一例ⅡB期非小細胞肺癌術后患者的循證治療_《中國循證醫學雜志》

作者：

曾文 ¹ , 王小剛 ² ,  岳冀蓉 ³

1. 四川大學華西醫院金卡病房（成都 610041）； 2. 四川省成都市武侯區跳傘塔社區衛生服務中心（成都 610041）；3. 四川大學華西醫院干部老年科（成都 610041）;

關鍵詞：

非小細胞肺癌手術循證治療

DOI：

10.7507/1672-2531.20090242

視頻：

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目的　報告1 例Ⅱ B 期非小細胞肺癌術后患者的循證治療體會。
方法　將針對該例患者臨床問題轉化為可回答的形式，通過計算機檢索Cochrane 圖書館（2009 年第2 期）、PubMed(1970 ～ 2009 年6 月) 和ACP JournalClub（1996 ～ 2009 年6 月），查找并評價當前與非小細胞肺癌Ⅱ B 期治療相關的最佳臨床證據。
結果　現有證據表明，第Ⅰ、Ⅱ期術后輔助性放療、化療并不能改善患者生存率，反而會相對增加患者的死亡風險。按照患者及家屬意愿，該患者術后未進行放化療，而是采用姑息對癥支持治療，效果滿意，好轉出院。
結論　 Ⅰ、Ⅱ期非小細胞肺癌術后放療或化療并不能明顯改善患者生存率，反而會相對增加患者的死亡風險。因而，術后是否采用放療或化療應慎重考慮。

引用本文： 曾文,王小剛,岳冀蓉. 一例ⅡB期非小細胞肺癌術后患者的循證治療. 中國循證醫學雜志, 2009, 09(12): 1336-1338. doi: 10.7507/1672-2531.20090242 復制

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6. Wake B, Taylor R, Sandercock J. Hyperfractionated/accelerated radiotherapy regimens for the treatment of non-small cell lung cancer. A systematic review of clinical and cost-effectiveness. West Midlands Health Technology Assessment Collaboration (WMHTAC), 2002, (DPHE Report No. 35): 65.
7. Pignon JP, Arriagada R, Ihde DC, et al. A Meta-analysis of thoracic radiotherapy for small-cell lung cancer. N Engl J Med, 1992, 327(23): 1618-1624.
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9. Berghmans T, Paesmans M, Meert AP, et al. Survival improvement in resectable non-small cell lung cancer with (neo)adjuvant chemotherapy: results of a meta-analysis of the literature. Lung Cancer, 2005, 49: 13-23.

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一例ⅡB期非小細胞肺癌術后患者的循證治療

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《中國循證醫學雜志》

一例ⅡB期非小細胞肺癌術后患者的循證治療

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