支氣管哮喘-慢性阻塞性肺疾病重疊綜合征的診治進展_《中國呼吸與危重監護雜志》

作者：

上海交通大學附屬瑞金醫院北院呼吸科(上海 201821);

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DOI：

10.7507/1671-6205.2014052

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引用本文： 張海琴, 程齊儉, 萬歡英. 支氣管哮喘-慢性阻塞性肺疾病重疊綜合征的診治進展. 中國呼吸與危重監護雜志, 2013, 12(2): 219-222. doi: 10.7507/1671-6205.2014052 復制

1.	Barnes PJ.Mechanisms in COPD: differences from asthma.Chest,2000,117(2suppl): 10S-14S.
2.	Shaya FT,Dongyi D,Akazawa MO,et al.Burden of concomitant asthma and COPD in a Medicaid population.Chest,2008,134: 14-19.
3.	Louie S,Zeki AA,Schivo M,et al.The asthma-chronic obstructive pulmonary disease overlap syndrome:pharmacotherapeutic considerations.Expert Rev Clin Pharmacol,2013,6:197-219.
4.	Gibson PG,Simpson JL.The overlap syndrome of asthma and COPD: what are its features andhow important is it?Thorax,2009,64:728-735.
5.	de Marco R,Pesce G,Marcon A,et al.The Coexistence of Asthma and Chronic Obstructive Pulmonary Disease (COPD):Prevalence and Risk Factors in Young,Middle-aged and Elderly People from theGeneral Population.PLoS One,2013,8:e62985.
6.	Nakawah MO,Hawkins C,Barbandi F.Asthma,Chronic Obstructive PulmonaryDisease (COPD),and the OverlapSyndrome.J Am Board Fam Med,2013,26:470-477.
7.	Hardin M,Silverman EK,Barr RG,et al.COPD Gene Investigators.The clinical features of the overlap between COPD and asthma.Respir Res,2011,12:127.
8.	Bleecker ES.Similarities and differences in asthma and COPD.The Dutch hypothesis.Chest,2004,126: 93-95.
9.	Gibson PG,Simpson JL.The overlap syndrome of asthma and COPD: what are its features and how important is it? Thorax,2009,64:728-735.
10.	劉宇鵬,張齊武.支氣管哮喘與慢性阻塞性肺疾病重疊現象的研究進展.臨床肺科雜志,2011,16:1752-1753.
11.	Eden E.Asthma and COPD in alpha-1 antitrypsin deficiency.Evidencefor the Dutch hypothesis.COPD,2010,7: 366-374.
12.	Fabbri LM,Romagnoli M,Corbetta L,et al.Differences in Airway Inflammation in Patients with Fixed Airflow Obstruction Due to Asthma or Chronic Obstructive Pulmonary Disease.Am J Respir Crit Care Med,2003,167: 418-424.
13.	Kim SR,Rhee YK.Overlap Between Asthma and COPD: Where the Two Diseases Converge.Allergy Asthma Immunol Res,2010,2: 209-214.
14.	Lamblin C,Gosset P,Tillie-Leblond I,et al.Bronchial neutrophilia in patients with noninfectious status asthmaticus.Am J Respir Crit Care Med,1998,157: 394-402.
15.	Zeki AA,Schivo M,Chan A,et al.The Asthma-COPD Overlap Syndrome: A Common Clinical Problem in the Elderly.J Allergy (Cairo). 2011 (2011), Article ID 861926.
16.	李坤營,廉桃梅,馬利軍.氣道重疊綜合征研究新進展.中華哮喘雜志:電子版,2013,7:115-119.
17.	Siva R,Green RH,Brightling CE,et al.Eosinophilic airway inflammationandexacerbations of COPD: a randomized controlled trial.Eur Respir J,2007,29: 906-913.
18.	Kitaguchi Y,Komatsu Y,Fujimoto Y,et al.Sputum eosinophilia can predict responsiveness to inhaled corticosteroid treatment inpatients with overlap syndrome of COPD and asthma.Int J Chron Obstruct Pulmon Dis,2012,7:283-289.
19.	Chatila TA.Interleukin-4receptor signaling pathways in asthma pathogenesis.Trends Mol Med,2004,10: 493-499.
20.	Bullens DM,Truyen E,Coteur L,et al.IL-17 mRNA in sputum ofasthmatic patients: linking T cell driven inflammation and granulocyticinflux? Respir Res,2006,7:135.
21.	Barnes PJ.Targeting the epigenome in the treatment of asthma and chronic obstructive pulmonary disease.Proc Am Thorac Soc,2009,6: 693-696.
22.	Ito K,Ito M,Elliott WM,et al.Decreased histone deacetylas activity in chronic obstructive pulmonary disease.N Engl J Med,2005,352:1967-1976.
23.	Hew M,Bhavsar P,Torrego A,et al.Relative corticosteroid insensitivity of peripheral blood mononuclear cells in severe asthma.Am J Respir Crit Care Med,2006,174: 134-141.
24.	Zhou Y,Schneider DJ,Blackburn MR.Adenosine signaling and theregulation of chronic lung disease. J Pharmacol Ther,2009,123:105-116.
25.	Caruso M,Tringali G,Polosa R.Evidence for a functional contribution of adenosine signalling ininflammatory airway diseases.Immunol Endocr Metab Agents Med Chem,2007,7:286-297.
26.	Spurzem JR,Rennard SI.Pathogenesis of COPD.Semin RespirCrit Care Med,2005,26: 142-153.
27.	Sumi Y,Hamid Q.Airway remodeling in asthma.Allergol Int,2007,56: 341-348.
28.	Postma DS,Kerkhof M,Boezen HM,et al.Asthma and chronic obstructive pulmonary disease: common genes,common environments? Am J Respir Crit Care Med,2011,183:1588-1594.
29.	Kauppi P,Kupiainen H,Lindqvist A,et al.Overlap syndrome of asthma and COPD predicts low quality of life.J Asthma,2011,48:279-285.
30.	Shaya FT,Dongyi D,Akazawa MO,et al.Burden of concomitant asthma and COPD in a Medicaid population.Chest,2008,134: 14-19.
31.	孫永昌.支氣管哮喘-慢性阻塞性肺疾病重疊綜合征.中華哮喘雜志:電子版,2012,6:306-308.
32.	Miravitlles M,Soler-Cataluña JJ,Calle M,et al.[Spanish COPD Guidelines (GesEPOC): pharmacological treatment of stable COPD.Aten Primaria, 2012,44:425-437. ［33]Magnussen H,Bugnas B,Van Noord J,et al.Improvements with tiotropium in COPD patients with concomitant asthma.Respir Med,2008,102: 50-56.
33.	Peters SP,Kunselman SJ,Icitovic N,et al.Tiotropium bromide step-up therapy for adults with uncontrolled asthma.N Engl J Med,2010,363:1715-1726.

1. Barnes PJ.Mechanisms in COPD: differences from asthma.Chest,2000,117(2suppl): 10S-14S.
2. Shaya FT,Dongyi D,Akazawa MO,et al.Burden of concomitant asthma and COPD in a Medicaid population.Chest,2008,134: 14-19.
3. Louie S,Zeki AA,Schivo M,et al.The asthma-chronic obstructive pulmonary disease overlap syndrome:pharmacotherapeutic considerations.Expert Rev Clin Pharmacol,2013,6:197-219.
4. Gibson PG,Simpson JL.The overlap syndrome of asthma and COPD: what are its features andhow important is it?Thorax,2009,64:728-735.
5. de Marco R,Pesce G,Marcon A,et al.The Coexistence of Asthma and Chronic Obstructive Pulmonary Disease (COPD):Prevalence and Risk Factors in Young,Middle-aged and Elderly People from theGeneral Population.PLoS One,2013,8:e62985.
6. Nakawah MO,Hawkins C,Barbandi F.Asthma,Chronic Obstructive PulmonaryDisease (COPD),and the OverlapSyndrome.J Am Board Fam Med,2013,26:470-477.
7. Hardin M,Silverman EK,Barr RG,et al.COPD Gene Investigators.The clinical features of the overlap between COPD and asthma.Respir Res,2011,12:127.
8. Bleecker ES.Similarities and differences in asthma and COPD.The Dutch hypothesis.Chest,2004,126: 93-95.
9. Gibson PG,Simpson JL.The overlap syndrome of asthma and COPD: what are its features and how important is it? Thorax,2009,64:728-735.
10. 劉宇鵬,張齊武.支氣管哮喘與慢性阻塞性肺疾病重疊現象的研究進展.臨床肺科雜志,2011,16:1752-1753.
11. Eden E.Asthma and COPD in alpha-1 antitrypsin deficiency.Evidencefor the Dutch hypothesis.COPD,2010,7: 366-374.
12. Fabbri LM,Romagnoli M,Corbetta L,et al.Differences in Airway Inflammation in Patients with Fixed Airflow Obstruction Due to Asthma or Chronic Obstructive Pulmonary Disease.Am J Respir Crit Care Med,2003,167: 418-424.
13. Kim SR,Rhee YK.Overlap Between Asthma and COPD: Where the Two Diseases Converge.Allergy Asthma Immunol Res,2010,2: 209-214.
14. Lamblin C,Gosset P,Tillie-Leblond I,et al.Bronchial neutrophilia in patients with noninfectious status asthmaticus.Am J Respir Crit Care Med,1998,157: 394-402.
15. Zeki AA,Schivo M,Chan A,et al.The Asthma-COPD Overlap Syndrome: A Common Clinical Problem in the Elderly.J Allergy (Cairo). 2011 (2011), Article ID 861926.
16. 李坤營,廉桃梅,馬利軍.氣道重疊綜合征研究新進展.中華哮喘雜志:電子版,2013,7:115-119.
17. Siva R,Green RH,Brightling CE,et al.Eosinophilic airway inflammationandexacerbations of COPD: a randomized controlled trial.Eur Respir J,2007,29: 906-913.
18. Kitaguchi Y,Komatsu Y,Fujimoto Y,et al.Sputum eosinophilia can predict responsiveness to inhaled corticosteroid treatment inpatients with overlap syndrome of COPD and asthma.Int J Chron Obstruct Pulmon Dis,2012,7:283-289.
19. Chatila TA.Interleukin-4receptor signaling pathways in asthma pathogenesis.Trends Mol Med,2004,10: 493-499.
20. Bullens DM,Truyen E,Coteur L,et al.IL-17 mRNA in sputum ofasthmatic patients: linking T cell driven inflammation and granulocyticinflux? Respir Res,2006,7:135.
21. Barnes PJ.Targeting the epigenome in the treatment of asthma and chronic obstructive pulmonary disease.Proc Am Thorac Soc,2009,6: 693-696.
22. Ito K,Ito M,Elliott WM,et al.Decreased histone deacetylas activity in chronic obstructive pulmonary disease.N Engl J Med,2005,352:1967-1976.
23. Hew M,Bhavsar P,Torrego A,et al.Relative corticosteroid insensitivity of peripheral blood mononuclear cells in severe asthma.Am J Respir Crit Care Med,2006,174: 134-141.
24. Zhou Y,Schneider DJ,Blackburn MR.Adenosine signaling and theregulation of chronic lung disease. J Pharmacol Ther,2009,123:105-116.
25. Caruso M,Tringali G,Polosa R.Evidence for a functional contribution of adenosine signalling ininflammatory airway diseases.Immunol Endocr Metab Agents Med Chem,2007,7:286-297.
26. Spurzem JR,Rennard SI.Pathogenesis of COPD.Semin RespirCrit Care Med,2005,26: 142-153.
27. Sumi Y,Hamid Q.Airway remodeling in asthma.Allergol Int,2007,56: 341-348.
28. Postma DS,Kerkhof M,Boezen HM,et al.Asthma and chronic obstructive pulmonary disease: common genes,common environments? Am J Respir Crit Care Med,2011,183:1588-1594.
29. Kauppi P,Kupiainen H,Lindqvist A,et al.Overlap syndrome of asthma and COPD predicts low quality of life.J Asthma,2011,48:279-285.
30. Shaya FT,Dongyi D,Akazawa MO,et al.Burden of concomitant asthma and COPD in a Medicaid population.Chest,2008,134: 14-19.
31. 孫永昌.支氣管哮喘-慢性阻塞性肺疾病重疊綜合征.中華哮喘雜志:電子版,2012,6:306-308.
32. Miravitlles M,Soler-Cataluña JJ,Calle M,et al.[Spanish COPD Guidelines (GesEPOC): pharmacological treatment of stable COPD.Aten Primaria, 2012,44:425-437. ［33]Magnussen H,Bugnas B,Van Noord J,et al.Improvements with tiotropium in COPD patients with concomitant asthma.Respir Med,2008,102: 50-56.
33. Peters SP,Kunselman SJ,Icitovic N,et al.Tiotropium bromide step-up therapy for adults with uncontrolled asthma.N Engl J Med,2010,363:1715-1726.

《中國呼吸與危重監護雜志》

支氣管哮喘-慢性阻塞性肺疾病重疊綜合征的診治進展

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《中國呼吸與危重監護雜志》

支氣管哮喘-慢性阻塞性肺疾病重疊綜合征的診治進展

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