- Affiliated Hospital of North Sichuan Medical College, Nanchong, 637000, Sichuan, P. R. China;
[Abstract]Postoperative lung cancer patients experience a significant symptom burden that severely impacts their quality of life. Accurate assessment of their health experience during recovery is critical to postoperative management. Patient-reported outcomes (PROs), which provide valuable insights into health from the patient's perspective, are increasingly used in the postoperative management of lung cancer patients. This article reviews the existing patient-reported outcome measures (PROMs) for lung cancer patients, focusing on their measurement dimensions, clinical applicability, and current usage. It aims to provide a foundation for their scientific application, optimize postoperative management strategies, and promote high-quality recovery and management.
Copyright ? the editorial department of Chinese Journal of Clinical Thoracic and Cardiovascular Surgery of West China Medical Publisher. All rights reserved
| 1. | 鄭榮壽, 張思維, 孫可欣, 等. 2016年中國惡性腫瘤流行情況分析. 中華腫瘤雜志, 2023, 45(3): 212-220.Zheng RS, Zhang SW, Sun KX, et al. Cancer statistics in China, 2016. Chin J Oncol, 2023, 45(3): 212-220. |
| 2. | 鄭榮壽, 陳茹, 韓冰峰, 等. 2022年中國惡性腫瘤流行情況分析. 中華腫瘤雜志, 2024, 46(3): 221-231.Zheng RS, Chen R, Han BF, et al. Cancer incidence and mortality in China, 2022. Chin J Oncol, 2024, 46(3): 221-231. |
| 3. | 張遜. 我國胸外科發展現狀分析. 中國肺癌雜志, 2014, 17(7): 518-522.Zhang X. Current status analysis of development of thoracic surgery in China. Chin J Lung Cancer, 2014, 17(7): 518-522. |
| 4. | 中華醫學會腫瘤學分會. 中華醫學會肺癌臨床診療指南 (2024版). 中華腫瘤雜志, 2024, 46(9): 805-843.Chinese Society of Clinical Oncology. Chinese Medical Association guideline for clinical diagnosis and treatment of lung cancer (2024 edition). Chin J Oncol, 2024, 46(9): 805-843. |
| 5. | 國家衛生健康委辦公廳. 原發性肺癌診療指南(2022年版). 協和醫學雜志, 2022, 13(4): 549-570.General Office of National Health Commission of the People's Republic of China. Clinical practice guideline for primary lung cancer (2022 version). Med J Peking Union Med Coll Hosp, 2022, 13(4): 549-570. |
| 6. | 高樹庚. 加速康復外科在肺癌圍術期管理中的應用. 山東大學學報(醫學版), 2022, 60(11): 1-10.Gao SG. Application of enhanced recovery after surgery in perioperative management of lung cancer. J Shandong Univ (Health Sci), 2022, 60(11): 1-10. |
| 7. | Ljungqvist O, Scott M, Fearon KC. Enhanced recovery after surgery: a review. JAMA Surg, 2017, 152(3): 292-298. |
| 8. | 馮銳, 馮競, 鄒宗望, 等. 快速康復外科在早期非小細胞肺癌微創手術中臨床應用. 中華腫瘤防治雜志, 2020, 27(8): 653-657.Feng R, Feng J, Zou ZW, et al. Application of FTS in minimally invasive surgery of early non-small cell lung cancer. Chin J Cancer Prev Treat, 2020, 27(8): 653-657. |
| 9. | Huang L, Frandsen MN, Kehlet H, et al. Early and late readmissions after enhanced recovery thoracoscopic lobectomy. Eur J Cardiothorac Surg, 2022, 62(3): ezac385. |
| 10. | 于海榮, 王曉莉, 陳宏林, 等. 快速康復模式下肺癌術后患者癥狀群的橫斷面研究. 現代臨床護理, 2020, 19(11): 13-18.Yu HR, Wang XL, Chen HL, et al. Postoperative symptomatic clusters in lung cancer patients under rapid recovery mode: a cross-sectional survey. Mod Clin Nurs, 2020, 19(11): 13-18. |
| 11. | 張歡歡, 張娜, 劉燕, 等. 肺癌患者圍手術期癥狀群的縱向調查研究. 中國胸心血管外科臨床雜志, 2025, 32(4): 508-514.Zhang HH, Zhang N, Liu Y, et al. Perioperative symptom clusters in patients with lung cancer: a longitudinal investigation. Chin J Clin Thorac Cardiovasc Surg, 2025, 32(4): 508-514. |
| 12. | 毛瑩穎, 丁君蓉, 胡穎燕, 等. 肺癌患者圍手術期癥狀群的研究進展. 中國護理管理, 2024, 24(6): 876-880.Mao YY, Ding JR, Hu YY, et al. Research progress on symptom clusters in patients with lung cancer in perioperative period. Chin Nurs Manag, 2024, 24(6): 876-880. |
| 13. | 姚麗, 鄭娥, 楊梅, 等. 基于患者報告結局的胸腔鏡肺癌切除術后患者癥狀調查. 中國胸心血管外科臨床雜志, 2023, 30(1): 84-88.Yao L, Zheng E, Yang M, et al. A survey of symptoms after thoracoscopic lung cancer resection based on patient-reported outcomes. Chin J Thorac Cardiovasc Surg, 2023, 30(1): 84-88. |
| 14. | Yang P, Cheville AL, Wampfler JA, et al. Quality of life and symptom burden among long-term lung cancer survivors. J Thorac Oncol, 2012, 7(1): 64-70. |
| 15. | 李京京, 呂曉晴, 劉杉杉, 等. 圍手術期肺癌患者癥狀群與生活質量相關性的縱向研究. 中華護理雜志, 2020, 55(11): 1635-1641.Li JJ, Lü XQ, Liu SS, et al. A longitudinal study on the correlations between symptom clusters and quality of life in patients with lung cancer during perioperation. Chin J Nurs, 2020, 55(11): 1635-1641. |
| 16. | 戴建娟, 王薇, 顏波兒, 等. 重返工作崗位肺癌患者工作生活質量現狀及影響因素分析. 中華全科醫學, 2024, 22(3): 513-516.Dai JJ, Wang W, Yan BE, et al. Quality of work and life and its influencing factors in lung cancer patients returning to work. Chin J Gen Pract, 2024, 22(3): 513-516. |
| 17. | 史釗, 竇蕾, 李順平. 國內外患者報告結局的應用現狀與研究進展. 中國全科醫學, 2023, 26(4): 401-408.Shi Z, Dou L, Li SP. Patient-reported outcome: recent advances in applications and research at home and abroad. Chin Gen Pract, 2023, 26(4): 401-408. |
| 18. | Basch E. The missing voice of patients in drug-safety reporting. N Engl J Med, 2010, 362(10): 865-869. |
| 19. | 張崎, 戴維, 魏星, 等. 患者報告結局量表在肺癌外科中的應用現狀. 中國胸心血管外科臨床雜志, 2024, 31(4): 606-612.Zhang Q, Dai W, Wei X, et al. Application status of patient-reported outcome scale in lung cancer surgery. Chin J Clin Thorac Cardiovasc Surg, 2024, 31(4): 606-612. |
| 20. | 關佳瑞, 張彭, 謝洋. 肺癌患者報告結局測評工具的研究近況與思考. 世界中醫藥, 2022, 17(17): 2490-2495.Guan JR, Zhang P, Xie Y. Status quo and consideration of patient-reported outcome measurements for lung cancer. World Chin Med, 2022, 17(17): 2490-2495. |
| 21. | 陳偉皓, 張孟尼, 沈誠. 患者報告結局和醫患共同決策在胸外科臨床中的應用. 中國肺癌雜志, 2024, 27(10): 792-798.Chen WH, Zhang MN, Shen C. Application of patient-reported outcomes and shared decision-making in thoracic surgery. Chin J Lung Cancer, 2024, 27(10): 792-798. |
| 22. | 戴維, 石丘玲, 李強, 等. 基于患者報告結局的癥狀管理在肺癌外科的應用現狀. 中國胸心血管外科臨床雜志, 2020, 27(10): 1228-1234.Dai W, Shi QL, Li Q, et al. Application status of patient-reported outcome–based symptom management in thoracic surgery for lung cancer. Chin J Clin Thorac Cardiovasc Surg, 2020, 27(10): 1228-1234. |
| 23. | 張桂英, 游月媛, 周小芹, 等. 肺癌隨機對照試驗中患者報告結局的質量評價及影響因素: 基于CONSORT-PRO擴展版. 中國胸心血管外科臨床雜志, 2025, 32(3): 322-331.Zhang GY, You YY, Zhou XQ, et al. Reporting quality and influencing factors of patient-reported outcomes in randomized controlled trials of lung cancer: based on the CONSORT-PRO extension. Chin J Clin Thorac Cardiovasc Surg, 2025, 32(3): 322-331. |
| 24. | Aaronson NK, Ahmedzai S, Bergman B, et al. The European Organization for Research and Treatment of Cancer QLQ-C30: a quality-of-life instrument for use in international clinical trials in oncology. J Natl Cancer Inst, 1993, 85(5): 365-376. |
| 25. | Fayers PM, Aaronson N, Bjordal K, et al. EORTC QLQ-C30 scoring manual: this manual is intended to assist users with scoring procedures for the QLQ-C30 version 3 and earlier, and the QLQ supplementary modules. 3rd ed. Brussels: EORTC, 2001. |
| 26. | de Rooij BH, van den Hurk C, Smaardijk V, et al. Development of an updated, standardized, patient-centered outcome set for lung cancer. Lung Cancer Amst Neth, 2022, 173: 5-13. |
| 27. | Mak KS, van Bommel ACM, Stowell C, et al. Defining a standard set of patient-centred outcomes for lung cancer. Eur Respir J, 2016, 48(3): 852-860. |
| 28. | El Alami Y, Essangri H, Majbar MA, et al. Psychometric validation of the Moroccan version of the EORTC QLQ-C30 in colorectal Cancer patients: cross-sectional study and systematic literature review. BMC Cancer, 2021, 21(1): 99. |
| 29. | Fredheim OMS, Borchgrevink PC, Saltnes T, et al. Validation and comparison of the health-related quality-of-life instruments EORTC QLQ-C30 and SF-36 in assessment of patients with chronic nonmalignant pain. J Pain Symptom Manage, 2007, 34(6): 657-665. |
| 30. | Mystakidou K, Tsilika E, Parpa E, et al. The EORTC core quality of life questionnaire (QLQ-C30, version 3. 0) in terminally ill cancer patients under palliative care: validity and reliability in a Hellenic sample. Int J Cancer, 2001, 94(1): 135-139. |
| 31. | Zhao H, Kanda K. Testing psychometric properties of the standard Chinese version of the European Organization for Research and Treatment of Cancer Quality of Life Core Questionnaire 30 (EORTC QLQ-C30). J Epidemiol, 2004, 14(6): 193-203. |
| 32. | Wan C, Meng Q, Yang Z, et al. Validation of the simplified Chinese version of EORTC QLQ-C30 from the measurements of five types of inpatients with cancer. Ann Oncol, 2008, 19(12): 2053-2060. |
| 33. | Zhang L, Su Y, Hua Y, et al. Validation of EORTC QLQ-LC43 for Chinese patients with lung cancer. Lung Cancer Amst Neth, 2014, 85(1): 94-98. |
| 34. | Sprangers MA, Cull A, Groenvold M, et al. The European Organization for Research and Treatment of Cancer approach to developing questionnaire modules: an update and overview. Qual Life Res Int J Qual Life Asp Treat Care Rehabil, 1998, 7(4): 291-300. |
| 35. | Koller M, Hjermstad MJ, Tomaszewski KA, et al. An international study to revise the EORTC questionnaire for assessing quality of life in lung cancer patients. Ann Oncol Off J Eur Soc Med Oncol, 2017, 28(11): 2874-2881. |
| 36. | Bergman B, Aaronson NK, Ahmedzai S, et al. The EORTC QLQ-LC13: a modular supplement to the EORTC Core Quality of Life Questionnaire (QLQ-C30) for use in lung cancer clinical trials. Eur J Cancer Oxf Engl 1990, 1994, 30A(5): 635-642. |
| 37. | Wang M, Herbst RS, Boshoff C. Toward personalized treatment approaches for non-small-cell lung cancer. Nat Med, 2021, 27(8): 1345-1356. |
| 38. | Koller M, Shamieh O, Hjermstad MJ, et al. Psychometric properties of the updated EORTC module for assessing quality of life in patients with lung cancer (QLQ-LC29): an international, observational field study. Lancet Oncol, 2020, 21(5): 723-732. |
| 39. | Dai W, Wang Y, Liu Y, et al. Translation and adaptation of the EORTC QLQ-LC 29 for use in Chinese patients with lung cancer. J Patient-Rep Outcomes, 2021, 5(1): 122. |
| 40. | 張崎. 肺癌患者單孔和多孔胸腔鏡術后生活質量的對比研究. 成都: 成都醫學院, 2023.Zhang Q. Comparative study on quality of life of patients with lung cancer after uniportal and multiportal thoracoscopic lobectomy [dissertation]. Chengdu: Chengdu Med Coll, 2023. |
| 41. | Schmid S, Becker H, Fritsch R, et al. Study protocol for a randomised controlled trial on pulmonary metastasectomy vs. standard of care in colorectal cancer patients with ≥ 3 lung metastases (PUCC-Trial). Front Oncol, 2022, 12: 913896. |
| 42. | Koch M, Gr?fenstein L, Karnosky J, et al. Psychosocial burden and quality of life of lung cancer patients: results of the EORTC QLQ-C30/QLQ-LC29 questionnaire and Hornheide screening instrument. Cancer Manag Res, 2021, 13: 6191-6197. |
| 43. | Hircock C, Wang AJ, Goonaratne E, et al. Comparing the EORTC QLQ-LC13, EORTC QLQ-LC29, and the FACT-L for assessment of quality of life in patients with lung cancer - an updated systematic review. Curr Opin Support Palliat Care, 2024, 18(4): 260-268. |
| 44. | Koch M, Rothammer T, Rasch F, et al. Gender differences in symptom burden, functional performance and global quality of life of lung cancer patients receiving inpatient versus outpatient treatment. Cancer Manag Res, 2023, 15: 175-183. |
| 45. | 張崎, 戴維, 魏星, 等. 單孔與多孔胸腔鏡肺葉切除術后3個月患者生活質量比較. 中國肺癌雜志, 2023, 26(11): 843-850.Zhang Q, Dai W, Wei X, et al. Comparison of quality of life of the patients three months after uniportal and multiportal thoracoscopic lobectomy. Chin J Lung Cancer, 2023, 26(11): 843-850. |
| 46. | 萬崇華, 孟瓊, 羅家洪, 等. 癌癥患者生命質量測定量表體系共性模塊的研制(一): 條目篩選及共性模塊的形成. 癌癥, 2007, 26(2): 113-117.Wan CH, Meng Q, Luo JH, et al. Development of the general module the system of quality of life instruments for cancer patients: item selection and structure of the general module. Chin J Cancer, 2007, 26(2): 113-117. |
| 47. | 萬崇華, 孟瓊, 楊錚, 等. 癌癥患者生命質量測定量表體系共性模塊的研制 (二): 信度與效度分析. 癌癥, 2007, 26(3): 225-229.Wan CH, Meng Q, Yang Z, et al. Development of the general module of the system of quality of life instruments for cancer patients: reliability and validity analysis. Chin J Cancer, 2007, 26(3): 225-229. |
| 48. | 萬崇華, 羅家洪, 楊錚, 等. 癌癥患者生命質量測定量表體系共性模塊的研制(三): 反應度分析. 癌癥, 2007, 26(4): 337-340.Wan CH, Luo JH, Yang Z, et al. Development of the general module of the system of quality of life instruments for cancer patients: responsiveness analysis. Chin J Cancer, 2007, 26(4): 337-340. |
| 49. | 萬崇華, 張燦珍, 李高峰, 等. 癌癥患者生命質量測定量表體系之肺癌量表QLICP-LU的研制與測量學特性評價. 中國腫瘤, 2007, 16(11): 858-861.Wan CH, Zhang CZ, Li GF, et al. Development and psychometric properties of the system of quality of life instruments for cancer patients: lung cancer QLICP-LU. China Cancer, 2007, 16(11): 858-861. |
| 50. | 趙夢迪. 癌癥患者生命質量測定量表體系之肺癌量表QLICP-LU(V2.0)的研制及其最小臨床重要性差值制定. 湛江: 廣東醫科大學, 2020.Zhao MD. Development of the lung cancer scale QLICP-LU(V2.0) among the system of quality of life instruments for cancer patients and estimations of its minimal clinically important difference [dissertation]. Zhanjiang: Guangdong Med Univ, 2020. |
| 51. | 楊錚. 癌癥患者生命質量測定量表共性模塊(V2.0)研制及最小臨床有意義差異制定. 廣州: 南方醫科大學, 2015.Yang Z. Development of the general module of the system of quality of life instruments for cancer patients (V2.0) and estimation of its minimal clinically important difference [dissertation]. Guangzhou: South Med Univ, 2015. |
| 52. | 萬崇華. 癌癥患者生命質量測定量表體系第2版QLICP(V2. 0)研究現狀. 廣東醫科大學學報, 2020, 38(5): 511-517.Wan CH. Research status on the second version of the system of quality of life instruments for cancer patients QLICP (V2. 0). J Guangdong Med Univ, 2020, 38(5): 511-517. |
| 53. | 李金河, 董斌, 文剛照. 胸腔鏡肺葉切除術、胸腔鏡肺段切除術對早期非小細胞肺癌的療效、肺功能及遠期生存質量分析. 中國全科醫學, 2019, 22(S2): 73-75.Li JH, Dong B, Wen GZ. Analysis of thoracoscopic lobectomy, thoracoscopic segmentectomy in the patients with early stage non-small cell lung cancer and its influence on the efficacy, lung function and long-term quality of life. Chin Gen Pract, 2019, 22(S2): 73-75. |
| 54. | 謝忠海, 沈琦斌, 李鴻偉, 等. 埃克替尼片聯合胸腔鏡微創治療非小細胞肺癌的臨床研究. 中國臨床藥理學雜志, 2017, 33(13): 1181-1183,1187.Xie ZH, Shen QB, Li HW, et al. Clinical trial of icotinib combined with thoracoscope minimally invasive in the treatment of non-small cell lung cancer. Chin J Clin Pharmacol, 2017, 33(13): 1181-1183,1187. |
| 55. | 林雙蘭, 周建榮, 趙良輝, 等. 肺癌患者常見癥狀群及與生存質量的相關性研究. 重慶醫科大學學報, 2013, 38(7): 683-686.Lin SL, Zhou JR, Zhao LH, et al. Symptom cluster and its relationship with life quality of patients with lung cancer. Chongqing Yike Daxue Xuebao, 2013, 38(7): 683-686. |
| 56. | Cella DF, Bonomi AE, Lloyd SR, et al. Reliability and validity of the Functional Assessment of Cancer Therapy-Lung (FACT-L) quality of life instrument. Lung Cancer Amst Neth, 1995, 12(3): 199-220. |
| 57. | Butt Z, Webster K, Eisenstein AR, et al. Quality of life in lung cancer: the validity and cross-cultural applicability of the Functional Assessment Of Cancer Therapy-Lung scale. Hematol Oncol Clin North Am, 2005, 19(2): 389-420,viii. |
| 58. | Cleeland CS, Mendoza TR, Wang XS, et al. Assessing symptom distress in cancer patients: the M. D. Anderson Symptom Inventory. Cancer, 2000, 89(7): 1634-1646. |
| 59. | MD Anderson Cancer Center. MD Anderson Symptom Inventory (MDASI). |
| 60. | Wang XS, Wang Y, Guo H, et al. Chinese version of the M. D. Anderson Symptom Inventory: validation and application of symptom measurement in cancer patients. Cancer, 2004, 101(8): 1890-1901. |
| 61. | Mendoza TR, Wang XS, Lu C, et al. Measuring the symptom burden of lung cancer: the validity and utility of the lung cancer module of the M. D. Anderson Symptom Inventory. The Oncologist, 2011, 16(2): 217-227. |
| 62. | 張立力, 臧瑜. MD安德森癥狀評估量表肺癌模塊的修訂和考評. 腫瘤, 2013, 33(5): 434-438.Zhang LL, Zang Y. Revision and evaluation of the lung cancer module of the MD Anderson Symptom Inventory. Zhong Liu, 2013, 33(5): 434-438. |
| 63. | 劉麗峰, 崔嘉, 王海楠, 等. 肺癌術后患者癥狀群對恐懼疾病進展的影響. 護理學雜志, 2024, 39(6): 37-41.Liu LF, Cui J, Wang HN, et al. Impact of symptom clusters on fear of disease progression in postoperative lung cancer patient. J Nurs Sci, 2024, 39(6): 37-41. |
| 64. | 王小波, 王慧虹, 侯禮佳, 等. 基于網絡分析肺癌圍術期核心癥狀的調查性研究. 護士進修雜志, 2023, 38(24): 2333-2339.Wang XB, Wang HH, Hou LJ, et al. An investigative study on perioperative core symptoms of lung cancer based on network analysis. J Nurses Train, 2023, 38(24): 2333-2339. |
| 65. | 殷秀敏, 高金萍, 彭英, 等. 肺癌術后患者同期癥狀網絡分析及核心癥狀識別. 護士進修雜志, 2023, 38(24): 2255-2261.Yin XM, Gao JP, Peng Y, et al. An investigative study on perioperative core symptoms of lung cancer based on network analysis. J Nurses Train, 2023, 38(24): 2255-2261. |
| 66. | 王明銘, 李霞, 車國衛, 等. 肺癌患者術后癥狀評估量表的有效性及臨床應用. 中國胸心血管外科臨床雜志, 2017, 24(6): 417-422.Wang MM, Li X, Che GW, et al. Effectiveness and clinical application of the postoperative symptom assessment scale for patients with lung cancer. Chin J Clin Thorac Cardiovasc Surg, 2017, 24(6): 417-422. |
| 67. | 周坤, 車國衛. 肺癌患者術后癥狀量表的建立和評價. 中國循證醫學雜志, 2020, 20(10): 1157-1163.Zhou K, Che GW. Establishment and evaluation of postoperative symptom inventory for patients with lung cancer. Chin J Evid Based Med, 2020, 20(10): 1157-1163. |
| 68. | 金寬哲, 黃燕飛, 吳小波. 吸入式異丙托溴銨治療非小細胞肺癌合并慢性阻塞性肺疾病患者的臨床研究. 中國臨床藥理學雜志, 2024, 40(6): 802-806.Jin KZ, Huang YF, Wu XB. Clinical trial of inhaled ipratropium bromide in the treatment of patients with non-small cell lung cancer combined with chronic obstructive pulmonary disease. Chin J Clin Pharmacol, 2024, 40(6): 802-806. |
| 69. | 劉桂先. 非小細胞肺癌術后癥狀及縱向變化的研究. 瀘州: 西南醫科大學, 2024.Liu GX. Stuty of postoperative symptoms and longitudinal changes in non-small cell lung cancer [dissertation]. Luzhou: Southwest Med Univ, 2024. |
| 70. | 王楊, 張淑敏, 王嫣紅, 等. 早期肺癌患者術后癥狀變化的縱向研究. 現代實用醫學, 2023, 35(8): 1093-1095.Wang Y, Zhang SM, Wang YH, et al. A longitudinal study on postoperative symptom changes in early-stage lung cancer patients. Mod Pract Med, 2023, 35(8): 1093-1095. |
| 71. | 楊雪, 左玲玲, 趙梓邑, 等. 肺癌患者術后飲食種類與方案對其住院舒適度和康復的影響. 中國肺癌雜志, 2024, 27(6): 415-420.Yang X, Zuo LL, Zhao ZY, et al. Influence of postoperative diet type and regimen on hospital comfort and rehabilitation of lung cancer patients. Chin J Lung Cancer, 2024, 27(6): 415-420. |
| 72. | 蘇雪娥, 方素珠, 何荷番, 等. 六字訣對快速康復外科非小細胞肺癌胸腔鏡肺葉切除術后病人肺癌術后癥狀及并發癥的影響. 全科護理, 2024, 22(15): 2883-2887.Su XE, Fang SZ, He HF, et al. Effect of the six-key procedure on postoperative symptoms and complications in fast-track thoracoscopic lobectomy for early-stage non-small cell lung cancer. Chin Gen Pract Nurs, 2024, 22(15): 2883-2887. |
| 73. | 28th annual conference of the International Society for Quality of Life Research. Qual Life Res Int J Qual Life Asp Treat Care Rehabil, 2021, 30(Suppl 1): 1-177. |
| 74. | U. S. Department of Health and Human Services FDA Center for Drug Evaluation and Research, U. S. Department of Health and Human Services FDA Center for Biologics Evaluation and Research, U. S. Department of Health and Human Services FDA Center for Devices and Radiological Health. Guidance for industry: patient-reported outcome measures: use in medical product development to support labeling claims: draft guidance. Health Qual Life Outcomes, 2006, 4: 79. |
| 75. | Su X, Huang Y, Gong R, et al. Undergoing lung surgery (PSA-Lung) was appropriate for symptom assessment after discharge. Qual Life Res, 2024, 33(7): 1807-1818. |
| 76. | Yang D, Hong Q, Zhao C, et al. Postoperative patient-reported outcomes after uniportal video-assisted thoracoscopic surgery using the perioperative symptom assessment for lung surgery scale. Curr Oncol Tor Ont, 2022, 29(10): 7645-7654. |
| 77. | 張開鑫. 多孔機器人和單孔胸腔鏡手術治療非小細胞肺癌的患者報告結局對比研究. 成都: 成都醫學院, 2024.Zhang KX. Comparative study of patient-reported outcomes after multiportal robotic-assisted thoracoscopic surgery and uniportal video-assisted thoracoscopic surgery for non-small cell lung cancer [dissertation]. Chengdu: Chengdu Med Coll, 2024. |
| 78. | 曹娟, 李方, 田雅麗, 等. 早期肺癌術后患者報告結局量表編制及信效度檢驗. 護理學雜志, 2023, 38(7): 35-39.Cao J, Li F, Tian Y, et al. Development and reliability and validity of the patient-reported outcomes scale after early lung cancer surgery. J Nurs Sci, 2023, 38(7): 35-39. |
| 79. | 劉云訪, 張桃, 高興蓮, 等. 肺癌患者術后居家癥狀報告結局及管理需求的混合研究. 護理學雜志, 2024, 39(8): 10-14.Liu Y, Zhang T, Gao X, et al. Patient reported outcomes of symptoms at home and symptom management needs after lung cancer surgery: a mixed-method study. J Nurs Sci, 2024, 39(8): 10-14. |
| 80. | 雷鋮. 基于患者報告結局的肺癌術后康復模塊化評估體系的構建及應用研究. 重慶: 重慶醫科大學, 2024.Lei L. Development of a modular postoperative rehabilitation assessment system for lung cancer based on PRO [dissertation]. Chongqing: Chongqing Med Univ, 2024. |
| 81. | Yu H, Lei C, Wei X, et al. Electronic symptom monitoring after lung cancer surgery: establishing a core set of patient-reported outcomes for surgical oncology care in a longitudinal cohort study. Int J Surg Lond Engl, 2024, 110(10): 6591-6600. |
| 82. | 黃麗華, 李東霞, 谷舉鳳, 等. 基于行為研究法的快速康復干預在早期非小細胞肺癌患者術后護理中的應用. 齊魯護理雜志, 2021, 27(18): 54-57.Huang LH, Li DX, Gu JF, et al. Application of behavioral research-based fast rehabilitation intervention in postoperative nursing of early non-small cell lung cancer patients. J Qilu Nurs, 2021, 27(18): 54-57. |
| 83. | Liu C, Liu T, Fang J, et al. Identifying symptom clusters and temporal interconnections in patients with lung tumors after CT-guided microwave ablation: a network analysis. Support Care Cancer, 2024, 32(6): 377. |
| 84. | Wang X, Gu D, Wei J, et al. Network evolution of core symptoms after lung cancer thoracoscopic surgery: a dynamic network analysis. Eur J Oncol Nurs, 2024, 70: 102546. |
| 85. | Dai W, Wang Y, Liao J, et al. Electronic patient-reported outcome-based symptom management versus usual care after lung cancer surgery: long-term results of a multicenter, randomized, controlled trial. J Clin Oncol, 2024, 42(18): 2126-2131. |
| 86. | Dai W, Feng W, Zhang Y, et al. Patient-reported outcome-based symptom management versus usual care after lung cancer surgery: a multicenter randomized controlled trial. J Clin Oncol, 2022, 40(9): 988-996. |
| 87. | Hassett MJ, Wong S, Osarogiagbon RU, et al. Implementation of patient-reported outcomes for symptom management in oncology practice through the SIMPRO research consortium: a protocol for a pragmatic type II hybrid effectiveness-implementation multi-center cluster-randomized stepped wedge trial. Trials, 2022, 23(1): 506. |
| 88. | National Cancer Policy Forum, Board on Health Care Services, Computer Science and Telecommunications Board, et al. Innovation in electronic health records for oncology care, research, and surveillance: proceedings of a workshop. Washington, D. C. : National Academies Press, 2023. |
| 89. | Generalova O, Roy M, Hall E, et al. Implementation of a cloud-based electronic patient-reported outcome (ePRO) platform in patients with advanced cancer. J Patient-Rep Outcomes, 2021, 5(1): 91. |
| 90. | Garcia Farina E, Rowell J, Revette A, et al. Barriers to electronic patient-reported outcome measurement among patients with cancer and limited English proficiency. JAMA Netw Open, 2022, 5(7): e2223898. |
| 91. | Tolstrup LK, Rasmussen IL, Pappot H. Insights from using patient-reported outcomes as an intervention during cancer treatment in Denmark: potential reasons for limited effectiveness. Health Qual Life Outcomes, 2025, 23(1): 85. |
| 92. | Cherny NI, Parrinello CM, Kwiatkowsky L, et al. Feasibility of large-scale implementation of an electronic patient-reported outcome remote monitoring system for patients on active treatment at a community cancer center. JCO Oncol Pract, 2022, 18(12): e1918-e1926. |
| 93. | Yamaguchi K, Higashiyama N, Umemiya M, et al. Electronic patient-reported outcomes as digital therapeutics for patients with cancer: a narrative review of current practices and future directions. Int J Clin Oncol, 2025, 30(1): 1-16. |
| 94. | 焦中禹, 李伊琤, 孫潤宸, 等. 心臟外科術后患者報告結局的臨床應用進展. 中國胸心血管外科臨床雜志, 2025: 1-7.Jiao ZY, Li YQ, Sun RC, et al. Clinical application progress of patient-reported outcomes in postoperative cardiac surgery patients. Chin J Thorac Cardiovasc Surg, 2025: 1-7. |
| 95. | Wójcik Z, Dimitrova V, Warrington L, et al. Using artificial intelligence to predict patient outcomes from patient-reported outcome measures: a scoping review. Health Qual Life Outcomes, 2025, 23(1): 37. |
| 96. | Krepper D, Cesari M, Hubel NJ, et al. Machine learning models including patient-reported outcome data in oncology: a systematic literature review and analysis of their reporting quality. J Patient-Rep Outcomes, 2024, 8(1): 126. |
| 97. | Asper N, Witschel HF, Von Stockar L, et al. Using machine learning approaches on dynamic patient-reported outcomes to cluster cancer treatment-related symptoms. Curr Oncol, 2025, 32(6): 334. |
| 98. | Balch JA, Chatham AH, Hong PKW, et al. Predicting patient reported outcome measures: a scoping review for the artificial intelligence-guided patient preference predictor. Front Artif Intell, 2024, 7: 1477447. |
| 99. | Zhou J, Muluneh B, Li Q, et al. Revolutionizing patient-reported outcomes analysis for oncology drug development using population models. Clin Cancer Res, 2025, 31(9): 1580-1586. |
| 100. | Aanes SG, Wiig S, Nieder C, et al. Implementing digital patient-reported outcomes in routine cancer care: barriers and facilitators. ESMO Real World Data Digit Oncol, 2024, 6: 100088. |
| 101. | Cruz Rivera S, Liu X, Hughes SE, et al. Embedding patient-reported outcomes at the heart of artificial intelligence health-care technologies. Lancet Digit Health, 2023, 5(3): e168-e173. |
- 1. 鄭榮壽, 張思維, 孫可欣, 等. 2016年中國惡性腫瘤流行情況分析. 中華腫瘤雜志, 2023, 45(3): 212-220.Zheng RS, Zhang SW, Sun KX, et al. Cancer statistics in China, 2016. Chin J Oncol, 2023, 45(3): 212-220.
- 2. 鄭榮壽, 陳茹, 韓冰峰, 等. 2022年中國惡性腫瘤流行情況分析. 中華腫瘤雜志, 2024, 46(3): 221-231.Zheng RS, Chen R, Han BF, et al. Cancer incidence and mortality in China, 2022. Chin J Oncol, 2024, 46(3): 221-231.
- 3. 張遜. 我國胸外科發展現狀分析. 中國肺癌雜志, 2014, 17(7): 518-522.Zhang X. Current status analysis of development of thoracic surgery in China. Chin J Lung Cancer, 2014, 17(7): 518-522.
- 4. 中華醫學會腫瘤學分會. 中華醫學會肺癌臨床診療指南 (2024版). 中華腫瘤雜志, 2024, 46(9): 805-843.Chinese Society of Clinical Oncology. Chinese Medical Association guideline for clinical diagnosis and treatment of lung cancer (2024 edition). Chin J Oncol, 2024, 46(9): 805-843.
- 5. 國家衛生健康委辦公廳. 原發性肺癌診療指南(2022年版). 協和醫學雜志, 2022, 13(4): 549-570.General Office of National Health Commission of the People's Republic of China. Clinical practice guideline for primary lung cancer (2022 version). Med J Peking Union Med Coll Hosp, 2022, 13(4): 549-570.
- 6. 高樹庚. 加速康復外科在肺癌圍術期管理中的應用. 山東大學學報(醫學版), 2022, 60(11): 1-10.Gao SG. Application of enhanced recovery after surgery in perioperative management of lung cancer. J Shandong Univ (Health Sci), 2022, 60(11): 1-10.
- 7. Ljungqvist O, Scott M, Fearon KC. Enhanced recovery after surgery: a review. JAMA Surg, 2017, 152(3): 292-298.
- 8. 馮銳, 馮競, 鄒宗望, 等. 快速康復外科在早期非小細胞肺癌微創手術中臨床應用. 中華腫瘤防治雜志, 2020, 27(8): 653-657.Feng R, Feng J, Zou ZW, et al. Application of FTS in minimally invasive surgery of early non-small cell lung cancer. Chin J Cancer Prev Treat, 2020, 27(8): 653-657.
- 9. Huang L, Frandsen MN, Kehlet H, et al. Early and late readmissions after enhanced recovery thoracoscopic lobectomy. Eur J Cardiothorac Surg, 2022, 62(3): ezac385.
- 10. 于海榮, 王曉莉, 陳宏林, 等. 快速康復模式下肺癌術后患者癥狀群的橫斷面研究. 現代臨床護理, 2020, 19(11): 13-18.Yu HR, Wang XL, Chen HL, et al. Postoperative symptomatic clusters in lung cancer patients under rapid recovery mode: a cross-sectional survey. Mod Clin Nurs, 2020, 19(11): 13-18.
- 11. 張歡歡, 張娜, 劉燕, 等. 肺癌患者圍手術期癥狀群的縱向調查研究. 中國胸心血管外科臨床雜志, 2025, 32(4): 508-514.Zhang HH, Zhang N, Liu Y, et al. Perioperative symptom clusters in patients with lung cancer: a longitudinal investigation. Chin J Clin Thorac Cardiovasc Surg, 2025, 32(4): 508-514.
- 12. 毛瑩穎, 丁君蓉, 胡穎燕, 等. 肺癌患者圍手術期癥狀群的研究進展. 中國護理管理, 2024, 24(6): 876-880.Mao YY, Ding JR, Hu YY, et al. Research progress on symptom clusters in patients with lung cancer in perioperative period. Chin Nurs Manag, 2024, 24(6): 876-880.
- 13. 姚麗, 鄭娥, 楊梅, 等. 基于患者報告結局的胸腔鏡肺癌切除術后患者癥狀調查. 中國胸心血管外科臨床雜志, 2023, 30(1): 84-88.Yao L, Zheng E, Yang M, et al. A survey of symptoms after thoracoscopic lung cancer resection based on patient-reported outcomes. Chin J Thorac Cardiovasc Surg, 2023, 30(1): 84-88.
- 14. Yang P, Cheville AL, Wampfler JA, et al. Quality of life and symptom burden among long-term lung cancer survivors. J Thorac Oncol, 2012, 7(1): 64-70.
- 15. 李京京, 呂曉晴, 劉杉杉, 等. 圍手術期肺癌患者癥狀群與生活質量相關性的縱向研究. 中華護理雜志, 2020, 55(11): 1635-1641.Li JJ, Lü XQ, Liu SS, et al. A longitudinal study on the correlations between symptom clusters and quality of life in patients with lung cancer during perioperation. Chin J Nurs, 2020, 55(11): 1635-1641.
- 16. 戴建娟, 王薇, 顏波兒, 等. 重返工作崗位肺癌患者工作生活質量現狀及影響因素分析. 中華全科醫學, 2024, 22(3): 513-516.Dai JJ, Wang W, Yan BE, et al. Quality of work and life and its influencing factors in lung cancer patients returning to work. Chin J Gen Pract, 2024, 22(3): 513-516.
- 17. 史釗, 竇蕾, 李順平. 國內外患者報告結局的應用現狀與研究進展. 中國全科醫學, 2023, 26(4): 401-408.Shi Z, Dou L, Li SP. Patient-reported outcome: recent advances in applications and research at home and abroad. Chin Gen Pract, 2023, 26(4): 401-408.
- 18. Basch E. The missing voice of patients in drug-safety reporting. N Engl J Med, 2010, 362(10): 865-869.
- 19. 張崎, 戴維, 魏星, 等. 患者報告結局量表在肺癌外科中的應用現狀. 中國胸心血管外科臨床雜志, 2024, 31(4): 606-612.Zhang Q, Dai W, Wei X, et al. Application status of patient-reported outcome scale in lung cancer surgery. Chin J Clin Thorac Cardiovasc Surg, 2024, 31(4): 606-612.
- 20. 關佳瑞, 張彭, 謝洋. 肺癌患者報告結局測評工具的研究近況與思考. 世界中醫藥, 2022, 17(17): 2490-2495.Guan JR, Zhang P, Xie Y. Status quo and consideration of patient-reported outcome measurements for lung cancer. World Chin Med, 2022, 17(17): 2490-2495.
- 21. 陳偉皓, 張孟尼, 沈誠. 患者報告結局和醫患共同決策在胸外科臨床中的應用. 中國肺癌雜志, 2024, 27(10): 792-798.Chen WH, Zhang MN, Shen C. Application of patient-reported outcomes and shared decision-making in thoracic surgery. Chin J Lung Cancer, 2024, 27(10): 792-798.
- 22. 戴維, 石丘玲, 李強, 等. 基于患者報告結局的癥狀管理在肺癌外科的應用現狀. 中國胸心血管外科臨床雜志, 2020, 27(10): 1228-1234.Dai W, Shi QL, Li Q, et al. Application status of patient-reported outcome–based symptom management in thoracic surgery for lung cancer. Chin J Clin Thorac Cardiovasc Surg, 2020, 27(10): 1228-1234.
- 23. 張桂英, 游月媛, 周小芹, 等. 肺癌隨機對照試驗中患者報告結局的質量評價及影響因素: 基于CONSORT-PRO擴展版. 中國胸心血管外科臨床雜志, 2025, 32(3): 322-331.Zhang GY, You YY, Zhou XQ, et al. Reporting quality and influencing factors of patient-reported outcomes in randomized controlled trials of lung cancer: based on the CONSORT-PRO extension. Chin J Clin Thorac Cardiovasc Surg, 2025, 32(3): 322-331.
- 24. Aaronson NK, Ahmedzai S, Bergman B, et al. The European Organization for Research and Treatment of Cancer QLQ-C30: a quality-of-life instrument for use in international clinical trials in oncology. J Natl Cancer Inst, 1993, 85(5): 365-376.
- 25. Fayers PM, Aaronson N, Bjordal K, et al. EORTC QLQ-C30 scoring manual: this manual is intended to assist users with scoring procedures for the QLQ-C30 version 3 and earlier, and the QLQ supplementary modules. 3rd ed. Brussels: EORTC, 2001.
- 26. de Rooij BH, van den Hurk C, Smaardijk V, et al. Development of an updated, standardized, patient-centered outcome set for lung cancer. Lung Cancer Amst Neth, 2022, 173: 5-13.
- 27. Mak KS, van Bommel ACM, Stowell C, et al. Defining a standard set of patient-centred outcomes for lung cancer. Eur Respir J, 2016, 48(3): 852-860.
- 28. El Alami Y, Essangri H, Majbar MA, et al. Psychometric validation of the Moroccan version of the EORTC QLQ-C30 in colorectal Cancer patients: cross-sectional study and systematic literature review. BMC Cancer, 2021, 21(1): 99.
- 29. Fredheim OMS, Borchgrevink PC, Saltnes T, et al. Validation and comparison of the health-related quality-of-life instruments EORTC QLQ-C30 and SF-36 in assessment of patients with chronic nonmalignant pain. J Pain Symptom Manage, 2007, 34(6): 657-665.
- 30. Mystakidou K, Tsilika E, Parpa E, et al. The EORTC core quality of life questionnaire (QLQ-C30, version 3. 0) in terminally ill cancer patients under palliative care: validity and reliability in a Hellenic sample. Int J Cancer, 2001, 94(1): 135-139.
- 31. Zhao H, Kanda K. Testing psychometric properties of the standard Chinese version of the European Organization for Research and Treatment of Cancer Quality of Life Core Questionnaire 30 (EORTC QLQ-C30). J Epidemiol, 2004, 14(6): 193-203.
- 32. Wan C, Meng Q, Yang Z, et al. Validation of the simplified Chinese version of EORTC QLQ-C30 from the measurements of five types of inpatients with cancer. Ann Oncol, 2008, 19(12): 2053-2060.
- 33. Zhang L, Su Y, Hua Y, et al. Validation of EORTC QLQ-LC43 for Chinese patients with lung cancer. Lung Cancer Amst Neth, 2014, 85(1): 94-98.
- 34. Sprangers MA, Cull A, Groenvold M, et al. The European Organization for Research and Treatment of Cancer approach to developing questionnaire modules: an update and overview. Qual Life Res Int J Qual Life Asp Treat Care Rehabil, 1998, 7(4): 291-300.
- 35. Koller M, Hjermstad MJ, Tomaszewski KA, et al. An international study to revise the EORTC questionnaire for assessing quality of life in lung cancer patients. Ann Oncol Off J Eur Soc Med Oncol, 2017, 28(11): 2874-2881.
- 36. Bergman B, Aaronson NK, Ahmedzai S, et al. The EORTC QLQ-LC13: a modular supplement to the EORTC Core Quality of Life Questionnaire (QLQ-C30) for use in lung cancer clinical trials. Eur J Cancer Oxf Engl 1990, 1994, 30A(5): 635-642.
- 37. Wang M, Herbst RS, Boshoff C. Toward personalized treatment approaches for non-small-cell lung cancer. Nat Med, 2021, 27(8): 1345-1356.
- 38. Koller M, Shamieh O, Hjermstad MJ, et al. Psychometric properties of the updated EORTC module for assessing quality of life in patients with lung cancer (QLQ-LC29): an international, observational field study. Lancet Oncol, 2020, 21(5): 723-732.
- 39. Dai W, Wang Y, Liu Y, et al. Translation and adaptation of the EORTC QLQ-LC 29 for use in Chinese patients with lung cancer. J Patient-Rep Outcomes, 2021, 5(1): 122.
- 40. 張崎. 肺癌患者單孔和多孔胸腔鏡術后生活質量的對比研究. 成都: 成都醫學院, 2023.Zhang Q. Comparative study on quality of life of patients with lung cancer after uniportal and multiportal thoracoscopic lobectomy [dissertation]. Chengdu: Chengdu Med Coll, 2023.
- 41. Schmid S, Becker H, Fritsch R, et al. Study protocol for a randomised controlled trial on pulmonary metastasectomy vs. standard of care in colorectal cancer patients with ≥ 3 lung metastases (PUCC-Trial). Front Oncol, 2022, 12: 913896.
- 42. Koch M, Gr?fenstein L, Karnosky J, et al. Psychosocial burden and quality of life of lung cancer patients: results of the EORTC QLQ-C30/QLQ-LC29 questionnaire and Hornheide screening instrument. Cancer Manag Res, 2021, 13: 6191-6197.
- 43. Hircock C, Wang AJ, Goonaratne E, et al. Comparing the EORTC QLQ-LC13, EORTC QLQ-LC29, and the FACT-L for assessment of quality of life in patients with lung cancer - an updated systematic review. Curr Opin Support Palliat Care, 2024, 18(4): 260-268.
- 44. Koch M, Rothammer T, Rasch F, et al. Gender differences in symptom burden, functional performance and global quality of life of lung cancer patients receiving inpatient versus outpatient treatment. Cancer Manag Res, 2023, 15: 175-183.
- 45. 張崎, 戴維, 魏星, 等. 單孔與多孔胸腔鏡肺葉切除術后3個月患者生活質量比較. 中國肺癌雜志, 2023, 26(11): 843-850.Zhang Q, Dai W, Wei X, et al. Comparison of quality of life of the patients three months after uniportal and multiportal thoracoscopic lobectomy. Chin J Lung Cancer, 2023, 26(11): 843-850.
- 46. 萬崇華, 孟瓊, 羅家洪, 等. 癌癥患者生命質量測定量表體系共性模塊的研制(一): 條目篩選及共性模塊的形成. 癌癥, 2007, 26(2): 113-117.Wan CH, Meng Q, Luo JH, et al. Development of the general module the system of quality of life instruments for cancer patients: item selection and structure of the general module. Chin J Cancer, 2007, 26(2): 113-117.
- 47. 萬崇華, 孟瓊, 楊錚, 等. 癌癥患者生命質量測定量表體系共性模塊的研制 (二): 信度與效度分析. 癌癥, 2007, 26(3): 225-229.Wan CH, Meng Q, Yang Z, et al. Development of the general module of the system of quality of life instruments for cancer patients: reliability and validity analysis. Chin J Cancer, 2007, 26(3): 225-229.
- 48. 萬崇華, 羅家洪, 楊錚, 等. 癌癥患者生命質量測定量表體系共性模塊的研制(三): 反應度分析. 癌癥, 2007, 26(4): 337-340.Wan CH, Luo JH, Yang Z, et al. Development of the general module of the system of quality of life instruments for cancer patients: responsiveness analysis. Chin J Cancer, 2007, 26(4): 337-340.
- 49. 萬崇華, 張燦珍, 李高峰, 等. 癌癥患者生命質量測定量表體系之肺癌量表QLICP-LU的研制與測量學特性評價. 中國腫瘤, 2007, 16(11): 858-861.Wan CH, Zhang CZ, Li GF, et al. Development and psychometric properties of the system of quality of life instruments for cancer patients: lung cancer QLICP-LU. China Cancer, 2007, 16(11): 858-861.
- 50. 趙夢迪. 癌癥患者生命質量測定量表體系之肺癌量表QLICP-LU(V2.0)的研制及其最小臨床重要性差值制定. 湛江: 廣東醫科大學, 2020.Zhao MD. Development of the lung cancer scale QLICP-LU(V2.0) among the system of quality of life instruments for cancer patients and estimations of its minimal clinically important difference [dissertation]. Zhanjiang: Guangdong Med Univ, 2020.
- 51. 楊錚. 癌癥患者生命質量測定量表共性模塊(V2.0)研制及最小臨床有意義差異制定. 廣州: 南方醫科大學, 2015.Yang Z. Development of the general module of the system of quality of life instruments for cancer patients (V2.0) and estimation of its minimal clinically important difference [dissertation]. Guangzhou: South Med Univ, 2015.
- 52. 萬崇華. 癌癥患者生命質量測定量表體系第2版QLICP(V2. 0)研究現狀. 廣東醫科大學學報, 2020, 38(5): 511-517.Wan CH. Research status on the second version of the system of quality of life instruments for cancer patients QLICP (V2. 0). J Guangdong Med Univ, 2020, 38(5): 511-517.
- 53. 李金河, 董斌, 文剛照. 胸腔鏡肺葉切除術、胸腔鏡肺段切除術對早期非小細胞肺癌的療效、肺功能及遠期生存質量分析. 中國全科醫學, 2019, 22(S2): 73-75.Li JH, Dong B, Wen GZ. Analysis of thoracoscopic lobectomy, thoracoscopic segmentectomy in the patients with early stage non-small cell lung cancer and its influence on the efficacy, lung function and long-term quality of life. Chin Gen Pract, 2019, 22(S2): 73-75.
- 54. 謝忠海, 沈琦斌, 李鴻偉, 等. 埃克替尼片聯合胸腔鏡微創治療非小細胞肺癌的臨床研究. 中國臨床藥理學雜志, 2017, 33(13): 1181-1183,1187.Xie ZH, Shen QB, Li HW, et al. Clinical trial of icotinib combined with thoracoscope minimally invasive in the treatment of non-small cell lung cancer. Chin J Clin Pharmacol, 2017, 33(13): 1181-1183,1187.
- 55. 林雙蘭, 周建榮, 趙良輝, 等. 肺癌患者常見癥狀群及與生存質量的相關性研究. 重慶醫科大學學報, 2013, 38(7): 683-686.Lin SL, Zhou JR, Zhao LH, et al. Symptom cluster and its relationship with life quality of patients with lung cancer. Chongqing Yike Daxue Xuebao, 2013, 38(7): 683-686.
- 56. Cella DF, Bonomi AE, Lloyd SR, et al. Reliability and validity of the Functional Assessment of Cancer Therapy-Lung (FACT-L) quality of life instrument. Lung Cancer Amst Neth, 1995, 12(3): 199-220.
- 57. Butt Z, Webster K, Eisenstein AR, et al. Quality of life in lung cancer: the validity and cross-cultural applicability of the Functional Assessment Of Cancer Therapy-Lung scale. Hematol Oncol Clin North Am, 2005, 19(2): 389-420,viii.
- 58. Cleeland CS, Mendoza TR, Wang XS, et al. Assessing symptom distress in cancer patients: the M. D. Anderson Symptom Inventory. Cancer, 2000, 89(7): 1634-1646.
- 59. MD Anderson Cancer Center. MD Anderson Symptom Inventory (MDASI).
- 60. Wang XS, Wang Y, Guo H, et al. Chinese version of the M. D. Anderson Symptom Inventory: validation and application of symptom measurement in cancer patients. Cancer, 2004, 101(8): 1890-1901.
- 61. Mendoza TR, Wang XS, Lu C, et al. Measuring the symptom burden of lung cancer: the validity and utility of the lung cancer module of the M. D. Anderson Symptom Inventory. The Oncologist, 2011, 16(2): 217-227.
- 62. 張立力, 臧瑜. MD安德森癥狀評估量表肺癌模塊的修訂和考評. 腫瘤, 2013, 33(5): 434-438.Zhang LL, Zang Y. Revision and evaluation of the lung cancer module of the MD Anderson Symptom Inventory. Zhong Liu, 2013, 33(5): 434-438.
- 63. 劉麗峰, 崔嘉, 王海楠, 等. 肺癌術后患者癥狀群對恐懼疾病進展的影響. 護理學雜志, 2024, 39(6): 37-41.Liu LF, Cui J, Wang HN, et al. Impact of symptom clusters on fear of disease progression in postoperative lung cancer patient. J Nurs Sci, 2024, 39(6): 37-41.
- 64. 王小波, 王慧虹, 侯禮佳, 等. 基于網絡分析肺癌圍術期核心癥狀的調查性研究. 護士進修雜志, 2023, 38(24): 2333-2339.Wang XB, Wang HH, Hou LJ, et al. An investigative study on perioperative core symptoms of lung cancer based on network analysis. J Nurses Train, 2023, 38(24): 2333-2339.
- 65. 殷秀敏, 高金萍, 彭英, 等. 肺癌術后患者同期癥狀網絡分析及核心癥狀識別. 護士進修雜志, 2023, 38(24): 2255-2261.Yin XM, Gao JP, Peng Y, et al. An investigative study on perioperative core symptoms of lung cancer based on network analysis. J Nurses Train, 2023, 38(24): 2255-2261.
- 66. 王明銘, 李霞, 車國衛, 等. 肺癌患者術后癥狀評估量表的有效性及臨床應用. 中國胸心血管外科臨床雜志, 2017, 24(6): 417-422.Wang MM, Li X, Che GW, et al. Effectiveness and clinical application of the postoperative symptom assessment scale for patients with lung cancer. Chin J Clin Thorac Cardiovasc Surg, 2017, 24(6): 417-422.
- 67. 周坤, 車國衛. 肺癌患者術后癥狀量表的建立和評價. 中國循證醫學雜志, 2020, 20(10): 1157-1163.Zhou K, Che GW. Establishment and evaluation of postoperative symptom inventory for patients with lung cancer. Chin J Evid Based Med, 2020, 20(10): 1157-1163.
- 68. 金寬哲, 黃燕飛, 吳小波. 吸入式異丙托溴銨治療非小細胞肺癌合并慢性阻塞性肺疾病患者的臨床研究. 中國臨床藥理學雜志, 2024, 40(6): 802-806.Jin KZ, Huang YF, Wu XB. Clinical trial of inhaled ipratropium bromide in the treatment of patients with non-small cell lung cancer combined with chronic obstructive pulmonary disease. Chin J Clin Pharmacol, 2024, 40(6): 802-806.
- 69. 劉桂先. 非小細胞肺癌術后癥狀及縱向變化的研究. 瀘州: 西南醫科大學, 2024.Liu GX. Stuty of postoperative symptoms and longitudinal changes in non-small cell lung cancer [dissertation]. Luzhou: Southwest Med Univ, 2024.
- 70. 王楊, 張淑敏, 王嫣紅, 等. 早期肺癌患者術后癥狀變化的縱向研究. 現代實用醫學, 2023, 35(8): 1093-1095.Wang Y, Zhang SM, Wang YH, et al. A longitudinal study on postoperative symptom changes in early-stage lung cancer patients. Mod Pract Med, 2023, 35(8): 1093-1095.
- 71. 楊雪, 左玲玲, 趙梓邑, 等. 肺癌患者術后飲食種類與方案對其住院舒適度和康復的影響. 中國肺癌雜志, 2024, 27(6): 415-420.Yang X, Zuo LL, Zhao ZY, et al. Influence of postoperative diet type and regimen on hospital comfort and rehabilitation of lung cancer patients. Chin J Lung Cancer, 2024, 27(6): 415-420.
- 72. 蘇雪娥, 方素珠, 何荷番, 等. 六字訣對快速康復外科非小細胞肺癌胸腔鏡肺葉切除術后病人肺癌術后癥狀及并發癥的影響. 全科護理, 2024, 22(15): 2883-2887.Su XE, Fang SZ, He HF, et al. Effect of the six-key procedure on postoperative symptoms and complications in fast-track thoracoscopic lobectomy for early-stage non-small cell lung cancer. Chin Gen Pract Nurs, 2024, 22(15): 2883-2887.
- 73. 28th annual conference of the International Society for Quality of Life Research. Qual Life Res Int J Qual Life Asp Treat Care Rehabil, 2021, 30(Suppl 1): 1-177.
- 74. U. S. Department of Health and Human Services FDA Center for Drug Evaluation and Research, U. S. Department of Health and Human Services FDA Center for Biologics Evaluation and Research, U. S. Department of Health and Human Services FDA Center for Devices and Radiological Health. Guidance for industry: patient-reported outcome measures: use in medical product development to support labeling claims: draft guidance. Health Qual Life Outcomes, 2006, 4: 79.
- 75. Su X, Huang Y, Gong R, et al. Undergoing lung surgery (PSA-Lung) was appropriate for symptom assessment after discharge. Qual Life Res, 2024, 33(7): 1807-1818.
- 76. Yang D, Hong Q, Zhao C, et al. Postoperative patient-reported outcomes after uniportal video-assisted thoracoscopic surgery using the perioperative symptom assessment for lung surgery scale. Curr Oncol Tor Ont, 2022, 29(10): 7645-7654.
- 77. 張開鑫. 多孔機器人和單孔胸腔鏡手術治療非小細胞肺癌的患者報告結局對比研究. 成都: 成都醫學院, 2024.Zhang KX. Comparative study of patient-reported outcomes after multiportal robotic-assisted thoracoscopic surgery and uniportal video-assisted thoracoscopic surgery for non-small cell lung cancer [dissertation]. Chengdu: Chengdu Med Coll, 2024.
- 78. 曹娟, 李方, 田雅麗, 等. 早期肺癌術后患者報告結局量表編制及信效度檢驗. 護理學雜志, 2023, 38(7): 35-39.Cao J, Li F, Tian Y, et al. Development and reliability and validity of the patient-reported outcomes scale after early lung cancer surgery. J Nurs Sci, 2023, 38(7): 35-39.
- 79. 劉云訪, 張桃, 高興蓮, 等. 肺癌患者術后居家癥狀報告結局及管理需求的混合研究. 護理學雜志, 2024, 39(8): 10-14.Liu Y, Zhang T, Gao X, et al. Patient reported outcomes of symptoms at home and symptom management needs after lung cancer surgery: a mixed-method study. J Nurs Sci, 2024, 39(8): 10-14.
- 80. 雷鋮. 基于患者報告結局的肺癌術后康復模塊化評估體系的構建及應用研究. 重慶: 重慶醫科大學, 2024.Lei L. Development of a modular postoperative rehabilitation assessment system for lung cancer based on PRO [dissertation]. Chongqing: Chongqing Med Univ, 2024.
- 81. Yu H, Lei C, Wei X, et al. Electronic symptom monitoring after lung cancer surgery: establishing a core set of patient-reported outcomes for surgical oncology care in a longitudinal cohort study. Int J Surg Lond Engl, 2024, 110(10): 6591-6600.
- 82. 黃麗華, 李東霞, 谷舉鳳, 等. 基于行為研究法的快速康復干預在早期非小細胞肺癌患者術后護理中的應用. 齊魯護理雜志, 2021, 27(18): 54-57.Huang LH, Li DX, Gu JF, et al. Application of behavioral research-based fast rehabilitation intervention in postoperative nursing of early non-small cell lung cancer patients. J Qilu Nurs, 2021, 27(18): 54-57.
- 83. Liu C, Liu T, Fang J, et al. Identifying symptom clusters and temporal interconnections in patients with lung tumors after CT-guided microwave ablation: a network analysis. Support Care Cancer, 2024, 32(6): 377.
- 84. Wang X, Gu D, Wei J, et al. Network evolution of core symptoms after lung cancer thoracoscopic surgery: a dynamic network analysis. Eur J Oncol Nurs, 2024, 70: 102546.
- 85. Dai W, Wang Y, Liao J, et al. Electronic patient-reported outcome-based symptom management versus usual care after lung cancer surgery: long-term results of a multicenter, randomized, controlled trial. J Clin Oncol, 2024, 42(18): 2126-2131.
- 86. Dai W, Feng W, Zhang Y, et al. Patient-reported outcome-based symptom management versus usual care after lung cancer surgery: a multicenter randomized controlled trial. J Clin Oncol, 2022, 40(9): 988-996.
- 87. Hassett MJ, Wong S, Osarogiagbon RU, et al. Implementation of patient-reported outcomes for symptom management in oncology practice through the SIMPRO research consortium: a protocol for a pragmatic type II hybrid effectiveness-implementation multi-center cluster-randomized stepped wedge trial. Trials, 2022, 23(1): 506.
- 88. National Cancer Policy Forum, Board on Health Care Services, Computer Science and Telecommunications Board, et al. Innovation in electronic health records for oncology care, research, and surveillance: proceedings of a workshop. Washington, D. C. : National Academies Press, 2023.
- 89. Generalova O, Roy M, Hall E, et al. Implementation of a cloud-based electronic patient-reported outcome (ePRO) platform in patients with advanced cancer. J Patient-Rep Outcomes, 2021, 5(1): 91.
- 90. Garcia Farina E, Rowell J, Revette A, et al. Barriers to electronic patient-reported outcome measurement among patients with cancer and limited English proficiency. JAMA Netw Open, 2022, 5(7): e2223898.
- 91. Tolstrup LK, Rasmussen IL, Pappot H. Insights from using patient-reported outcomes as an intervention during cancer treatment in Denmark: potential reasons for limited effectiveness. Health Qual Life Outcomes, 2025, 23(1): 85.
- 92. Cherny NI, Parrinello CM, Kwiatkowsky L, et al. Feasibility of large-scale implementation of an electronic patient-reported outcome remote monitoring system for patients on active treatment at a community cancer center. JCO Oncol Pract, 2022, 18(12): e1918-e1926.
- 93. Yamaguchi K, Higashiyama N, Umemiya M, et al. Electronic patient-reported outcomes as digital therapeutics for patients with cancer: a narrative review of current practices and future directions. Int J Clin Oncol, 2025, 30(1): 1-16.
- 94. 焦中禹, 李伊琤, 孫潤宸, 等. 心臟外科術后患者報告結局的臨床應用進展. 中國胸心血管外科臨床雜志, 2025: 1-7.Jiao ZY, Li YQ, Sun RC, et al. Clinical application progress of patient-reported outcomes in postoperative cardiac surgery patients. Chin J Thorac Cardiovasc Surg, 2025: 1-7.
- 95. Wójcik Z, Dimitrova V, Warrington L, et al. Using artificial intelligence to predict patient outcomes from patient-reported outcome measures: a scoping review. Health Qual Life Outcomes, 2025, 23(1): 37.
- 96. Krepper D, Cesari M, Hubel NJ, et al. Machine learning models including patient-reported outcome data in oncology: a systematic literature review and analysis of their reporting quality. J Patient-Rep Outcomes, 2024, 8(1): 126.
- 97. Asper N, Witschel HF, Von Stockar L, et al. Using machine learning approaches on dynamic patient-reported outcomes to cluster cancer treatment-related symptoms. Curr Oncol, 2025, 32(6): 334.
- 98. Balch JA, Chatham AH, Hong PKW, et al. Predicting patient reported outcome measures: a scoping review for the artificial intelligence-guided patient preference predictor. Front Artif Intell, 2024, 7: 1477447.
- 99. Zhou J, Muluneh B, Li Q, et al. Revolutionizing patient-reported outcomes analysis for oncology drug development using population models. Clin Cancer Res, 2025, 31(9): 1580-1586.
- 100. Aanes SG, Wiig S, Nieder C, et al. Implementing digital patient-reported outcomes in routine cancer care: barriers and facilitators. ESMO Real World Data Digit Oncol, 2024, 6: 100088.
- 101. Cruz Rivera S, Liu X, Hughes SE, et al. Embedding patient-reported outcomes at the heart of artificial intelligence health-care technologies. Lancet Digit Health, 2023, 5(3): e168-e173.

