宏基因組二代測序診斷貝納特柯克斯體致感染性心內膜炎三例_West China Medical Journal

Authors：

陸思芬 ¹ , 陳琪 ² , 胡珊 ³ , 江娟 ¹ , 張文庚 ¹ , 胡瓊霞 ¹ , 陶昕彤 ¹ , 張發強 ¹ ,  李鴻浩 ⁴ , 陳勃江 ¹

1. ;
2. ;
3. ;
4. ;

Corresponding?author：

李鴻浩, Email: lihonghao@wchscu.cn

Keywords：

感染性心內膜炎; 貝納特柯克斯體; 宏基因組二代測序; 多西環素

DOI：

10.7507/1002-0179.202507203

Video：

Export PDF Favorites Scan Get Citation

Abstract Full text Figures/Tables Video References Cited by

Citation： 陸思芬, 陳琪, 胡珊, 江娟, 張文庚, 胡瓊霞, 陶昕彤, 張發強, 李鴻浩, 陳勃江. 宏基因組二代測序診斷貝納特柯克斯體致感染性心內膜炎三例. West China Medical Journal, 2026, 41(4): 702-704. doi: 10.7507/1002-0179.202507203 Copy

1.	Li M, Kim JB, Sastry BKS, et al. Infective endocarditis. Lancet, 2024, 404(10450): 377-392.
2.	Latifian M, Mostafavi E, Broumand MA, et al. Molecular investigation of Coxiella burnetii and Bartonella in heart valve specimens of patients with endocarditis in Iran. J Infect Public Health, 2025, 18(1): 102616.
3.	郭昕卉, 陳亮, 郭強, 等. 感染性心內膜炎 239 例致病微生物分布及其優勢菌藥物敏感差異性. 藥品評價, 2023, 20(3): 318-321.
4.	Jaltotage B, Ali U, Dorai-Raj A, et al. Q fever endocarditis: a review of local and all reported cases in the literature. Heart Lung Circ, 2021, 30(10): 1509-1515.
5.	Zhan S, Jin H, Ji H, et al. Clinical diagnosis of Q fever by targeted next-generation sequencing for identification of Coxiella burnetii. BMC Infect Dis, 2025, 25(1): 190.
6.	Miller HK, Priestley RA, Kersh GJ. Q fever: a troubling disease and a challenging diagnosis. Clin Microbiol Newsl, 2021, 43(13): 109-118.
7.	Robinson MT, Satjanadumrong J, Hughes T, et al. Diagnosis of spotted fever group Rickettsia infections: the Asian perspective. Epidemiol Infect, 2019, 147: e286.
8.	Tolpinrud A, Stenos J, Chaber AL, et al. Validation of an indirect immunofluorescence assay and commercial Q fever enzyme-linked immunosorbent assay for use in macropods. J Clin Microbiol, 2022, 60(7): e0023622.
9.	Kim M, Fida M, Abu Saleh OM, et al. From culture-negative to DNA-positive: the molecular revolution in infective endocarditis diagnosis. Pathogens, 2025, 14(6): 518.
10.	宏基因組分析和診斷技術在急危重癥感染應用的專家共識組. 宏基因組分析和診斷技術在急危重癥感染應用的專家共識. 中華急診醫學雜志, 2019, 28(2): 151-155.
11.	Clay KA, Hartley MG, Whelan AO, et al. Evaluation of alternative doxycycline antibiotic regimes in an inhalational murine model of Q fever. Antibiotics (Basel), 2023, 12(5): 914.
12.	Paul M. Which trial do we need? Doxycycline vs. doxycycline-hydroxychloroquine and treatment duration protocol for Q fever endovascular infections. Clin Microbiol Infect, 2023, 29(12): 1468-1470.
13.	Nunes-Silva C, Rocha R, Martins A, et al. Guidelines for the treatment and follow-up of patients with Q fever. Acta Med Port, 2022, 35(6): 494-503.
14.	Eldin C, Mélenotte C, Mediannikov O, et al. From Q fever to Coxiella burnetii infection: a paradigm change. Clin Microbiol Rev, 2017, 30(1): 115-190.
15.	邢百倩, 劉虎南, 孫義紅, 等. 1 例肝硬化患者并發重癥鸚鵡熱的抗感染治療分析與監護. 藥物流行病學雜志, 2025, 34(11):1340-1346.

1. Li M, Kim JB, Sastry BKS, et al. Infective endocarditis. Lancet, 2024, 404(10450): 377-392.
2. Latifian M, Mostafavi E, Broumand MA, et al. Molecular investigation of Coxiella burnetii and Bartonella in heart valve specimens of patients with endocarditis in Iran. J Infect Public Health, 2025, 18(1): 102616.
3. 郭昕卉, 陳亮, 郭強, 等. 感染性心內膜炎 239 例致病微生物分布及其優勢菌藥物敏感差異性. 藥品評價, 2023, 20(3): 318-321.
4. Jaltotage B, Ali U, Dorai-Raj A, et al. Q fever endocarditis: a review of local and all reported cases in the literature. Heart Lung Circ, 2021, 30(10): 1509-1515.
5. Zhan S, Jin H, Ji H, et al. Clinical diagnosis of Q fever by targeted next-generation sequencing for identification of Coxiella burnetii. BMC Infect Dis, 2025, 25(1): 190.
6. Miller HK, Priestley RA, Kersh GJ. Q fever: a troubling disease and a challenging diagnosis. Clin Microbiol Newsl, 2021, 43(13): 109-118.
7. Robinson MT, Satjanadumrong J, Hughes T, et al. Diagnosis of spotted fever group Rickettsia infections: the Asian perspective. Epidemiol Infect, 2019, 147: e286.
8. Tolpinrud A, Stenos J, Chaber AL, et al. Validation of an indirect immunofluorescence assay and commercial Q fever enzyme-linked immunosorbent assay for use in macropods. J Clin Microbiol, 2022, 60(7): e0023622.
9. Kim M, Fida M, Abu Saleh OM, et al. From culture-negative to DNA-positive: the molecular revolution in infective endocarditis diagnosis. Pathogens, 2025, 14(6): 518.
10. 宏基因組分析和診斷技術在急危重癥感染應用的專家共識組. 宏基因組分析和診斷技術在急危重癥感染應用的專家共識. 中華急診醫學雜志, 2019, 28(2): 151-155.
11. Clay KA, Hartley MG, Whelan AO, et al. Evaluation of alternative doxycycline antibiotic regimes in an inhalational murine model of Q fever. Antibiotics (Basel), 2023, 12(5): 914.
12. Paul M. Which trial do we need? Doxycycline vs. doxycycline-hydroxychloroquine and treatment duration protocol for Q fever endovascular infections. Clin Microbiol Infect, 2023, 29(12): 1468-1470.
13. Nunes-Silva C, Rocha R, Martins A, et al. Guidelines for the treatment and follow-up of patients with Q fever. Acta Med Port, 2022, 35(6): 494-503.
14. Eldin C, Mélenotte C, Mediannikov O, et al. From Q fever to Coxiella burnetii infection: a paradigm change. Clin Microbiol Rev, 2017, 30(1): 115-190.
15. 邢百倩, 劉虎南, 孫義紅, 等. 1 例肝硬化患者并發重癥鸚鵡熱的抗感染治療分析與監護. 藥物流行病學雜志, 2025, 34(11):1340-1346.

Previous Article
Research progress and clinical application prospects of novel biomarkers for obstetric antiphospholipid syndrome

West China Medical Journal

宏基因組二代測序診斷貝納特柯克斯體致感染性心內膜炎三例

Abstract Full text Figures/Tables Video References Cited by

Previous Article

Format

Content