WANG Yubin , TAO Yuhan , ZHANG Yuling , ZHOU Xiaojie , DENG Didan , MAO Hui
  • Department of Respiratory and Critical Care Medicine, West China Hospital, Sichuan University, Chengdu, Sichuan 610041, P.R. China;
MAO Hui, Email: merrymh@yeah.net
Acute pulmonary embolism; stroke volume index; cardiac troponin; simplified pulmonary embolism severity index
10.7507/1671-6205.202601005
Export PDF Favorites Scan Get Citation

Abstract Full text Figures/Tables References Cited by

Objective To explore the prognostic value of stroke volume index (SVI) measured by transthoracic echocardiography (TTE) and cardiac troponin T (cTnT) in hemodynamically stable patients with acute pulmonary embolism (APE), and to establish a novel risk prediction model combining simplified pulmonary embolism severity index (sPESI), SVI and cTnT, and compare its performance with Bova score and modified FAST (mFAST) score. Methods A total of 266 hemodynamically stable patients with confirmed APE from June 2019 to September 2021 were retrospectively included. All patients were followed up for 30 days via outpatient records or telephone. The primary endpoint was adverse outcomes. Results Adverse outcomes occurred in 31 (11.6%) of 266 patients within 30 days. Multivariate analysis showed that both SVI and cTnT were independent predictors of adverse events. The optimal cutoff values of SVI and cTnT were 31.8 mL/m2 and 16.5 ng/L, respectively. The new model divided patients into three risk groups with adverse event rates of 1.3%, 8.5% and 50.0%. The AUC of the new model was 0.80, superior to Bova score and mFAST score. Conclusion SVI and cTnT are independent predictors of adverse prognosis in non-high-risk APE patients. The new model integrating sPESI, SVI and cTnT provides effective risk stratification and has better predictive value than sPESI alone.

Citation： WANG Yubin, TAO Yuhan, ZHANG Yuling, ZHOU Xiaojie, DENG Didan, MAO Hui. Clinical Value of a Novel Scoring Model in Prognostic Evaluation of Low-to Intermediate-Risk Acute Pulmonary Embolism. Chinese Journal of Respiratory and Critical Care Medicine, 2026, 25(6): 385-390. doi: 10.7507/1671-6205.202601005 Copy

Copyright ? the editorial department of Chinese Journal of Respiratory and Critical Care Medicine of West China Medical Publisher. All rights reserved

  • Next Article

    Dual-vessel intervention treatment for massive hemoptysis caused by lung cavitary lesions: A prospective and comparative study