肥胖急性呼吸窘迫綜合征患者的臨床特點_Chinese Journal of Respiratory and Critical Care Medicine

Authors：

張書娟 , 韓麗麗 ,  萬獻堯

大連醫科大學重癥醫學研究所/附屬一院重癥醫學科（遼寧大連 116011）;

Corresponding?author：

萬獻堯, Email: 13322210199@163.com

Keywords：

DOI：

10.7507/1671-6205.201609014

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Citation： 張書娟, 韓麗麗, 萬獻堯. 肥胖急性呼吸窘迫綜合征患者的臨床特點. Chinese Journal of Respiratory and Critical Care Medicine, 2017, 16(4): 421-424. doi: 10.7507/1671-6205.201609014 Copy

1.	徐赫男. 從中國居民營養與慢性病狀況報告看到了什么. 糖尿病臨床, 2016, 10(4): 142-145.
2.	胡雪, 陳月, 鄒大進. 肥胖、糖尿病與腫瘤: 病理生理機制新進展. 中華糖尿病雜志, 2010, 2(5): 321-324.
3.	Smits A, Lopes A, Das N, et al. Surgical morbidity and clinical outcomes in ovarian cancer the role of obesity. BJOG, 2016, 123(2): 300-308.
4.	楊毅, 邱海波. 急性呼吸窘迫綜合征救治: 需要遵循的十大原則. 中華重癥醫學電子雜志, 2015, 1(1): 33-38.
5.	Villar J, Blanco J, Kacmarek RM. Current incidence and outcome of the acute respiratory distress syndrome. Curr Opin Crit Care, 2016, 22(1): 1-6.
6.	Morgan OW, Bramley A, Fowlkes A, et al. Morbid obesity as a risk factor for hospitalization and death due to 2009 pandemic influenza A (H1N1) disease. PLoS One, 2010, 5(3): e9694.
7.	Bautista E, Chotpitayasunondh T, Gao Z, et al. Clinical aspects of pandemic 2009 influenza A (H1N1) virus infection. N Engl J Med, 2010, 362(18): 1708-1719.
8.	楊勝富, 吳東波. 肥胖的流行病學病理生理及治療的研究進展. 中國臨床醫學, 2016, 9(4): 358-362.
9.	Littleton SW. Impact of obesity on respiratory function. Respirology, 2012, 17(1): 43-49.
10.	Hibbert K, Rice M, Malhotra A. Obesity and ARDS. Chest, 2012, 142(3): 785-790.
11.	Ilavská S, Horváthová M, Szabová M, et al. Association between the human immune response and body mass index. Hum Immunol, 2012, 73(5): 480-485.
12.	Lu Y, Van Bever HP, Lim TK, et al. Obesity, asthma prevalence and IL-4: roles of inflammatory cytokines, adiponectin and neuropeptide Y. Pediatr Allergy Immunol, 2015, 26(6): 530-536.
13.	van Harmelen V, Eriksson A, Astr?m G, et al. Vascular peptide endothelin-1 links fat accumulation with alterations of visceral adipocyte lipolysis. Diabetes, 2008, 57(2): 378-386.
14.	Stapleton RD, Dixon AE, Parsons PE, et al. The association between BMI and plasma cytokine levels in patients with acute lung injury. Chest, 2010, 138(3): 568-577.
15.	Gong MN, Bajwa EK, Thompson BT, et al. Body mass index is associated with the development of acute respiratory distress syndrome. Thorax, 2010, 65(1): 44-50.
16.	Fantuzzi G. Adipose tissue, adipokines, and inflammation. J Allergy Clin Immunol, 2005, 115(5): 911-919; quiz 920.
17.	La Cava A, Matarese G. The weight of leptin in immunity. Nat Rev Immunol, 2004, 4(5): 371-379.
18.	Ubags ND, Vernooy JH, Burg E, et al. The role of leptin in the development of pulmonary neutrophilia in infection and acute lung injury. Crit Care Med, 2014, 42(2): e143-151.
19.	Wosu AC, Vélez JC, Barbosa C, et al. The relationship between high risk for obstructive sleep apnea and general and central obesity: findings from a sample of Chilean College Students. ISRN Obes, 2014, 2014: 871681.
20.	El-Solh AA, Aquilina A, Pineda L, et al. Noninvasive ventilation for prevention of post-extubation respiratory failure in obese patients. Eur Respir J, 2006, 28(3): 588-595.
21.	Yoo JW, Synn A, Huh JW, et al. Clinical efficacy of high-flow nasal cannula compared to noninvasive ventilation in patients with post-extubation respiratory failure. Korean J Intern Med, 2016, 31(1): 82-88.
22.	王四海. 壓力-容積曲線低位轉折點選擇呼氣末正壓在 ARDS 應用價值. 臨床肺科雜志, 2014, 19(3): 439-441.
23.	Yadam S, Bihler E, Balaan M. Acute respiratory distress syndrome. Crit Care Nurs Q, 2016, 39(2): 190-195.
24.	Fernandez R, Trenchs X, Klamburg J, et al. Prone positioning in acute respiratory distress syndrome: a multicenter randomized clinical trial. Intensive Care Med, 2008, 34(8): 1487-1491.
25.	Sud S, Friedrich JO, Taccone P, et al. Prone ventilation reduces mortality in patients with acute respiratory failure and severe hypoxemia: systematic review and meta-analysis. Intensive Care Med, 2010, 36(4): 585-599.
26.	Schmidt M, Zogheib E, Rozé H, et al. The PRESERVE mortality risk score and analysis of long-term outcomes after extracorporeal membrane oxygenation for severe acute respiratory distress syndrome. Intensive Care Med, 2013, 39(10): 1704-1713.
27.	Turner KL, Moore FA, Martindale R. Nutrition support for the acute lung injury/adult respiratory distress syndrome patient: a review. Nutr Clin Pract, 2011, 26(1): 14-25.
28.	Bihari S, Bailey M, Bersten AD. Steroids in ARDS: to be or not to be. Intensive Care Med, 2016, 42(5): 931-933.
29.	Bein T, Briegel J, Annane D. Steroids are part of rescue therapy in ARDS patients with refractory hypoxemia: yes. Intensive Care Med, 2016, 42(5): 918-920.
30.	周明. 糖皮質激素在重癥社區獲得性肺炎致急性呼吸窘迫綜合征綜合救治中的應用價值. 臨床醫學工程, 2015, 22(1): 57-58.
31.	郭獻陽, 張明, 陳如杰, 等. 辛伐他汀治療急性呼吸窘迫綜合征的臨床研究. 中國臨床藥理學雜志, 2015, 31(6): 406-408.
32.	喻文, 羅紅敏. 辛伐他汀并不能改善急性呼吸窘迫綜合征患者預后. 中華危重病急救醫學, 2015, 27(3): 208-208.
33.	Truwit JD, Bernard GR, Steingrub J, et al. Rosuvastatin for sepsis-associated acute respiratory distress syndrome. N Engl J Med, 2014, 370(23): 2191-2200.
34.	唐芳華, 黎艷. 體位護理對減少呼吸機相關性肺炎發生的效果觀察. 中國臨床新醫學, 2015, (12): 1193-1195.
35.	O'Brien JM, Phillips GS, Ali NA, et al. Body mass index is independently associated with hospital mortality in mechanically ventilated adults with acute lung injury. Crit Care Med, 2006, 34(3): 738-744.
36.	Soto GJ, Frank AJ, Christiani DC, et al. Body mass index and acute kidney injury in the acute respiratory distress syndrome. Crit Care Med, 2012, 40(9): 2601-2608.
37.	O'Brien JM, Welsh CH, Fish RH, et al. Excess body weight is not independently associated with outcome in mechanically ventilated patients with acute lung injury. Ann Intern Med, 2004, 140(5): 338-345.
38.	Morris AE, Stapleton RD, Rubenfeld GD, et al. The association between body mass index and clinical outcomes in acute lung injury. Chest, 2007, 131(2): 342-348.
39.	Schell-Chaple HM, Puntillo KA, Matthay MA, et al. Body temperature and mortality in patients with acute respiratory distress syndrome. Am J Crit Care, 2015, 24(1): 15-23.
40.	李缺缺, 張久之, 萬獻堯. 老年急性呼吸窘迫綜合征的特點. 中國呼吸與危重監護雜志, 2013, 12(5): 530-532.
41.	McIntyre LA, Moher D, Fergusson DA, et al. Efficacy of mesenchymal stromal cell therapy for acute lung injury in preclinical animal models: a systematic review. PLoS One, 2016, 11(1): e0147170.

1. 徐赫男. 從中國居民營養與慢性病狀況報告看到了什么. 糖尿病臨床, 2016, 10(4): 142-145.
2. 胡雪, 陳月, 鄒大進. 肥胖、糖尿病與腫瘤: 病理生理機制新進展. 中華糖尿病雜志, 2010, 2(5): 321-324.
3. Smits A, Lopes A, Das N, et al. Surgical morbidity and clinical outcomes in ovarian cancer the role of obesity. BJOG, 2016, 123(2): 300-308.
4. 楊毅, 邱海波. 急性呼吸窘迫綜合征救治: 需要遵循的十大原則. 中華重癥醫學電子雜志, 2015, 1(1): 33-38.
5. Villar J, Blanco J, Kacmarek RM. Current incidence and outcome of the acute respiratory distress syndrome. Curr Opin Crit Care, 2016, 22(1): 1-6.
6. Morgan OW, Bramley A, Fowlkes A, et al. Morbid obesity as a risk factor for hospitalization and death due to 2009 pandemic influenza A (H1N1) disease. PLoS One, 2010, 5(3): e9694.
7. Bautista E, Chotpitayasunondh T, Gao Z, et al. Clinical aspects of pandemic 2009 influenza A (H1N1) virus infection. N Engl J Med, 2010, 362(18): 1708-1719.
8. 楊勝富, 吳東波. 肥胖的流行病學病理生理及治療的研究進展. 中國臨床醫學, 2016, 9(4): 358-362.
9. Littleton SW. Impact of obesity on respiratory function. Respirology, 2012, 17(1): 43-49.
10. Hibbert K, Rice M, Malhotra A. Obesity and ARDS. Chest, 2012, 142(3): 785-790.
11. Ilavská S, Horváthová M, Szabová M, et al. Association between the human immune response and body mass index. Hum Immunol, 2012, 73(5): 480-485.
12. Lu Y, Van Bever HP, Lim TK, et al. Obesity, asthma prevalence and IL-4: roles of inflammatory cytokines, adiponectin and neuropeptide Y. Pediatr Allergy Immunol, 2015, 26(6): 530-536.
13. van Harmelen V, Eriksson A, Astr?m G, et al. Vascular peptide endothelin-1 links fat accumulation with alterations of visceral adipocyte lipolysis. Diabetes, 2008, 57(2): 378-386.
14. Stapleton RD, Dixon AE, Parsons PE, et al. The association between BMI and plasma cytokine levels in patients with acute lung injury. Chest, 2010, 138(3): 568-577.
15. Gong MN, Bajwa EK, Thompson BT, et al. Body mass index is associated with the development of acute respiratory distress syndrome. Thorax, 2010, 65(1): 44-50.
16. Fantuzzi G. Adipose tissue, adipokines, and inflammation. J Allergy Clin Immunol, 2005, 115(5): 911-919; quiz 920.
17. La Cava A, Matarese G. The weight of leptin in immunity. Nat Rev Immunol, 2004, 4(5): 371-379.
18. Ubags ND, Vernooy JH, Burg E, et al. The role of leptin in the development of pulmonary neutrophilia in infection and acute lung injury. Crit Care Med, 2014, 42(2): e143-151.
19. Wosu AC, Vélez JC, Barbosa C, et al. The relationship between high risk for obstructive sleep apnea and general and central obesity: findings from a sample of Chilean College Students. ISRN Obes, 2014, 2014: 871681.
20. El-Solh AA, Aquilina A, Pineda L, et al. Noninvasive ventilation for prevention of post-extubation respiratory failure in obese patients. Eur Respir J, 2006, 28(3): 588-595.
21. Yoo JW, Synn A, Huh JW, et al. Clinical efficacy of high-flow nasal cannula compared to noninvasive ventilation in patients with post-extubation respiratory failure. Korean J Intern Med, 2016, 31(1): 82-88.
22. 王四海. 壓力-容積曲線低位轉折點選擇呼氣末正壓在 ARDS 應用價值. 臨床肺科雜志, 2014, 19(3): 439-441.
23. Yadam S, Bihler E, Balaan M. Acute respiratory distress syndrome. Crit Care Nurs Q, 2016, 39(2): 190-195.
24. Fernandez R, Trenchs X, Klamburg J, et al. Prone positioning in acute respiratory distress syndrome: a multicenter randomized clinical trial. Intensive Care Med, 2008, 34(8): 1487-1491.
25. Sud S, Friedrich JO, Taccone P, et al. Prone ventilation reduces mortality in patients with acute respiratory failure and severe hypoxemia: systematic review and meta-analysis. Intensive Care Med, 2010, 36(4): 585-599.
26. Schmidt M, Zogheib E, Rozé H, et al. The PRESERVE mortality risk score and analysis of long-term outcomes after extracorporeal membrane oxygenation for severe acute respiratory distress syndrome. Intensive Care Med, 2013, 39(10): 1704-1713.
27. Turner KL, Moore FA, Martindale R. Nutrition support for the acute lung injury/adult respiratory distress syndrome patient: a review. Nutr Clin Pract, 2011, 26(1): 14-25.
28. Bihari S, Bailey M, Bersten AD. Steroids in ARDS: to be or not to be. Intensive Care Med, 2016, 42(5): 931-933.
29. Bein T, Briegel J, Annane D. Steroids are part of rescue therapy in ARDS patients with refractory hypoxemia: yes. Intensive Care Med, 2016, 42(5): 918-920.
30. 周明. 糖皮質激素在重癥社區獲得性肺炎致急性呼吸窘迫綜合征綜合救治中的應用價值. 臨床醫學工程, 2015, 22(1): 57-58.
31. 郭獻陽, 張明, 陳如杰, 等. 辛伐他汀治療急性呼吸窘迫綜合征的臨床研究. 中國臨床藥理學雜志, 2015, 31(6): 406-408.
32. 喻文, 羅紅敏. 辛伐他汀并不能改善急性呼吸窘迫綜合征患者預后. 中華危重病急救醫學, 2015, 27(3): 208-208.
33. Truwit JD, Bernard GR, Steingrub J, et al. Rosuvastatin for sepsis-associated acute respiratory distress syndrome. N Engl J Med, 2014, 370(23): 2191-2200.
34. 唐芳華, 黎艷. 體位護理對減少呼吸機相關性肺炎發生的效果觀察. 中國臨床新醫學, 2015, (12): 1193-1195.
35. O'Brien JM, Phillips GS, Ali NA, et al. Body mass index is independently associated with hospital mortality in mechanically ventilated adults with acute lung injury. Crit Care Med, 2006, 34(3): 738-744.
36. Soto GJ, Frank AJ, Christiani DC, et al. Body mass index and acute kidney injury in the acute respiratory distress syndrome. Crit Care Med, 2012, 40(9): 2601-2608.
37. O'Brien JM, Welsh CH, Fish RH, et al. Excess body weight is not independently associated with outcome in mechanically ventilated patients with acute lung injury. Ann Intern Med, 2004, 140(5): 338-345.
38. Morris AE, Stapleton RD, Rubenfeld GD, et al. The association between body mass index and clinical outcomes in acute lung injury. Chest, 2007, 131(2): 342-348.
39. Schell-Chaple HM, Puntillo KA, Matthay MA, et al. Body temperature and mortality in patients with acute respiratory distress syndrome. Am J Crit Care, 2015, 24(1): 15-23.
40. 李缺缺, 張久之, 萬獻堯. 老年急性呼吸窘迫綜合征的特點. 中國呼吸與危重監護雜志, 2013, 12(5): 530-532.
41. McIntyre LA, Moher D, Fergusson DA, et al. Efficacy of mesenchymal stromal cell therapy for acute lung injury in preclinical animal models: a systematic review. PLoS One, 2016, 11(1): e0147170.

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肥胖急性呼吸窘迫綜合征患者的臨床特點

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