al. Sonographic features of phyllodes tumors of the breast [Ｊ]. Ultrasound Obstet Gynecol， 2002; 20(1)∶64.
5.	Kapiris I, Nasiri N, A’Hern R, et al. Outcome and predictive factors of local recurrence and distant metastases following primary surgical treatment of high-grade malignant phyllodes tumours of the breast [Ｊ]. Eur J Surg Oncol， 2001; 27(8)∶723.
6.	Khan SA, Badve S. Phyllodes tumors of the breast [Ｊ]. Curr Treat Options Oncol， 2001; 2(2)∶139.
7.	Ridgway PF, Jacklin RK, Ziprin P, et al. Perioperative diagnosis of cystosarcoma phyllodes of the breast may be enhanced by MIB-1 index [Ｊ]. J Surg Res， 2004; 122(1)∶83.
8.	Kok KY, Telesinghe PU, Yapp SK. Treatment and outcome of cystosarcoma phyllodes in Brunei: a 13-year experience [Ｊ]. J R Coll Surg Edinb， 2001; 46(4)∶198.
9.	Zahner J, Bassler R. The rate of mitosis in cystosarcoma phyllodes (phyllodes tumor, WHO) of the breast. An analysis of 47 cases [Ｊ]. Arch Gynecol Obstet， 1989; 246(3)∶153.
10.	Pandey M, Mathew A, Kattoor J, et al. Malignant phyllodes tumor [Ｊ]. Breast J， 2001; 7(6)∶411.
11.	Daya M, Mahomva O, Madaree A, et al. Reduction mammoplasty in cases of giant fibroadenoma among adolescent females. Case reports and literature review [Ｊ]. S Afr J Surg， 2003; 41(2)∶39.

1. 　Salvadori B, Cusumano F, Del Bo R, et al. Surgical treatment of phyllodes tumors of the breast [Ｊ]. Cancer， 1989; 63(12)∶2532.
2. 　Dacic S, Kounelis S, Kouri E, et al. Immunohistochemical profile of cystosarcoma phyllodes of the breast: a study of 23 cases [Ｊ]. Breast J， 2002; 8(6)∶376.
3. 　楊名添，劉廣森. 乳腺巨纖維腺瘤和葉狀囊肉瘤的臨床診斷與治療——52例分析 [Ｊ]. 中山醫科大學學報， 1987； 8(3)∶69.
4. 　Chao TC, Lo YF, Chen SC, et al. Sonographic features of phyllodes tumors of the breast [Ｊ]. Ultrasound Obstet Gynecol， 2002; 20(1)∶64.
5. 　Kapiris I, Nasiri N, A’Hern R, et al. Outcome and predictive factors of local recurrence and distant metastases following primary surgical treatment of high-grade malignant phyllodes tumours of the breast [Ｊ]. Eur J Surg Oncol， 2001; 27(8)∶723.
6. 　Khan SA, Badve S. Phyllodes tumors of the breast [Ｊ]. Curr Treat Options Oncol， 2001; 2(2)∶139.
7. 　Ridgway PF, Jacklin RK, Ziprin P, et al. Perioperative diagnosis of cystosarcoma phyllodes of the breast may be enhanced by MIB-1 index [Ｊ]. J Surg Res， 2004; 122(1)∶83.
8. 　Kok KY, Telesinghe PU, Yapp SK. Treatment and outcome of cystosarcoma phyllodes in Brunei: a 13-year experience [Ｊ]. J R Coll Surg Edinb， 2001; 46(4)∶198.
9. 　Zahner J, Bassler R. The rate of mitosis in cystosarcoma phyllodes (phyllodes tumor, WHO) of the breast. An analysis of 47 cases [Ｊ]. Arch Gynecol Obstet， 1989; 246(3)∶153.
10. 　Pandey M, Mathew A, Kattoor J, et al. Malignant phyllodes tumor [Ｊ]. Breast J， 2001; 7(6)∶411.
11. 　Daya M, Mahomva O, Madaree A, et al. Reduction mammoplasty in cases of giant fibroadenoma among adolescent females. Case reports and literature review [Ｊ]. S Afr J Surg， 2003; 41(2)∶39.

CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY

Diagnosis and Treatment of Cystosarcoma Phyllodes and GiantFibroadenomas of Breast (Report of 〖STHZ〗17 Cases)

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