Report of 2 Cases of Gastrinoma and Literature Review_CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY

Authors：

王東 ¹ ,  彭蘭 ¹ , 黃小莉 ²

Corresponding?author：

彭蘭, Email: jacki33@163.com

Keywords：

胃泌素瘤; 診斷; 治療

Video：

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目的探討胃泌素瘤的診斷和治療經驗。
方法回顧綿陽市中心醫院確診的2例胃泌素瘤患者的臨床資料，并結合相關文獻分析。
結果 2例均表現為難治性消化性潰瘍，CT檢查發現胰腺包塊，生化與病理檢測確診為胃泌素瘤。
結論對多發性、異位、頑固性消化性潰瘍應警惕本病的存在，以免延誤診治.

Citation： 王東,彭蘭,黃小莉. Report of 2 Cases of Gastrinoma and Literature Review. CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY, 2010, 17(1): 81-82. doi: Copy

1.	Hung PD, Schubert ML, Mihas AA, et al. ZollingerEllison syndrome [Ｊ]. Curr Treat Options Gastroenterol, 2003; 6(2): 163170.
2.	朱預, 趙玉沛, 張太平, 等. 胃泌素瘤的診治經驗 [Ｊ]. 醫學臨床研究, 2005; 22(10): 13631365.
3.	Campana D, Piscitelli L, Mazzotta E, et al. ZollingerEllison syndrome: Diagnose and therapy [Ｊ]. Minerva Med, 2005; 96(3): 187206.
4.	石益海, 李景南, 錢家鳴. 胃泌素瘤的臨床特點分析和診斷方法比較 [Ｊ]. 胃腸病學, 2008; 13(4): 220222.
5.	Ramage JK, Davies AH, Ardill J, et al. Guidelines for the management of gastroenteropancreatic neuroendocrine (including carcinoid) tumours [Ｊ]. Gut, 2005; 54 Suppl 4: iv1iv16.
6.	Kouvaraki MA, Solorzano CC, Shapiro SE, et al. Surgical treatment of nonfunctioning pancreatic islet cell tumors [Ｊ]. J Surg Oncol, 2005; 89 (3): 170185.
7.	Nieto JM, Pisegna JR. The role of proton pump inhibitors in the treatment of ZollingerEllison syndrome [Ｊ]. Expert Opin Pharmacother, 2006; 7(2): 169175.
8.	Berna MJ, Hoffmann KM, Long SH, et al. Serum gastrin in ZollingerEllison syndrome:Ⅱ. Prospective study of gastrin provocative testing in 293 patients from the National Institutes of Health and comparison with 537 cases from the literature. evaluation of diagnostic criteria, proposal of new criteria, and correlations with clinical and tumoral features [Ｊ]. Medicine (Baltimore), 2006; 85 (6): 331364.

1. Hung PD, Schubert ML, Mihas AA, et al. ZollingerEllison syndrome [Ｊ]. Curr Treat Options Gastroenterol, 2003; 6(2): 163170.
2. 朱預, 趙玉沛, 張太平, 等. 胃泌素瘤的診治經驗 [Ｊ]. 醫學臨床研究, 2005; 22(10): 13631365.
3. Campana D, Piscitelli L, Mazzotta E, et al. ZollingerEllison syndrome: Diagnose and therapy [Ｊ]. Minerva Med, 2005; 96(3): 187206.
4. 石益海, 李景南, 錢家鳴. 胃泌素瘤的臨床特點分析和診斷方法比較 [Ｊ]. 胃腸病學, 2008; 13(4): 220222.
5. Ramage JK, Davies AH, Ardill J, et al. Guidelines for the management of gastroenteropancreatic neuroendocrine (including carcinoid) tumours [Ｊ]. Gut, 2005; 54 Suppl 4: iv1iv16.
6. Kouvaraki MA, Solorzano CC, Shapiro SE, et al. Surgical treatment of nonfunctioning pancreatic islet cell tumors [Ｊ]. J Surg Oncol, 2005; 89 (3): 170185.
7. Nieto JM, Pisegna JR. The role of proton pump inhibitors in the treatment of ZollingerEllison syndrome [Ｊ]. Expert Opin Pharmacother, 2006; 7(2): 169175.
8. Berna MJ, Hoffmann KM, Long SH, et al. Serum gastrin in ZollingerEllison syndrome:Ⅱ. Prospective study of gastrin provocative testing in 293 patients from the National Institutes of Health and comparison with 537 cases from the literature. evaluation of diagnostic criteria, proposal of new criteria, and correlations with clinical and tumoral features [Ｊ]. Medicine (Baltimore), 2006; 85 (6): 331364.

CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY

Report of 2 Cases of Gastrinoma and Literature Review

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