Research progress of residual nodules after thermal ablation for benign thyroid nodules_CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY

Authors：

 YE Liang , SUN Ke , ZHANG Chao , LIU Xiping , LI Zhidong , XU Shaozhong

The First Department of General Surgery, Zhuzhou Central Hospital, Zhuzhou, Hunan 412000, P. R. China;

Corresponding?author：

YE Liang, Email: 281737368@qq.com

Keywords：

benign nodule of thyroid; thermal ablation; review

DOI：

10.7507/1007-9424.201904049

Video：

Export PDF Favorites Scan Get Citation

Abstract Full text Figures/Tables Video References Cited by

Objective To investigate the research progress of residual nodules after thermal ablation for benign thyroid nodules.Methods The domestic and foreign guidelines and consensus on the treatment of benign thyroid nodules were collected, and the indications for thermal ablation were summarized. The causes of residual nodules after ablation were analyzed, the characteristics of residual nodules were evaluated through multiple approaches, and the follow-up treatment measures were summarized.Results The indications of thermal ablation of benign thyroid nodules were different at home and abroad. The causes of residual nodules included slow absorption after ablation and incomplete ablation. Among the evaluation methods of residual nodules, the nodules volume reduction rate was the evaluation standard of short-term efficacy, contrast-enhanced ultrasound was the best method, color Doppler blood color distributionwas the most commonly used method, elastic imaging was a valuable method, and puncture pathology biopsy was an important standard. Reablation and surgical resection were the follow-up treatments for residual nodules.Conclusions As a new technique, thermal ablation of benign thyroid nodules has some advantages, but it is flooding at present. In the future, it is necessary to standardize indications, improve the efficiency of first ablation, attach importance to pathological complete ablation, and reasonably evaluate the treatment of residual nodules, so that thermal ablation of benign thyroid nodules could reflect rationality, safety, and efficiency, and give full play to its advantages, so as to serve patients better and have better application prospects.

Citation： YE Liang, SUN Ke, ZHANG Chao, LIU Xiping, LI Zhidong, XU Shaozhong. Research progress of residual nodules after thermal ablation for benign thyroid nodules. CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY, 2019, 26(11): 1361-1366. doi: 10.7507/1007-9424.201904049 Copy

1.	金鑫荔, 盧偉. 甲狀腺結節射頻及微波消融治療—現狀及存在問題. 臨床放射學雜志, 2017, 36(2): 295-297.
2.	吳震中, 章建全. 甲狀腺結節微波熱消融治療的臨床進展. 中國介入影像與治療學, 2016, 13(12): 772-774.
3.	中華醫學會內分泌學分會, 中華醫學會外科學分會, 中國抗癌協會頭頸腫瘤專業委員會, 等. 甲狀腺結節和分化型甲狀腺癌診治指南. 中國腫瘤臨床, 2012, 39(17): 1249-1272.
4.	Haugen BR, Alexander EK, Bible KC, et al. 2015 American Thyroid Association Management Guidelines for Adult Patients with Thyroid Nodules and Differentiated Thyroid Cancer: The American Thyroid Association Guidelines Task Force on Thyroid Nodules and Differentiated Thyroid Cancer. Thyroid, 2016, 26(1): 1-133.
5.	方建強, 趙維安, 李慶. 超聲引導微波消融術治療甲狀腺良性結節的療效與安全性分析. 中國臨床醫學影像雜志, 2019, 30(4): 250-252, 266.
6.	胡云飛, 蔡雨, 趙勝. 超聲介導微波消融術與傳統開放手術比較治療甲狀腺良性結節療效的系統評價. 中國循證醫學雜志, 2019, 19(3): 338-347.
7.	Baek JH, Na DG, Lee JH, et al. Korean society of thyroid radiology recommendations for radiofrequency ablation of thyroid nodules. Korean Society of Thyroid Radiology, 2009. [2016-06-01]. http://thyroidimaging.kr/.
8.	Na DG, Lee JH, Jung SL, et al. Radiofrequency ablation of benign thyroid nodules and recurrent thyroid cancers: consensus statement and recommendations. Korean J Radiol, 2012, 13(2): 117-125.
9.	Kim JH, Baek JH, Lim HK, et al. 2017 Thyroid Radiofrequency Ablation Guideline: Korean Society of Thyroid Radiology. Korean J Radiol, 2018, 19(4): 632-655.
10.	Garberoglio R, Aliberti C, Appetecchia M, et al. Radiofrequency ablation for thyroid nodules: which indications? The first Italian opinion statement. J Ultrasound, 2015, 18(4): 423-430.
11.	刁暢, 程若川. 消融治療在甲狀腺結節治療中的誤區與思考. 醫學與哲學, 2015, 36(20): 16-21.
12.	浙江省抗癌協會甲狀腺腫瘤專業委員會. 甲狀腺良性結節、微小癌及頸部轉移性淋巴結熱消融治療浙江省專家共識 (2015版). 中國普通外科雜志, 2016, 25(7): 944-946.
13.	中國醫師協會甲狀腺腫瘤消融治療技術專家組, 中國抗癌協會甲狀腺癌專業委員會, 中國醫師協會介入醫師分會超聲介入專業委員會, 等. 甲狀腺良性結節、微小癌及頸部轉移性淋巴結熱消融治療專家共識 (2018版). 中國腫瘤, 2018, 27(10): 768-773.
14.	王宇思. 超聲引導下經皮微波消融術在甲狀腺良性結節治療中的應用效果觀察. 中國療養醫學, 2018, 27(6): 611-612.
15.	蘇鴻輝, 吳玉帆, 陳耿臻. 超聲引導下經皮微波消融治療甲狀腺良性結節的并發癥. 現代醫院, 2017, 17(1): 95-98.
16.	張波, 高瓊, 李小毅, 等. 甲狀腺結節射頻消融的歷史、現狀及展望. 重慶醫科大學學報, 2018, 43(12): 1537-1541.
17.	Jung SL, Baek JH, Lee JH, et al. Efficacy and safety of radiofrequency ablation for benign thyroid nodules: a prospective multicenter study. Korean J Radiol, 2018, 19(1): 167-174.
18.	Liu YJ, Qian LX, Liu D, et al. Ultrasound-guided microwave ablation in the treatment of benign thyroid nodules in 435 patients. Exp Biol Med (Maywood), 2017, 242(15): 1515-1523.
19.	Sartori S, Mauri G, Tombesi P, et al. Ultrasound-guided percutaneous laser ablation is safe and effective in the treatment of small renal tumors in patients at increased bleeding risk. Int J Hyperthermia, 2018, 35(1): 19-25.
20.	Mauri G, Nicosia L, Della Vigna P, et al. Percutaneous laser ablation for benign and malignant thyroid diseases. Ultrasonography, 2019, 38(1): 25-36.
21.	Lim HK, Lee JH, Ha EJ, et al. Radiofrequency ablation of benign non-functioning thyroid nodules: 4-year follow-up results for 111 patients. Eur Radiol, 2013, 23(4): 1044-1049.
22.	Valcavi R, Riganti F, Bertani A, et al. Percutaneous laser ablation of cold benign thyroid nodules: a 3-year follow-up study in 122 patients. Thyroid, 2010, 20(11): 1253-1261.
23.	劉玉輝, 王文玲, 王毅, 等. 超聲引導下經皮微波消融甲狀腺術后復發結節的臨床研究. 臨床耳鼻咽喉頭頸外科雜志, 2015, 29(7): 622-624.
24.	閆磊, 章建全, 陳紅瓊, 等. 甲狀腺結節微波消融治療后6個月消融區細胞活性的酶組織化學檢測. 第二軍醫大學學報, 2019, 40(1): 20-24.
25.	Rahal Junior A, Falsarella PM, Mendes GF, et al. Percutaneous laser ablation of benign thyroid nodules: a one year follow-up study. Einstein (Sao Paulo), 2018, 16(4): eAO4279.
26.	馬樹花, 周平. 超聲引導下熱消融治療甲狀腺結節的應用. 中外醫學研究, 2014, 12(13): 146-147, 148.
27.	郝少龍, 馬紀紅, 姜立新, 等. 熱消融術在甲狀腺結節微創治療中的應用進展. 中華普通外科學文獻: 電子版, 2016, 10(1): 77-80.
28.	章建全. 甲狀腺結節經皮射頻、微波消融治療指南. 中國醫刊, 2014, 49: 90-96.
29.	Lee CU, Kim SJ, Sung JY, et al. Needle track tumor seeding after radiofrequency ablation of a thyroid tumor. Jpn J Radiol, 2014, 32(11): 661-663.
30.	張恒. 甲狀腺結節射頻消融治療的效果探析. 中國醫藥指南, 2015, 13(17): 279-280.
31.	李建如, 羅渝昆. 射頻消融技術在甲狀腺結節治療中的應用. 解放軍醫學院學報, 2016, 37(7): 807-809.
32.	紀莉, 吳鳳林, 婁雪峰, 等. 超聲彈性成像評估甲狀腺良性結節射頻消融效果的價值探討. 中國超聲醫學雜志, 2014, 30(12): 1071-1073.
33.	刁宗平, 章建全, 盛建國, 等. 超聲彈性成像在甲狀腺良性結節射頻消融中的應用價值及相關動態分析. 第二軍醫大學學報, 2017, 38(7): 947-950.
34.	孔月, 程志剛, 韓治宇, 等. 組織彈性定量分析在甲狀腺良性病灶微波消融治療中的應用價值. 中國超聲醫學雜志, 2014, 30(6): 489-492.
35.	Huh JY, Baek JH, Choi H, et al. Symptomatic benign thyroid nodules: efficacy of additional radiofrequency ablation treatment session—prospective randomized study. Radiology, 2012, 263(3): 909-916.
36.	董文武, 張浩, 張平, 等. 甲狀腺乳頭狀癌射頻消融治療后再手術5例臨床分析. 中國實用外科雜志, 2015, 35(6): 653-655.
37.	楊映弘, 顏璟, 吳艷軍, 等. 液體隔離帶法與杠桿撬離法在超聲引導下甲狀腺微波消融術中的應用比較. 中國現代普通外科進展, 2018, 21(1): 28-30.
38.	章建全, 盛建國, 刁宗平, 等. 液體隔離法在頸部結節性病變經皮熱消融治療中的應用. 第二軍醫大學學報, 2014, 35(10): 1045-1052.
39.	孔月, 程志剛, 韓治宇, 等. 移動消融技術在微波消融治療甲狀腺良性結節中的應用價值. 解放軍醫學院學報, 2014, 35(7): 660-662, 691.
40.	Ahn HS, Kim SJ, Park SH, et al. Radiofrequency ablation of benign thyroid nodules: evaluation of the treatment efficacy using ultrasonography. Ultrasonography, 2016, 35(3): 244-252.
41.	單海琳, 鄒大中, 邵清. 超聲造影評價甲狀腺結節激光消融療效的應用. 東南大學學報: 醫學版, 2016, 35(1): 36-40.
42.	Yue W, Wang S, Wang B, et al. Ultrasound guided percutaneous microwave ablation of benign thyroid nodules: safety and imaging follow-up in 222 patients. Eur J Radiol, 2013, 82(1): e11-e16.
43.	曲明, 楊強, 尹惠生, 等. 超聲引導下甲狀腺結節微波消融術圍手術期處理. 實用醫藥雜志, 2016, 33(7): 599-602.

1. 金鑫荔, 盧偉. 甲狀腺結節射頻及微波消融治療—現狀及存在問題. 臨床放射學雜志, 2017, 36(2): 295-297.
2. 吳震中, 章建全. 甲狀腺結節微波熱消融治療的臨床進展. 中國介入影像與治療學, 2016, 13(12): 772-774.
3. 中華醫學會內分泌學分會, 中華醫學會外科學分會, 中國抗癌協會頭頸腫瘤專業委員會, 等. 甲狀腺結節和分化型甲狀腺癌診治指南. 中國腫瘤臨床, 2012, 39(17): 1249-1272.
4. Haugen BR, Alexander EK, Bible KC, et al. 2015 American Thyroid Association Management Guidelines for Adult Patients with Thyroid Nodules and Differentiated Thyroid Cancer: The American Thyroid Association Guidelines Task Force on Thyroid Nodules and Differentiated Thyroid Cancer. Thyroid, 2016, 26(1): 1-133.
5. 方建強, 趙維安, 李慶. 超聲引導微波消融術治療甲狀腺良性結節的療效與安全性分析. 中國臨床醫學影像雜志, 2019, 30(4): 250-252, 266.
6. 胡云飛, 蔡雨, 趙勝. 超聲介導微波消融術與傳統開放手術比較治療甲狀腺良性結節療效的系統評價. 中國循證醫學雜志, 2019, 19(3): 338-347.
7. Baek JH, Na DG, Lee JH, et al. Korean society of thyroid radiology recommendations for radiofrequency ablation of thyroid nodules. Korean Society of Thyroid Radiology, 2009. [2016-06-01]. http://thyroidimaging.kr/.
8. Na DG, Lee JH, Jung SL, et al. Radiofrequency ablation of benign thyroid nodules and recurrent thyroid cancers: consensus statement and recommendations. Korean J Radiol, 2012, 13(2): 117-125.
9. Kim JH, Baek JH, Lim HK, et al. 2017 Thyroid Radiofrequency Ablation Guideline: Korean Society of Thyroid Radiology. Korean J Radiol, 2018, 19(4): 632-655.
10. Garberoglio R, Aliberti C, Appetecchia M, et al. Radiofrequency ablation for thyroid nodules: which indications? The first Italian opinion statement. J Ultrasound, 2015, 18(4): 423-430.
11. 刁暢, 程若川. 消融治療在甲狀腺結節治療中的誤區與思考. 醫學與哲學, 2015, 36(20): 16-21.
12. 浙江省抗癌協會甲狀腺腫瘤專業委員會. 甲狀腺良性結節、微小癌及頸部轉移性淋巴結熱消融治療浙江省專家共識 (2015版). 中國普通外科雜志, 2016, 25(7): 944-946.
13. 中國醫師協會甲狀腺腫瘤消融治療技術專家組, 中國抗癌協會甲狀腺癌專業委員會, 中國醫師協會介入醫師分會超聲介入專業委員會, 等. 甲狀腺良性結節、微小癌及頸部轉移性淋巴結熱消融治療專家共識 (2018版). 中國腫瘤, 2018, 27(10): 768-773.
14. 王宇思. 超聲引導下經皮微波消融術在甲狀腺良性結節治療中的應用效果觀察. 中國療養醫學, 2018, 27(6): 611-612.
15. 蘇鴻輝, 吳玉帆, 陳耿臻. 超聲引導下經皮微波消融治療甲狀腺良性結節的并發癥. 現代醫院, 2017, 17(1): 95-98.
16. 張波, 高瓊, 李小毅, 等. 甲狀腺結節射頻消融的歷史、現狀及展望. 重慶醫科大學學報, 2018, 43(12): 1537-1541.
17. Jung SL, Baek JH, Lee JH, et al. Efficacy and safety of radiofrequency ablation for benign thyroid nodules: a prospective multicenter study. Korean J Radiol, 2018, 19(1): 167-174.
18. Liu YJ, Qian LX, Liu D, et al. Ultrasound-guided microwave ablation in the treatment of benign thyroid nodules in 435 patients. Exp Biol Med (Maywood), 2017, 242(15): 1515-1523.
19. Sartori S, Mauri G, Tombesi P, et al. Ultrasound-guided percutaneous laser ablation is safe and effective in the treatment of small renal tumors in patients at increased bleeding risk. Int J Hyperthermia, 2018, 35(1): 19-25.
20. Mauri G, Nicosia L, Della Vigna P, et al. Percutaneous laser ablation for benign and malignant thyroid diseases. Ultrasonography, 2019, 38(1): 25-36.
21. Lim HK, Lee JH, Ha EJ, et al. Radiofrequency ablation of benign non-functioning thyroid nodules: 4-year follow-up results for 111 patients. Eur Radiol, 2013, 23(4): 1044-1049.
22. Valcavi R, Riganti F, Bertani A, et al. Percutaneous laser ablation of cold benign thyroid nodules: a 3-year follow-up study in 122 patients. Thyroid, 2010, 20(11): 1253-1261.
23. 劉玉輝, 王文玲, 王毅, 等. 超聲引導下經皮微波消融甲狀腺術后復發結節的臨床研究. 臨床耳鼻咽喉頭頸外科雜志, 2015, 29(7): 622-624.
24. 閆磊, 章建全, 陳紅瓊, 等. 甲狀腺結節微波消融治療后6個月消融區細胞活性的酶組織化學檢測. 第二軍醫大學學報, 2019, 40(1): 20-24.
25. Rahal Junior A, Falsarella PM, Mendes GF, et al. Percutaneous laser ablation of benign thyroid nodules: a one year follow-up study. Einstein (Sao Paulo), 2018, 16(4): eAO4279.
26. 馬樹花, 周平. 超聲引導下熱消融治療甲狀腺結節的應用. 中外醫學研究, 2014, 12(13): 146-147, 148.
27. 郝少龍, 馬紀紅, 姜立新, 等. 熱消融術在甲狀腺結節微創治療中的應用進展. 中華普通外科學文獻: 電子版, 2016, 10(1): 77-80.
28. 章建全. 甲狀腺結節經皮射頻、微波消融治療指南. 中國醫刊, 2014, 49: 90-96.
29. Lee CU, Kim SJ, Sung JY, et al. Needle track tumor seeding after radiofrequency ablation of a thyroid tumor. Jpn J Radiol, 2014, 32(11): 661-663.
30. 張恒. 甲狀腺結節射頻消融治療的效果探析. 中國醫藥指南, 2015, 13(17): 279-280.
31. 李建如, 羅渝昆. 射頻消融技術在甲狀腺結節治療中的應用. 解放軍醫學院學報, 2016, 37(7): 807-809.
32. 紀莉, 吳鳳林, 婁雪峰, 等. 超聲彈性成像評估甲狀腺良性結節射頻消融效果的價值探討. 中國超聲醫學雜志, 2014, 30(12): 1071-1073.
33. 刁宗平, 章建全, 盛建國, 等. 超聲彈性成像在甲狀腺良性結節射頻消融中的應用價值及相關動態分析. 第二軍醫大學學報, 2017, 38(7): 947-950.
34. 孔月, 程志剛, 韓治宇, 等. 組織彈性定量分析在甲狀腺良性病灶微波消融治療中的應用價值. 中國超聲醫學雜志, 2014, 30(6): 489-492.
35. Huh JY, Baek JH, Choi H, et al. Symptomatic benign thyroid nodules: efficacy of additional radiofrequency ablation treatment session—prospective randomized study. Radiology, 2012, 263(3): 909-916.
36. 董文武, 張浩, 張平, 等. 甲狀腺乳頭狀癌射頻消融治療后再手術5例臨床分析. 中國實用外科雜志, 2015, 35(6): 653-655.
37. 楊映弘, 顏璟, 吳艷軍, 等. 液體隔離帶法與杠桿撬離法在超聲引導下甲狀腺微波消融術中的應用比較. 中國現代普通外科進展, 2018, 21(1): 28-30.
38. 章建全, 盛建國, 刁宗平, 等. 液體隔離法在頸部結節性病變經皮熱消融治療中的應用. 第二軍醫大學學報, 2014, 35(10): 1045-1052.
39. 孔月, 程志剛, 韓治宇, 等. 移動消融技術在微波消融治療甲狀腺良性結節中的應用價值. 解放軍醫學院學報, 2014, 35(7): 660-662, 691.
40. Ahn HS, Kim SJ, Park SH, et al. Radiofrequency ablation of benign thyroid nodules: evaluation of the treatment efficacy using ultrasonography. Ultrasonography, 2016, 35(3): 244-252.
41. 單海琳, 鄒大中, 邵清. 超聲造影評價甲狀腺結節激光消融療效的應用. 東南大學學報: 醫學版, 2016, 35(1): 36-40.
42. Yue W, Wang S, Wang B, et al. Ultrasound guided percutaneous microwave ablation of benign thyroid nodules: safety and imaging follow-up in 222 patients. Eur J Radiol, 2013, 82(1): e11-e16.
43. 曲明, 楊強, 尹惠生, 等. 超聲引導下甲狀腺結節微波消融術圍手術期處理. 實用醫藥雜志, 2016, 33(7): 599-602.

CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY

Research progress of residual nodules after thermal ablation for benign thyroid nodules

Abstract Full text Figures/Tables Video References Cited by

Previous Article

Next Article

Format

Content