【摘要】　目的　 探討左炔諾孕酮宮內釋放系統聯合桂枝茯苓膠囊治療子宮腺肌病的療效。　方法　 2006年2月-2010年2月108例子宮腺肌病患者隨機分為觀察組（n=56）與對照組（n=52），觀察組患者宮內放置左炔諾孕酮宮內釋放系統，同時口服中成藥桂枝茯苓膠囊，3粒/次，3次/d，連服6個月。對照組單放置左炔諾孕酮宮內釋放系統進行治療，觀察月經量、痛經程度、子宮體積及血清CA125水平變化。　結果　 6個月后，觀察組患者痛經明顯緩解，月經量顯著減少，子宮體積縮小，血清CA125水平明顯降低，治療前后比較，差異均有統計學意義（P lt;0.05）；與對照組比較，痛經評級、子宮體積縮小、血清CA125水平差異均有統計學意義（P lt;0.05）。　結論　 左炔諾孕酮宮內釋放系統與桂枝茯苓膠囊聯合治療子宮腺肌病安全有效，滿意度高，值得臨床推廣應用。
【Abstract】　Objective　 To evaluate the therapeutic effect of levonorgestrel-releasing intrauterine system (LNG-IUS) combined with Guizhi Fulin capsules treating adenomyosis.　Methods　 A total of 108 patients with adenomyosis diagnosed in our hospital from February 2006 to February 2010 were randomly divided into the observation group (n=56) and the control group (n=52). The patients in the observation group were treated with LNG-IUS and simultaneously administrated orally with the Guizhi Fulin capsules (three capsules per time, three times per day for six continuous months). The patients in the control group were treated with LNG -IUS only. The changes of the menstrual blood volume, severity of dysmenorrhea, uterine volume and the level of serum CA125 were observed and evaluated.　Results　 After six months’ treatment, dysmenorrhea of all the patients was obviously alleviated, the menstrual blood volume reduced significantly, the uterine volume shrank, and the level of serum CA125 decreased significantly; the results after the treatment differed much from that before the treatment (P lt;0.05). Compared with those in the control group, the differences in the grades of the dysmenorrheal, shrinkage of the uterine volume and the level of serum CA125 were statistically significant (P lt;0.05).　Conclusion　 Combined usage of LNG-IUS and Guizhi Fulin capsules is an effective and safe way treating adenomyosis.

引用本文： 梁榮麗,羅宋. 左炔諾孕酮宮內釋放系統聯合桂枝茯苓膠囊治療子宮腺肌病的療效觀察. 華西醫學, 2011, 26(1): 72-74. doi: 復制