胎兒心臟房室傳導的研究進展_《華西醫學》

作者：

郭敏 ¹ ,  朱琦 ²

1 電子科技大學醫院婦產科（成都，611731）;2 四川大學華西第二醫院超聲科;

關鍵詞：

胎兒房室傳導時間縫隙連接超聲診斷房室傳導阻滯

DOI：

10.7507/1002-0179.20130412

視頻：

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房室傳導是胎兒心臟電生理活動的基礎；房室傳導阻滯的發生將嚴重影響心臟泵血功能，并危害胎兒健康。現著重對胎兒房室傳導的生理、病理及臨床等方面的研究進展進行介紹，旨在為胎兒房室傳導阻滯等心臟疾病的篩查提供參考。

引用本文： 郭敏,朱琦. 胎兒心臟房室傳導的研究進展. 華西醫學, 2013, 28(8): 1311-1314. doi: 10.7507/1002-0179.20130412 復制

1.	Ansalone G, Giannantoni P, Ricci R, et al. Doppler myocardial imaging in patients with heart failure receiving biventricular pacing treatment[J]. Am Heart J, 2001, 142(5): 881-896.
2.	Nii M, Hamilton RM, Fenwick L, et al. Assessment of fetal atrioventricular time intervals by tissue Doppler and pulse Doppler echocardiography: normal values and correlation with fetal electrocardiography[J]. Heart, 2006, 92(12): 1831-1837.
3.	Chia EL, Ho TF, Rauff M, et al. Cardiac time intervals of normal fetuses using noninvasive fetal electrocardiography[J]. Prenat Diagn, 2005, 25(7): 546-552.
4.	van Leeuwen P, Schiermeier S, Lange S, et al. Gender-related changes in magnetocardiographically determined fetal cardiac time intervals in intrauterine growth retardation[J]. Pediatr Res, 2006, 59(6): 820-824.
5.	Wheeler T, Murrills A. Patterns of fetal heart rate during normal pregnancy[J]. Br J Obstet Gynaecol, 1978, 85(1): 18–27.
6.	Firpo C, Hoffman JI, Silverman NH. Evaluation of fetal heart dimensions from 12 weeks to term[J]. Am J Cardiol, 2001, 87(5): 594-600.
7.	Schwartz PJ, Garson AJ, Paul T, et al. 新生兒心電圖判讀指南(一)[J]. 中華婦幼臨床醫學雜志, 2008, 4(6): 600-603.
8.	Sonesson SE, Salomonsson S, Jacobsson LA, et al. Signs of first-degree heart block occur in one-third of fetuses of pregnant women with anti-SSA/Ro 52-kd antibodies[J]. Arthritis Rheum, 2004, 50(4): 1253-1261.
9.	Nii M, Shimizu M, Roman KS, et al. Doppler tissue imaging in the assessment of atrioventricular conduction time: validation of a novel technique and comparison with electrophysiologic and pulsed wave doppler-derived equivalents in an animal model[J]. J Am Soc Echocardiogr, 2006, 19(3): 314-321.
10.	Rein AJ, O’donnell C, Geva T, et al. Use of tissue velocity imaging in the diagnosis of fetal cardiac arrhythmias[J]. Circulation, 2002, 106(14): 1827-1833.
11.	Vergani P, Mariani E, Ciriello E, et al. Fetal arrhythmias: natural history and management[J]. Ultrasound Med Biol, 2005, 31(1): 1-6.
12.	張玉娟, 吳瑛. 組織多普勒成像和心磁圖在胎兒心律失常研究中的應用[J]. 中國介入影像與治療學, 2008, 5(3): 243-245.
13.	Hosono T. Fetal magnetocardiography[J]. Rinsho Byori, 2006, 54(5): 477-485.
14.	Campbell JQ, Best TH, Eswaran H, et al. Fetal and maternal magnetocardiography during flecainide therapy for supraventricular tachycardia[J]. Obstet Gynecol, 2006, 108(3 Pt 2): 767-771.
15.	劉芳, 陳元祿. 心磁圖的臨床應用及相關比較研究[J]. 中國心血管雜志, 2005, 10(6): 472-475.
16.	楊慧, 朱琦. 胎兒心律失常的研究現狀[J]. 西部醫學, 2010, 22(11): 2154-2156.
17.	Rein AJ, Mevorach D, Perles Z, et al. Early diagnosis and treatment of atrioventricular block in the fetus exposed to maternal anti-SSA/Ro-SSB/La antibodies: a prospective, observational, fetal kinetocardiogram-based study[J]. Circulation, 2009, 119(14): 1867-1872.
18.	Buyon JP, Clancy RM, Friedman DM. Autoimmune associated congenital heart block: integration of clinical and research clues in the management of the maternal / foetal dyad at risk[J]. J Intern Med, 2009, 265(6): 653-662.
19.	Mevorach D, Elchalal U, Rein AJ. Prevention of complete heart block in children of mothers with anti-SSA/Ro and anti-SSB/La autoantibodies: detection and treatment of first-degree atrioventricular block[J]. Curr Opin Rheumatol, 2009, 21(5): 478-482.
20.	Vesel S, Zavrsnik T, Podnar T. Successful outcome in a fetus with an extremely low heart rate due to isolated complete congenital heart block[J]. Ultrasound Obstet Gynecol, 2003, 21(2): 189-191.
21.	樊慶泊, 邢菲菲, 蓋銘英, 等. 胎兒心律失常的診斷和治療進展[J]. 國外醫學·婦產科學分冊, 2005, 32(1): 1-3.
22.	Jaeggi ET, Nii M. Fetal brady- and tachyarrhythmias: new and accepted diagnostic and treatment methods[J]. Semin Fetal Neonatal Med, 2005, 10(6): 504-514.
23.	Jaeggi ET, Fouron JC, Silverman ED, et al. Transplacental fetal treatment improves the outcome of prenatally diagnosed complete atrioventricular block without structural heart disease[J]. Circulation, 2004, 110(12): 1542-1548.
24.	Duke C, Stuart G, Simpson JM. Ventricular tachycardia secondary to prolongation of the QT interval in a fetus with autoimmune mediated congenital complete heart block[J]. Cardiol Young, 2005, 15(3): 319-321.

1. 　Ansalone G, Giannantoni P, Ricci R, et al. Doppler myocardial imaging in patients with heart failure receiving biventricular pacing treatment[J]. Am Heart J, 2001, 142(5): 881-896.
2. 　Nii M, Hamilton RM, Fenwick L, et al. Assessment of fetal atrioventricular time intervals by tissue Doppler and pulse Doppler echocardiography: normal values and correlation with fetal electrocardiography[J]. Heart, 2006, 92(12): 1831-1837.
3. 　Chia EL, Ho TF, Rauff M, et al. Cardiac time intervals of normal fetuses using noninvasive fetal electrocardiography[J]. Prenat Diagn, 2005, 25(7): 546-552.
4. 　van Leeuwen P, Schiermeier S, Lange S, et al. Gender-related changes in magnetocardiographically determined fetal cardiac time intervals in intrauterine growth retardation[J]. Pediatr Res, 2006, 59(6): 820-824.
5. 　Wheeler T, Murrills A. Patterns of fetal heart rate during normal pregnancy[J]. Br J Obstet Gynaecol, 1978, 85(1): 18–27.
6. 　Firpo C, Hoffman JI, Silverman NH. Evaluation of fetal heart dimensions from 12 weeks to term[J]. Am J Cardiol, 2001, 87(5): 594-600.
7. 　Schwartz PJ, Garson AJ, Paul T, et al. 新生兒心電圖判讀指南(一)[J]. 中華婦幼臨床醫學雜志, 2008, 4(6): 600-603.
8. 　Sonesson SE, Salomonsson S, Jacobsson LA, et al. Signs of first-degree heart block occur in one-third of fetuses of pregnant women with anti-SSA/Ro 52-kd antibodies[J]. Arthritis Rheum, 2004, 50(4): 1253-1261.
9. 　Nii M, Shimizu M, Roman KS, et al. Doppler tissue imaging in the assessment of atrioventricular conduction time: validation of a novel technique and comparison with electrophysiologic and pulsed wave doppler-derived equivalents in an animal model[J]. J Am Soc Echocardiogr, 2006, 19(3): 314-321.
10. 　Rein AJ, O’donnell C, Geva T, et al. Use of tissue velocity imaging in the diagnosis of fetal cardiac arrhythmias[J]. Circulation, 2002, 106(14): 1827-1833.
11. 　Vergani P, Mariani E, Ciriello E, et al. Fetal arrhythmias: natural history and management[J]. Ultrasound Med Biol, 2005, 31(1): 1-6.
12. 　張玉娟, 吳瑛. 組織多普勒成像和心磁圖在胎兒心律失常研究中的應用[J]. 中國介入影像與治療學, 2008, 5(3): 243-245.
13. 　Hosono T. Fetal magnetocardiography[J]. Rinsho Byori, 2006, 54(5): 477-485.
14. 　Campbell JQ, Best TH, Eswaran H, et al. Fetal and maternal magnetocardiography during flecainide therapy for supraventricular tachycardia[J]. Obstet Gynecol, 2006, 108(3 Pt 2): 767-771.
15. 　劉芳, 陳元祿. 心磁圖的臨床應用及相關比較研究[J]. 中國心血管雜志, 2005, 10(6): 472-475.
16. 　楊慧, 朱琦. 胎兒心律失常的研究現狀[J]. 西部醫學, 2010, 22(11): 2154-2156.
17. 　Rein AJ, Mevorach D, Perles Z, et al. Early diagnosis and treatment of atrioventricular block in the fetus exposed to maternal anti-SSA/Ro-SSB/La antibodies: a prospective, observational, fetal kinetocardiogram-based study[J]. Circulation, 2009, 119(14): 1867-1872.
18. 　Buyon JP, Clancy RM, Friedman DM. Autoimmune associated congenital heart block: integration of clinical and research clues in the management of the maternal / foetal dyad at risk[J]. J Intern Med, 2009, 265(6): 653-662.
19. 　Mevorach D, Elchalal U, Rein AJ. Prevention of complete heart block in children of mothers with anti-SSA/Ro and anti-SSB/La autoantibodies: detection and treatment of first-degree atrioventricular block[J]. Curr Opin Rheumatol, 2009, 21(5): 478-482.
20. 　Vesel S, Zavrsnik T, Podnar T. Successful outcome in a fetus with an extremely low heart rate due to isolated complete congenital heart block[J]. Ultrasound Obstet Gynecol, 2003, 21(2): 189-191.
21. 　樊慶泊, 邢菲菲, 蓋銘英, 等. 胎兒心律失常的診斷和治療進展[J]. 國外醫學·婦產科學分冊, 2005, 32(1): 1-3.
22. 　Jaeggi ET, Nii M. Fetal brady- and tachyarrhythmias: new and accepted diagnostic and treatment methods[J]. Semin Fetal Neonatal Med, 2005, 10(6): 504-514.
23. 　Jaeggi ET, Fouron JC, Silverman ED, et al. Transplacental fetal treatment improves the outcome of prenatally diagnosed complete atrioventricular block without structural heart disease[J]. Circulation, 2004, 110(12): 1542-1548.
24. 　Duke C, Stuart G, Simpson JM. Ventricular tachycardia secondary to prolongation of the QT interval in a fetus with autoimmune mediated congenital complete heart block[J]. Cardiol Young, 2005, 15(3): 319-321.

《華西醫學》

胎兒心臟房室傳導的研究進展

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《華西醫學》

胎兒心臟房室傳導的研究進展

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