Annual report (2025) of publications in <i>Epilepsia</i>, the official journal of the International League Against Epilepsy_Journal of Epilepsy

Authors：

HU Xiaowei ¹ , WANG Pinchun ¹ , MA Jingyou ¹ , LU Yeting ¹ , PAN Shengjie ¹ , XU Min ¹ , CHENG Qingzhang ² , TANG Jihong ³ , SHAO Guofu ⁴ , LIU Jiannong ⁵ ,  LI Yan ³

1. Department of Neurology, The First Affiliated Hospital of Soochow University, Suzhou 215006, China;
2. Department of Neurology, Suzhou Hospital, Nanjing Medical University, Suzhou 215006, China;
3. Department of Neurology, Children's Hospital of Soochow University, Suzhou 215006, China;
4. Department of Neurology, The Second Affiliated Hospital of Soochow University, Suzhou 215006, China;
5. Department of Neurology, Suzhou Guangji Hospital, Suzhou 215006, China;

Corresponding?author：

LI Yan, Email: yan62bh@126.com

Keywords：

Epilepsia; Journal; Annual report; Review

DOI：

10.7507/2096-0247.202603016

Video：

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This article reviewed the literature published in Epilepsia in 2025. A total of 449 articles were published in 2025, representing a 29.0% increase compared to 2024 (348 articles). All the publications included 3 editorials, 38 critical reviews (systematic reviews and meta-analyses), 12 commentaries, 319 original research articles, 39 brief reports, 28 others (announcements, correspondence, and errata), and 10 special reports. The increase in publications in 2025 compared to 2024 was primarily driven by clinical studies (314 vs. 221, a 42.1% growth). Independently published articles by Chinese authors also saw a substantial rise, totaling 29 papers, which marked a 190% increase over 2024. This annual report focused on epilepsy and artificial intelligence, annual special reports and researches by chinese authors, highlighting innovations and developments in both clinical and basic epilepsy research domestically and internationally. It aimed to provide valuable insights for specialists to refine diagnostic and therapeutic techniques and broaden their academic horizons.

1.	胡小偉, 徐敏, 程慶璋, 等. 國際抗癲癇聯盟期刊Epilepsia文獻2024年度報告. 癲癇雜志, 2025, 11(4): 340-345.
2.	Alcala-Zermeno JL, Gregg NM, Osman G, et al. Optimizing stimulation parameters for anterior thalamic nuclei deep brain stimulation in epilepsy: a randomized crossover trial. Epilepsia, 2025, 66(9): 3309-3317.
3.	Anand V, Gulati S, Agarwala A, et al. Comparison of efficacy of low glycemic index treatment and modified Atkins diet among children with drug-resistant epilepsy: A randomized non-inferiority trial. Epilepsia, 2025, 66(5): 1550-1559.
4.	Pattnaik SS, Sarangi SC, Dash Y, et al. Role of vitamin D supplementation and vitamin D receptor in drug-resistant epilepsy: a double-blind placebo-controlled trial conducted in India. Epilepsia, 2025, 66(10): 3716-3729.
5.	Vossler DG, Porter BE, Kira R, et al. Efficacy and safety of perampanel in patients with seizures associated with Lennox-Gastaut syndrome: a randomized trial. Epilepsia, 2025, 66(2): 379-393.
6.	Wang YY, Ma L, Shi XJ, et al. Cerebellar transcranial magnetic stimulation to treat drug-resistant epilepsy: a randomized, controlled, crossover clinical trial. Epilepsia, 2025, 66(1): 240-252.
7.	Alkofer M, Yang C, Ganglberger W, et al. Automated detection of interictal epileptiform discharges with few electroencephalographic channels. Epilepsia, 2025, 66(7): e114-e120.
8.	Tjepkema-Cloostermans MC, Tannemaat MR, Wieske L, et al. Expert level of detection of interictal discharges with a deep neural network. Epilepsia, 2025, 66(1): 184-194.
9.	Sundrani S, Johnson GW, Doss DJ, et al. Deep learning on brief interictal intracranial recordings can accurately characterize seizure onset zones. Epilepsia, 2025, 66(9): 3180-3192.
10.	Boyne A, Yeh HJ, Allam AK, et al. Video-based detection of tonic–clonic seizures using a three-dimensional convolutional neural network. Epilepsia, 2025, 66(7): 2495-2506.
11.	Macea J, Chatzichristos C, Bhagubai M, et al. Tailoring antiseizure treatment with a wearable device: a proof-of-concept study in absence epilepsy. Epilepsia, 2025, 66(7): 2295-2306.
12.	Newton TJ, Frankel MA, Tosi Z, et al. Validation of a discrete electrographic seizure detection algorithm for extended-duration, reduced-channel wearable EEG. Epilepsia, 2025, 66(7): 2433-2443.
13.	Alva-Diaz C, Nieto-Gutierrez W, Rodriguez-López E, et al. Smartphone-based interventions for the diagnosis of epileptic seizures: a systematic review and meta-analysis. Epilepsia, 2025, 66(9): 3138-3152.
14.	Vieluf S, Tomioka S, Zhang B, et al. Seizure monitoring by combined diary and wearable data: a multicenter, longitudinal, observational study. Epilepsia, 2025, 66(11): 4259-4271.
15.	Fang S, Holgate B, Shek A, et al. Extracting epilepsy-related information from unstructured clinic letters using large language models. Epilepsia, 2025, 66(9): 3369-3384.
16.	Ford J, Pevy N, Grunewald R, et al. Can artificial intelligence diagnose seizures based on patients' descriptions? A study of GPT-4. Epilepsia, 2025, 66(6): 1959-1974.
17.	Amacher SA, Baumann SM, Berger S, et al. Can the large language model ChatGPT-4omni predict outcomes in adult patients with status epilepticus? Epilepsia, 2025, 66(3): 674-685.
18.	McLaren JR, Yuan D, Beniczky S, et al. The future of EEG education in the era of artificial intelligence. Epilepsia, 2025, 66(6): 1838-1842.
19.	de Curtis M, Asukile M, Battaglia G, et al. Basic and preclinical epilepsy research Scientists' perception of clinical epileptology. Epilepsia, 2025, 66(1): 60-74.
20.	Nico Enslin JM, Muh CR, Wang X, et al. Epilepsy surgery education and practice around the globe: An ILAE taskforce report. Epilepsia, 2025, 66(2): 319-327.
21.	Gandy M, Wu W, Woldhuis T, et al. Integrated care for mental health in epilepsy: a systematic review and meta-synthesis by the International League Against Epilepsy Integrated Mental Health Care Pathways Task Force. Epilepsia, 2025, 66(4): 1024-1040.
22.	Lin K, Eyal S, Demarchi IG, et al. Prioritizing questions and topics for the development of guidelines and consensus-based recommendations supported by ILAE: a scoping review and proposal of prioritization criteria. Epilepsia, 2025, 66(5): 1406-1416.
23.	Beniczky S, Trinka E, Wirrell E, et al. Updated classification of epileptic seizures: Position paper of the International League Against Epilepsy. Epilepsia, 2025, 66(6): 1804-1823.
24.	Hingray C, Popkirov S, Kozlowska K, et al. Functional/dissociative seizures: proposal for a new diagnostic label and definition by the ILAE task force. Epilepsia, 2025, 66(11): 4162-4182.
25.	Vinayan KP, Asadi-Pooya AA, Jyotsna AS, et al. Availability and affordability of cannabinoids for epilepsy treatment across different geographic settings—a survey from the ILAE Plant-Based Therapy Task Force. Epilepsia, 2025, 66(12): 4639-4653.
26.	Perucca P, Battino D, Bromley R, et al. Epilepsy-pregnancy registries: an update. Epilepsia, 2025, 66(1): 47-59.
27.	Casillas-Espinosa PM, Wong JC, Grabon W, et al. WONOEP appraisal: Targeted therapy development for early onset epilepsies. Epilepsia, 2025, 66(2): 328-340.
28.	Scheffer IE, French J, Valente KD, et al. Operational definition of developmental and epileptic encephalopathies to underpin the design of therapeutic trials. Epilepsia, 2025, 66(4): 1014-1023.
29.	Cendes F, Auvin S. An interview with Louison Pineau 2025 Epilepsia prize winner for basic science. Epilepsia, 2025, 66(7): 2594-2595.
30.	Pineau L, Buhler E, Tarhini S, et al. Pathogenic MTOR somatic variant causing focal cortical dysplasia drives hyperexcitability via overactivation of neuronal GluN2C N-methyl-D-aspartate receptors. Epilepsia, 2024, 65(7): 2111-2126.
31.	Cendes F, Auvin S. An interview with Tobias Bauer, 2025 Epilepsia Prize winner for clinical research. Epilepsia, 2025, 66(7): 2592-2593.
32.	Bauer T, Olbrich S, Groteklaes A, et al. Proof of concept: portable ultra-low-field magnetic resonance imaging for the diagnosis of epileptogenic brain pathologies. Epilepsia, 2024, 65(12): 3607-3618.
33.	Hu Y, Chen S, Mao F, et al. Which is the most cost-effective antiseizure medication for initial monotherapy for focal epilepsy? Epilepsia, 2025, 66(4): 1129-1142.
34.	Yang B, Luo W, Zhao B, et al. Anatomical categorization of insulo-opercular focal cortical dysplasia and the spatial patterns of stereoelectroencephalography. Epilepsia, 2025, 66(3): 847-858.
35.	Lin Q, Cao D, Li W, et al. Connectome architecture for gray matter atrophy and surgical outcomes in temporal lobe epilepsy. Epilepsia, 2025, 66(6): 2053-2065.
36.	Liu Q, Zhu R, Wang Y, et al. Surgical outcomes and motor function in pediatric peri-Rolandic epilepsy: a single center's experience with 152 cases. Epilepsia, 2025, 66(7): 2190-2197.
37.	Li Z, Ren J, Zhao B, et al. Concordant interictal stereoelectroencephalographic high-frequency oscillations and magnetoencephalography predict better surgical outcomes in focal epilepsy. Epilepsia, 2025, 66(10): 3880-3894.
38.	Wang S, He C, Chen X, et al. Resection of the temporal piriform cortex in mesial temporal lobe epilepsy: association with seizure freedom in a retrospective cohort study. Epilepsia, 2025, 66(11): 4211-4222.
39.	Yao Y, Wang X, Zhao B, et al. Mapping electrophysiological connectivity of pulvinar in seizure propagation and neuromodulation. Epilepsia, 2025, 66(11): 4308-4323.
40.	Li H, Shao X, He F, et al. Neural dynamics remodeling induced by ketogenic diet therapy in drug-resistant epilepsy: a functional magnetic resonance imaging study. Epilepsia, 2025, 66(9): 3465-3479.
41.	Li N, Zhang H, Yang C, et al. Real-world comparison of first-line antiseizure monotherapy and the role of age at treatment initiation in newly diagnosed childhood epilepsy: a cohort study from a tertiary center. Epilepsia, 2025, 66(12): 4738-4751.
42.	Hao N, Abdulaziz AT, Lu L, et al. Seizure control and pregnancy outcomes in Chinese women with epilepsy: a prospective multicenter cohort study. Epilepsia, 2025, 66(5): 1573-1584.
43.	Yu Y, Tuo M, Chen Z, et al. Association between severity of stroke and poststroke epilepsy among patients with ischemic stroke: mediating role of infection and early seizure. Epilepsia, 2025, 66(6): 2011-2021.
44.	Sun Y, Guan M, Chen X, et al. Deep learning-based classification and segmentation of interictal epileptiform discharges using multichannel electroencephalography. Epilepsia, 2025, 66(9): 3398-3410.
45.	Hao S, Zhao H, Feng Z, et al. HD-EEG source imaging with simultaneous SEEG recording in drug-resistant epilepsy. Epilepsia, 2025, 66(11): 4451-4464.
46.	Qiao Z, Yang Y, Chen Y, et al. Emerging translocator protein–positron emission tomographic imaging improves detection of focal cortical dysplasia. Epilepsia, 2025, 66(7): 2339-2352.
47.	Huang Y, Xu S, Wang X, et al. Neurologic impairment and brain microstructural–functional alterations in infantile spasms: A multimodal magnetic resonance imaging study. Epilepsia, 2025, 66(12): 4950-4959.
48.	Zhang S, Liu Y, Ma L, et al. Quantitative susceptibility mapping of iron deposition in sporadic cerebral cavernous malformation–related epilepsy. Epilepsia, 2025, 66(4): 1304-1314.
49.	Yang B, Yao C, Xu J, et al. Common network related to hyperkinetic seizures revealed by functional lesion network mapping. Epilepsia, 2025, 66(12): 4881-4894.
50.	Guo X, Wang C, Long D, et al. Clinical phenotypic spectrum of NRXN1 microdeletions and their association with epilepsy: a systematic review and meta-analysis. Epilepsia, 2025, 66(6): 2022-2035.
51.	Liu C-Q, Sun M-Z, Lin Y-M, et al. Protective effect of CACNA1A deficiency in oligogenic refractory epilepsy with CACNA1A-CELSR2 digenic mutations. Epilepsia, 2025, 66(7): 2391-2406.
52.	Li X, Wang L, Liang X-Y, et al. Variants in CSMD2 and CSMD3, genes involved in synaptogenesis, are associated with epilepsies. Epilepsia, 2025, 66(11): 4394-4410.
53.	Wang X, Zhu J, Li X, et al. Association study of ADORA2A gene polymorphisms with adverse drug reactions to valproic acid and oxcarbazepine in the treatment of children with epilepsy. Epilepsia, 2025, 66(12): 4725-4737.
54.	Zhang Q, Yamanaka H, Li P, et al. Haploinsufficiency of brain-specific kinase BRSK1 causes epilepsy and neurodevelopmental disorders. Epilepsia, 2025, 66(12): 5033-5054.
55.	Shen S, Sun H, Dong Z, et al. Prevalence, clinical characteristics, and risk factors for psychosis in people with epilepsy: a multicenter retrospective cohort study. Epilepsia, 2025, 66(8): 2904-2915.
56.	Lu Y, Ge Y, Wang R, et al. Familial adult myoclonus epilepsy: A comprehensive diagnostic strategy for clinical practice. Epilepsia, 2025, 66(11): 4107-4121.
57.	Jia X, Xu J, Zhang Y, et al. Elevated Astrocytic NFAT5 of the hippocampus increases epilepsy susceptibility in hypoxic-ischemic mice. Epilepsia, 2025, 66(3): 817-832.
58.	Tao Y, Zhao Y, Zhong W, et al. Asymmetric dynamics of GABAergic system and paradoxical responses of GABAergic neurons in piriform seizures. Epilepsia, 2025, 66(2): 583-598.
59.	Liang H, Qin L, Feng R, et al. Increased NaV1. 2 expression and its interaction with CaM contribute to the hyperexcitability induced by prolonged inhibition of CaMKII. Epilepsia, 2025, 66(7): 2521-2537.
60.	Jiang D, Yang L, Yu L, et al. One-hertz low-frequency stimulation of anterior substantia nigra pars reticulata attenuates seizure via biased disinhibitory circuits. Epilepsia, 2025, 66(5): 1703-1717.

1. 胡小偉, 徐敏, 程慶璋, 等. 國際抗癲癇聯盟期刊Epilepsia文獻2024年度報告. 癲癇雜志, 2025, 11(4): 340-345.
2. Alcala-Zermeno JL, Gregg NM, Osman G, et al. Optimizing stimulation parameters for anterior thalamic nuclei deep brain stimulation in epilepsy: a randomized crossover trial. Epilepsia, 2025, 66(9): 3309-3317.
3. Anand V, Gulati S, Agarwala A, et al. Comparison of efficacy of low glycemic index treatment and modified Atkins diet among children with drug-resistant epilepsy: A randomized non-inferiority trial. Epilepsia, 2025, 66(5): 1550-1559.
4. Pattnaik SS, Sarangi SC, Dash Y, et al. Role of vitamin D supplementation and vitamin D receptor in drug-resistant epilepsy: a double-blind placebo-controlled trial conducted in India. Epilepsia, 2025, 66(10): 3716-3729.
5. Vossler DG, Porter BE, Kira R, et al. Efficacy and safety of perampanel in patients with seizures associated with Lennox-Gastaut syndrome: a randomized trial. Epilepsia, 2025, 66(2): 379-393.
6. Wang YY, Ma L, Shi XJ, et al. Cerebellar transcranial magnetic stimulation to treat drug-resistant epilepsy: a randomized, controlled, crossover clinical trial. Epilepsia, 2025, 66(1): 240-252.
7. Alkofer M, Yang C, Ganglberger W, et al. Automated detection of interictal epileptiform discharges with few electroencephalographic channels. Epilepsia, 2025, 66(7): e114-e120.
8. Tjepkema-Cloostermans MC, Tannemaat MR, Wieske L, et al. Expert level of detection of interictal discharges with a deep neural network. Epilepsia, 2025, 66(1): 184-194.
9. Sundrani S, Johnson GW, Doss DJ, et al. Deep learning on brief interictal intracranial recordings can accurately characterize seizure onset zones. Epilepsia, 2025, 66(9): 3180-3192.
10. Boyne A, Yeh HJ, Allam AK, et al. Video-based detection of tonic–clonic seizures using a three-dimensional convolutional neural network. Epilepsia, 2025, 66(7): 2495-2506.
11. Macea J, Chatzichristos C, Bhagubai M, et al. Tailoring antiseizure treatment with a wearable device: a proof-of-concept study in absence epilepsy. Epilepsia, 2025, 66(7): 2295-2306.
12. Newton TJ, Frankel MA, Tosi Z, et al. Validation of a discrete electrographic seizure detection algorithm for extended-duration, reduced-channel wearable EEG. Epilepsia, 2025, 66(7): 2433-2443.
13. Alva-Diaz C, Nieto-Gutierrez W, Rodriguez-López E, et al. Smartphone-based interventions for the diagnosis of epileptic seizures: a systematic review and meta-analysis. Epilepsia, 2025, 66(9): 3138-3152.
14. Vieluf S, Tomioka S, Zhang B, et al. Seizure monitoring by combined diary and wearable data: a multicenter, longitudinal, observational study. Epilepsia, 2025, 66(11): 4259-4271.
15. Fang S, Holgate B, Shek A, et al. Extracting epilepsy-related information from unstructured clinic letters using large language models. Epilepsia, 2025, 66(9): 3369-3384.
16. Ford J, Pevy N, Grunewald R, et al. Can artificial intelligence diagnose seizures based on patients' descriptions? A study of GPT-4. Epilepsia, 2025, 66(6): 1959-1974.
17. Amacher SA, Baumann SM, Berger S, et al. Can the large language model ChatGPT-4omni predict outcomes in adult patients with status epilepticus? Epilepsia, 2025, 66(3): 674-685.
18. McLaren JR, Yuan D, Beniczky S, et al. The future of EEG education in the era of artificial intelligence. Epilepsia, 2025, 66(6): 1838-1842.
19. de Curtis M, Asukile M, Battaglia G, et al. Basic and preclinical epilepsy research Scientists' perception of clinical epileptology. Epilepsia, 2025, 66(1): 60-74.
20. Nico Enslin JM, Muh CR, Wang X, et al. Epilepsy surgery education and practice around the globe: An ILAE taskforce report. Epilepsia, 2025, 66(2): 319-327.
21. Gandy M, Wu W, Woldhuis T, et al. Integrated care for mental health in epilepsy: a systematic review and meta-synthesis by the International League Against Epilepsy Integrated Mental Health Care Pathways Task Force. Epilepsia, 2025, 66(4): 1024-1040.
22. Lin K, Eyal S, Demarchi IG, et al. Prioritizing questions and topics for the development of guidelines and consensus-based recommendations supported by ILAE: a scoping review and proposal of prioritization criteria. Epilepsia, 2025, 66(5): 1406-1416.
23. Beniczky S, Trinka E, Wirrell E, et al. Updated classification of epileptic seizures: Position paper of the International League Against Epilepsy. Epilepsia, 2025, 66(6): 1804-1823.
24. Hingray C, Popkirov S, Kozlowska K, et al. Functional/dissociative seizures: proposal for a new diagnostic label and definition by the ILAE task force. Epilepsia, 2025, 66(11): 4162-4182.
25. Vinayan KP, Asadi-Pooya AA, Jyotsna AS, et al. Availability and affordability of cannabinoids for epilepsy treatment across different geographic settings—a survey from the ILAE Plant-Based Therapy Task Force. Epilepsia, 2025, 66(12): 4639-4653.
26. Perucca P, Battino D, Bromley R, et al. Epilepsy-pregnancy registries: an update. Epilepsia, 2025, 66(1): 47-59.
27. Casillas-Espinosa PM, Wong JC, Grabon W, et al. WONOEP appraisal: Targeted therapy development for early onset epilepsies. Epilepsia, 2025, 66(2): 328-340.
28. Scheffer IE, French J, Valente KD, et al. Operational definition of developmental and epileptic encephalopathies to underpin the design of therapeutic trials. Epilepsia, 2025, 66(4): 1014-1023.
29. Cendes F, Auvin S. An interview with Louison Pineau 2025 Epilepsia prize winner for basic science. Epilepsia, 2025, 66(7): 2594-2595.
30. Pineau L, Buhler E, Tarhini S, et al. Pathogenic MTOR somatic variant causing focal cortical dysplasia drives hyperexcitability via overactivation of neuronal GluN2C N-methyl-D-aspartate receptors. Epilepsia, 2024, 65(7): 2111-2126.
31. Cendes F, Auvin S. An interview with Tobias Bauer, 2025 Epilepsia Prize winner for clinical research. Epilepsia, 2025, 66(7): 2592-2593.
32. Bauer T, Olbrich S, Groteklaes A, et al. Proof of concept: portable ultra-low-field magnetic resonance imaging for the diagnosis of epileptogenic brain pathologies. Epilepsia, 2024, 65(12): 3607-3618.
33. Hu Y, Chen S, Mao F, et al. Which is the most cost-effective antiseizure medication for initial monotherapy for focal epilepsy? Epilepsia, 2025, 66(4): 1129-1142.
34. Yang B, Luo W, Zhao B, et al. Anatomical categorization of insulo-opercular focal cortical dysplasia and the spatial patterns of stereoelectroencephalography. Epilepsia, 2025, 66(3): 847-858.
35. Lin Q, Cao D, Li W, et al. Connectome architecture for gray matter atrophy and surgical outcomes in temporal lobe epilepsy. Epilepsia, 2025, 66(6): 2053-2065.
36. Liu Q, Zhu R, Wang Y, et al. Surgical outcomes and motor function in pediatric peri-Rolandic epilepsy: a single center's experience with 152 cases. Epilepsia, 2025, 66(7): 2190-2197.
37. Li Z, Ren J, Zhao B, et al. Concordant interictal stereoelectroencephalographic high-frequency oscillations and magnetoencephalography predict better surgical outcomes in focal epilepsy. Epilepsia, 2025, 66(10): 3880-3894.
38. Wang S, He C, Chen X, et al. Resection of the temporal piriform cortex in mesial temporal lobe epilepsy: association with seizure freedom in a retrospective cohort study. Epilepsia, 2025, 66(11): 4211-4222.
39. Yao Y, Wang X, Zhao B, et al. Mapping electrophysiological connectivity of pulvinar in seizure propagation and neuromodulation. Epilepsia, 2025, 66(11): 4308-4323.
40. Li H, Shao X, He F, et al. Neural dynamics remodeling induced by ketogenic diet therapy in drug-resistant epilepsy: a functional magnetic resonance imaging study. Epilepsia, 2025, 66(9): 3465-3479.
41. Li N, Zhang H, Yang C, et al. Real-world comparison of first-line antiseizure monotherapy and the role of age at treatment initiation in newly diagnosed childhood epilepsy: a cohort study from a tertiary center. Epilepsia, 2025, 66(12): 4738-4751.
42. Hao N, Abdulaziz AT, Lu L, et al. Seizure control and pregnancy outcomes in Chinese women with epilepsy: a prospective multicenter cohort study. Epilepsia, 2025, 66(5): 1573-1584.
43. Yu Y, Tuo M, Chen Z, et al. Association between severity of stroke and poststroke epilepsy among patients with ischemic stroke: mediating role of infection and early seizure. Epilepsia, 2025, 66(6): 2011-2021.
44. Sun Y, Guan M, Chen X, et al. Deep learning-based classification and segmentation of interictal epileptiform discharges using multichannel electroencephalography. Epilepsia, 2025, 66(9): 3398-3410.
45. Hao S, Zhao H, Feng Z, et al. HD-EEG source imaging with simultaneous SEEG recording in drug-resistant epilepsy. Epilepsia, 2025, 66(11): 4451-4464.
46. Qiao Z, Yang Y, Chen Y, et al. Emerging translocator protein–positron emission tomographic imaging improves detection of focal cortical dysplasia. Epilepsia, 2025, 66(7): 2339-2352.
47. Huang Y, Xu S, Wang X, et al. Neurologic impairment and brain microstructural–functional alterations in infantile spasms: A multimodal magnetic resonance imaging study. Epilepsia, 2025, 66(12): 4950-4959.
48. Zhang S, Liu Y, Ma L, et al. Quantitative susceptibility mapping of iron deposition in sporadic cerebral cavernous malformation–related epilepsy. Epilepsia, 2025, 66(4): 1304-1314.
49. Yang B, Yao C, Xu J, et al. Common network related to hyperkinetic seizures revealed by functional lesion network mapping. Epilepsia, 2025, 66(12): 4881-4894.
50. Guo X, Wang C, Long D, et al. Clinical phenotypic spectrum of NRXN1 microdeletions and their association with epilepsy: a systematic review and meta-analysis. Epilepsia, 2025, 66(6): 2022-2035.
51. Liu C-Q, Sun M-Z, Lin Y-M, et al. Protective effect of CACNA1A deficiency in oligogenic refractory epilepsy with CACNA1A-CELSR2 digenic mutations. Epilepsia, 2025, 66(7): 2391-2406.
52. Li X, Wang L, Liang X-Y, et al. Variants in CSMD2 and CSMD3, genes involved in synaptogenesis, are associated with epilepsies. Epilepsia, 2025, 66(11): 4394-4410.
53. Wang X, Zhu J, Li X, et al. Association study of ADORA2A gene polymorphisms with adverse drug reactions to valproic acid and oxcarbazepine in the treatment of children with epilepsy. Epilepsia, 2025, 66(12): 4725-4737.
54. Zhang Q, Yamanaka H, Li P, et al. Haploinsufficiency of brain-specific kinase BRSK1 causes epilepsy and neurodevelopmental disorders. Epilepsia, 2025, 66(12): 5033-5054.
55. Shen S, Sun H, Dong Z, et al. Prevalence, clinical characteristics, and risk factors for psychosis in people with epilepsy: a multicenter retrospective cohort study. Epilepsia, 2025, 66(8): 2904-2915.
56. Lu Y, Ge Y, Wang R, et al. Familial adult myoclonus epilepsy: A comprehensive diagnostic strategy for clinical practice. Epilepsia, 2025, 66(11): 4107-4121.
57. Jia X, Xu J, Zhang Y, et al. Elevated Astrocytic NFAT5 of the hippocampus increases epilepsy susceptibility in hypoxic-ischemic mice. Epilepsia, 2025, 66(3): 817-832.
58. Tao Y, Zhao Y, Zhong W, et al. Asymmetric dynamics of GABAergic system and paradoxical responses of GABAergic neurons in piriform seizures. Epilepsia, 2025, 66(2): 583-598.
59. Liang H, Qin L, Feng R, et al. Increased NaV1. 2 expression and its interaction with CaM contribute to the hyperexcitability induced by prolonged inhibition of CaMKII. Epilepsia, 2025, 66(7): 2521-2537.
60. Jiang D, Yang L, Yu L, et al. One-hertz low-frequency stimulation of anterior substantia nigra pars reticulata attenuates seizure via biased disinhibitory circuits. Epilepsia, 2025, 66(5): 1703-1717.

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Latest ArticlesAnnual report (2025) of publications in Epilepsia, the official journal of the International League Against Epilepsy

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