雙心室起搏室間間期優化新算法的研究_《華西醫學》

作者：

劉漢雄 , 鄧曉奇 , 蔡琳 , 李錦 , 童琳 ,  鄧玨琳

成都市第三人民醫院·重慶醫科大學附屬成都第二臨床學院心內科（成都，610031）;

關鍵詞：

雙心室起搏室間間期優化算法

DOI：

10.7507/1002-0179.20130435

視頻：

導出 下載 收藏 掃碼 引用

摘要 全文 圖表 視頻 參考文獻 施引文獻 補充材料

目的　提出雙心室起搏室間間期（VV）優化新算法，并驗證其合理性。方法　選擇2009年6月－2012年12月間在成都市第三人民醫院心內科住院的慢性心力衰竭并接受雙心室起搏是心臟再同步化治療的患者41例，根據心臟電－機械耦聯的原理，將體表心電圖和超聲指標的數量關系用新公式來表述，通過前瞻性自身對照研究來比較新算法與傳統方法的差異。結果　41例患者均分別采用新算法、傳統超聲法及腔內心電圖法進行VV優化，測主動脈血流速度時間積分（AVTI）并統計耗時。經方差分析顯示新算法的AVTI[（22.32 ± 3.48） cm]優于傳統腔內心電圖法的AVTI[（19.22 ± 3.07）cm]，組間差異有統計學意義（P＜0.05）；而新算法的耗時[（18.80 ± 3.30）min]較傳統超聲法的耗時[（203.81 ± 20.12）min]明顯減少，組間差異有統計學意義（P＜0.01）。結論　新算法用于雙心室起搏是心臟再同步化治療的VV優化準確、快速，具有合理性及臨床推廣價值。

引用本文： 劉漢雄,鄧曉奇,蔡琳,李錦,童琳,鄧玨琳. 雙心室起搏室間間期優化新算法的研究. 華西醫學, 2013, 28(9): 1380-1383. doi: 10.7507/1002-0179.20130435 復制

1.	Hua W, Wang DM, Cai L, et al. A prospective study to evaluate the efficacy of an intracardiac electrogram-based atrioventricular and interventricular intervals optimization method in cardiac resynchronization therapy[J]. Chin Med J, 2012, 125(3): 428-433.
2.	孫欣, 王浩, 江勇, 等. 應用超聲心動圖指導心臟再同步化治療的室間間期優化[J].中華醫學超聲雜志(電子版), 2012, 9(2): 23-26.
3.	Lecoq G, Leclercq C, Leray E, et al. Clinical and electrocardiographic predictors of a positive response to cardiac resynchronization therapy in advanced heart failure[J]. Eur Heart J, 2005, 26(11): 1094-1100.
4.	Ritter P, Padeletti L, Gillio-Meina L, et al. Determination of the optimal atrioventricular delay in DDD pacing. Comparison between echo and peak endocardial acceleration measurements[J]. Europace, 2001, 1(2): 126-130.
5.	Jansen AH, Bracke FA, van Dantzig JM, et al. Correlation of echo Doppler optimization of atrioventricular delay in cardiac resynchronization therapy with invasive hemodynamics in patients with heart failure secondary to ischemic or idiopathic dilated cardiomyopathy[J]. Am J Cardiol, 2006, 97(4): 552-557.
6.	Sogaard P, Egeblad H, Pedersen AK, et al. Sequential versus simultaneous biventricular resynchronization for severe heart failure: evaluation by tissue Doppler imaging[J]. Circulation, 2002, 106(16): 2078-2084.
7.	van Gelder BM, Meijer A, Bracke FA. The optimized V-V interval determined by interventricular conduction times versus invasive measurement by LVdP/dTMAX[J]. J Cardiovasc Electrophysiol, 2008,19(9): 939-944.
8.	楊立波, 賈紹斌, 張華. 一鍵優化心臟再同步化治療慢性心力衰竭的療效觀察[J]. 臨床心血管病雜志, 2011, 27(4): 271-274.
9.	Min X, Meine M, Baker JH, et al. Estimation of the optimal VV delay by an IEGM-based method in cardiac resynchronization therapy[J]. Pacing Clin Electrophysiol, 2007, 30(Suppl 1): S19-S22.
10.	Kerlan JE, Sawney NS, Waggoner AD, et al. Prospective comparison of optimization methods for cardiac resynchronization therapy[J]. Heart Rhythm, 2006, 3(2): 148-154.
11.	Kohl P, Bollensdorff C, Garny A. Effects of mechanosensitive ion channels on ventricular electrophysiology: experimental and theoretical models[J]. Exp Physiol, 2006, 91(2): 307-321.
12.	Baker JH, McKenzie J, Beau S, et al. Acute evaluation of programmer-guided AV/PV and VV delay optimization comparing an IEGM method and echocardiogram for cardiac resynchronization therapy in heart failure patients and dual-chamber ICD implants[J]. J Cardiovasc Electrophysiol, 2007, 18(2): 185-191.

1. 　Hua W, Wang DM, Cai L, et al. A prospective study to evaluate the efficacy of an intracardiac electrogram-based atrioventricular and interventricular intervals optimization method in cardiac resynchronization therapy[J]. Chin Med J, 2012, 125(3): 428-433.
2. 　孫欣, 王浩, 江勇, 等. 應用超聲心動圖指導心臟再同步化治療的室間間期優化[J].中華醫學超聲雜志(電子版), 2012, 9(2): 23-26.
3. 　Lecoq G, Leclercq C, Leray E, et al. Clinical and electrocardiographic predictors of a positive response to cardiac resynchronization therapy in advanced heart failure[J]. Eur Heart J, 2005, 26(11): 1094-1100.
4. 　Ritter P, Padeletti L, Gillio-Meina L, et al. Determination of the optimal atrioventricular delay in DDD pacing. Comparison between echo and peak endocardial acceleration measurements[J]. Europace, 2001, 1(2): 126-130.
5. 　Jansen AH, Bracke FA, van Dantzig JM, et al. Correlation of echo Doppler optimization of atrioventricular delay in cardiac resynchronization therapy with invasive hemodynamics in patients with heart failure secondary to ischemic or idiopathic dilated cardiomyopathy[J]. Am J Cardiol, 2006, 97(4): 552-557.
6. 　Sogaard P, Egeblad H, Pedersen AK, et al. Sequential versus simultaneous biventricular resynchronization for severe heart failure: evaluation by tissue Doppler imaging[J]. Circulation, 2002, 106(16): 2078-2084.
7. 　van Gelder BM, Meijer A, Bracke FA. The optimized V-V interval determined by interventricular conduction times versus invasive measurement by LVdP/dTMAX[J]. J Cardiovasc Electrophysiol, 2008,19(9): 939-944.
8. 　楊立波, 賈紹斌, 張華. 一鍵優化心臟再同步化治療慢性心力衰竭的療效觀察[J]. 臨床心血管病雜志, 2011, 27(4): 271-274.
9. 　Min X, Meine M, Baker JH, et al. Estimation of the optimal VV delay by an IEGM-based method in cardiac resynchronization therapy[J]. Pacing Clin Electrophysiol, 2007, 30(Suppl 1): S19-S22.
10. 　Kerlan JE, Sawney NS, Waggoner AD, et al. Prospective comparison of optimization methods for cardiac resynchronization therapy[J]. Heart Rhythm, 2006, 3(2): 148-154.
11. 　Kohl P, Bollensdorff C, Garny A. Effects of mechanosensitive ion channels on ventricular electrophysiology: experimental and theoretical models[J]. Exp Physiol, 2006, 91(2): 307-321.
12. 　Baker JH, McKenzie J, Beau S, et al. Acute evaluation of programmer-guided AV/PV and VV delay optimization comparing an IEGM method and echocardiogram for cardiac resynchronization therapy in heart failure patients and dual-chamber ICD implants[J]. J Cardiovasc Electrophysiol, 2007, 18(2): 185-191.

《華西醫學》

雙心室起搏室間間期優化新算法的研究

摘要 全文 圖表 視頻 參考文獻 施引文獻 補充材料

上一篇

下一篇

Format

Content

《華西醫學》

雙心室起搏室間間期優化新算法的研究

摘要 全文 圖表 視頻 參考文獻 施引文獻 補充材料

上一篇

下一篇

Format

Content

摘要全文圖表視頻參考文獻施引文獻補充材料