Transcatheter closure of atrial septal defect using fully biodegradable occluder under ultrasound guidance: A case report_Chinese Journal of Clinical Thoracic and Cardiovascular Surgery

Authors：

ZHAO Ying'ao ¹ , YAN Yiming ¹ , LI Ziping ¹ , LI Hang ¹ , ZHANG Fengwen ¹ , FANG Fang ¹ , ZHAO Guangzhi ¹ , DONG Jing ¹ , WANG Chuangshi ¹ , WANG Jiande ² ,  OUYANG Wenbin ¹ ,  PAN Xiangbin ¹

1. Department of Structural Heart Disease, National Center for Cardiovascular Diseases, Fuwai Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, National Health Commission Key Laboratory of Cardiovascular Regeneration Medicine, State Key Laboratory of Cardiovascular Disease, Key Laboratory of Innovative Cardiovascular Devices, Chinese Academy of Medical Sciences, National Clinical Research Center for Cardiovascular Diseases, Beijing, 100037, P. R. China;
2. Ultrasound Department, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, 100037, P. R. China;

Corresponding?author：

OUYANG Wenbin, Email: droywb31@163.com; PAN Xiangbin, Email: panxiangbin@fuwaihospital.org

Keywords：

Atrial septal defect; fully biodegradable occluder; echocardiography; transcatheter intervention

DOI：

10.7507/1007-4848.202312032

Video：

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Currently, transcatheter intervention is the preferred treatment for patients with anatomically suitable atrial septal defects. However, the use of nickel-titanium alloy occluders in interventional procedures results in lifelong presence of the implant in the body, leading to complications such as metal allergies and arrhythmias in some patients. To overcome the short-term and long-term complications associated with the presence of metal, and to avoid radiation exposure and metal toxicity, this paper reports a case of successful transcatheter closure of atrial septal defect in a pediatric patient with metal allergies using fully biodegradable occluder under ultrasound guidance, achieving excellent results by interventional therapy.

Citation： ZHAO Ying'ao, YAN Yiming, LI Ziping, LI Hang, ZHANG Fengwen, FANG Fang, ZHAO Guangzhi, DONG Jing, WANG Chuangshi, WANG Jiande, OUYANG Wenbin, PAN Xiangbin. Transcatheter closure of atrial septal defect using fully biodegradable occluder under ultrasound guidance: A case report. Chinese Journal of Clinical Thoracic and Cardiovascular Surgery, 2025, 32(12): 1796-1799. doi: 10.7507/1007-4848.202312032 Copy

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17.	Kong P, Liu X, Li Z, et al. Biodegradable cardiac occluder with surface modification by gelatin-peptide conjugate to promote endogenous tissue regeneration. Adv Sci (Weinh), 2023: e2305967.

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17. Kong P, Liu X, Li Z, et al. Biodegradable cardiac occluder with surface modification by gelatin-peptide conjugate to promote endogenous tissue regeneration. Adv Sci (Weinh), 2023: e2305967.

Chinese Journal of Clinical Thoracic and Cardiovascular Surgery

Transcatheter closure of atrial septal defect using fully biodegradable occluder under ultrasound guidance: A case report

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